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Long-term outcome of the humoral and cellular immune response of an H5N1 adjuvanted influenza vaccine in elderly persons: 2-year follow-up of a randomised open-label study

Background Older individuals often have a reduced immune response to influenza vaccination, which might be improved by administering a higher vaccine dose. We compared the immune response to two single doses of the AS03A-adjuvanted H5N1 pandemic vaccine (3.75 μg hemagglutinin of A/Vietnam/1194/2004) with that of two double vaccine doses (7.5 μg hemagglutinin) in adults aged ≥61...

Long-term booster schedules with AS03A-adjuvanted heterologous H5N1 vaccines induces rapid and broad immune responses in Asian adults

Shinn-Jang Hwang 1 Pan-Chyr Yang 6 Prasert Thongcharoen 5 Fong Seng Lim 4 Mamadou Dramé 3 Karl Walravens 7 François Roman 7 0 GlaxoSmithKline Vaccines , Wavre , Belgium 1 Department of Family Medicine

A serological and bacteriological survey of brucellosis in wild boar (Sus scrofa) in Belgium

Background Brucellosis is frequently reported among wild boar populations in Europe. The aim of the study was to assess the epidemiological situation in Belgium, regarding the steady increase of wild boar populations over the last decades. Several serological tests were used and compared with culture and IS711 polymerase chain reaction (PCR), to determine the most suitable...

MLVA-16 typing of 295 marine mammal Brucella isolates from different animal and geographic origins identifies 7 major groups within Brucella ceti and Brucella pinnipedialis

Maquart1, Philippe Le Flche2,3, Geoffrey Foster4, Morten Tryland5, Franoise Ramisse 0 Berit Djnne 5 Sascha Al Dahouk 4 9 Isabelle Jacques 3 8 Heinrich Neubauer 2 4 Karl Walravens 10 Jacques Godfroid 6