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The combination of cardiorespiratory fitness and muscle strength, and mortality risk

Little is known about the combined associations of cardiorespiratory fitness (CRF) and hand grip strength (GS) with mortality in general adult populations. The purpose of this study was to compare the relative risk of mortality for CRF, GS, and their combination. In UK Biobank, a prospective cohort of > 0.5 million adults aged 40–69 years, CRF was measured through submaximal bike...

Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis

Purpose: To estimate the strength and shape of the dose–response relationship between sedentary behaviour and all-cause, cardiovascular disease (CVD) and cancer mortality, and incident type 2 diabetes (T2D), adjusted for physical activity (PA). Data Sources: Pubmed, Web of Knowledge, Medline, Embase, Cochrane Library and Google Scholar (through September-2016); reference lists...

Cross-Sectional Associations of Objectively-Measured Physical Activity and Sedentary Time with Body Composition and Cardiorespiratory Fitness in Mid-Childhood: The PANIC Study

with Ethical Standards Paul Collings, Kate Westgate, Juuso Va¨isto¨, Katrien Wijndaele, Andrew Atkin, Eero Haapala, Niina Lintu, Tomi Laitinen, Ulf Ekelund, Soren Brage, and Timo Lakka declare that they

Sedentary Time and Physical Activity Surveillance Through Accelerometer Pooling in Four European Countries

, Katrien Wijndaele, Søren Brage, Jeroen Lakerveld , Johannes Brug and Hidde P. van der Ploeg declare that they have no conflicts of interest Objective The objective of this study was to pool, harmonise and

Combined influence of epoch length, cut-point and bout duration on accelerometry-derived physical activity

Background It is difficult to compare accelerometer-derived estimates of moderate-to-vigorous physical activity (MVPA) between studies due to differences in data processing procedures. We aimed to evaluate the effects of accelerometer processing options on total and bout-accumulated time spent in MVPA in adults. Methods 267 participants from the ProActive Trial provided 1236 days...

Magnitude and determinants of change in objectively-measured physical activity, sedentary time and sleep duration from ages 15 to 17.5y in UK adolescents: the ROOTS study

Background Self-reported physical activity (PA) and sleep duration (SLP) change markedly throughout adolescence. We sought to quantify changes in objectively-measured PA, sedentary time (ST) and SLP through adolescence, and to investigate baseline body composition and baseline activity levels as determinants of change. Methods Individually calibrated combined heart rate and...

Sedentary Behavior and Incident Cancer: A Meta-Analysis of Prospective Studies

Background Sedentary behavior is ubiquitous in modern adults' daily lives and it has been suggested to be associated with incident cancer. However, the results have been inconsistent. In this study, we performed a systematic review and meta-analysis of prospective cohort studies to clarify the association between sedentary behavior and incident cancer. Method PubMed and Embase...

Levels and patterns of objectively-measured physical activity volume and intensity distribution in UK adolescents: the ROOTS study

Background Few studies have quantified levels of habitual physical activity across the entire intensity range. We aimed to describe variability in total and intensity-specific physical activity levels in UK adolescents across gender, socio-demographic, temporal and body composition strata. Methods Physical activity energy expenditure and minutes per day (min/d) spent sedentary...

Increasing objectively measured sedentary time increases clustered cardiometabolic risk: a 6 year analysis of the ProActive study

Aims/hypothesis We aimed to quantify the associations between change in objectively measured sedentary and moderate-to-vigorous physical activity (MVPA) times and self-reported television viewing over 6 years and change in a clustered cardiometabolic risk score (CCMR), including and excluding waist circumference (CCMR without adiposity component, CCMR no adip ), and its...

Determinants of Change in Children’s Sedentary Time

Collaboration, is gratefully acknowledged. The work of Katrien Wijndaele is supported by a British Heart Foundation Intermediate Basic Science Research Fellowship (FS/12/58/29709). The SPEEDY study was funded by

Socio-demographic, psychosocial and home-environmental attributes associated with adults' domestic screen time

Background Sedentary behaviors (involving prolonged sitting time) are associated with deleterious health consequences, independent of (lack of) physical activity. To inform interventions, correlates of prevalent sedentary behaviors need to be identified. We examined associations of socio-demographic, home-environmental and psychosocial factors with adults' TV viewing time and...

Breastfeeding and Infant Temperament at Age Three Months

Background & Methods To examine the relationship between breastfeeding and maternally-rated infant temperament at age 3 months, 316 infants in the prospective Cambridge Baby Growth Study, UK had infant temperament assessed at age 3 months by mothers using the Revised Infant Behavior Questionnaire, which produces scores for three main dimensions of temperament derived from 14...

Objectively Measured Sedentary Time May Predict Insulin Resistance Independent of Moderate- and Vigorous-Intensity Physical Activity

Hendrik J.F. Helmerhorst Katrien Wijndaele Sren Brage Nicholas J. Wareham Ulf Ekelund OBJECTIVE-To examine the prospective association between objectively measured time spent sedentary and insulin

Television Viewing and Incident Cardiovascular Disease: Prospective Associations and Mediation Analysis in the EPIC Norfolk Study

Background Although television viewing time is detrimentally associated with intermediate cardiovascular risk factors, the relationship with incident total (i.e. combined fatal and non-fatal) cardiovascular disease (CVD), non-fatal CVD and coronary heart disease is largely unknown. This study examined whether television viewing time is associated with these three outcomes...

Dietary factors associated with obesity indicators and level of sports participation in Flemish adults: a cross-sectional study

Background Obesity develops when energy intake continuously exceeds energy expenditure, causing a fundamental chronic energy imbalance. Societal and behavioural changes over the last decades are held responsible for the considerable increase in sedentary lifestyles and inappropriate dietary patterns. The role of dietary fat and other dietary factors in the aetiology and...

Socio-economic and lifestyle factors associated with overweight in Flemish adult men and women

Background Changes in lifestyles and in the environment over the last decades are probably the most important cause of the overweight epidemic, but the findings are inconsistent among studies. The purpose of this study was to investigate the association of several socio-economic and lifestyle factors with overweight in Flemish adults, using BMI ≥ 25 kg/m2, waist circumference (WC...

Objectively Measured Sedentary Time, Physical Activity, and Metabolic Risk: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab)

OBJECTIVE—We examined the associations of objectively measured sedentary time and physical activity with continuous indexes of metabolic risk in Australian adults without known diabetes. RESEARCH DESIGN AND METHODS—An accelerometer was used to derive the percentage of monitoring time spent sedentary and in light-intensity and moderate-to-vigorous–intensity activity, as well as...

A Continuous Metabolic Syndrome Risk Score: Utility for epidemiological analyses

alternative for epidemiological analyses, although the binary definition (1) remains useful for clinical practice. KATRIEN WIJNDAELE, MA1 GASTON BEUNEN, PHD2 NATHALIE DUVIGNEAUD, MA3 LYNN MATTON, MA2 WILLIAM