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Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina

for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, D-50931, Cologne, GermanyMarcus Karlstetter, Katharina Dannhausen & Thomas LangmannBayer AG, Wuppertal ... in:Nature Research journals • PubMed • Google Scholar Search for Yuxi Feng in:Nature Research journals • PubMed • Google Scholar Search for Katharina Dannhausen in:Nature Research journals • PubMed

Mikroglia und Immuntherapien bei degenerativen Netzhauterkrankungen

Netzhauterkrankungen 0 Lehrstuhl für Experimentelle Immunologie des Auges, Zentrum für Augenheilkunde , Uniklinik Köln, Köln , Deutschland Marcus Karlstetter · Katharina Dannhausen · Thomas Langmann Hintergrund

Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator

Background Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. The polymorphism rs10490924 in the ARMS2 gene is highly associated with AMD and linked to an indel mutation (del443ins54), the latter inducing mRNA instability. At present, the function of the ARMS2 protein, the exact cellular sources in the retina and the biological...