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Usefulness of axonal tract-dependent OCT macular sectors for evaluating structural change in normal-tension glaucoma

assistance. Author Contributions Conceptualization: Toru Nakazawa. Data curation: Kazuko Omodaka, Yukihiro Shiga, Satoru Tsuda, Yu Yokoyama, Haruka Sato, Junko Ohuchi, Hidetoshi Takahashi. Funding ... acquisition: Toru Nakazawa. Investigation: Yukihiro Shiga, Satoru Tsuda. Methodology: Tsutomu Kikawa, Akiko Matsumoto, Masahiro Akiba. Project administration: Toru Nakazawa. Writing ± original draft: Kazuko

Differentiation of glaucomatous optic discs with different appearances using optic disc topography parameters: The Glaucoma Stereo Analysis Study

its Supporting Information file. Funding: Drs. Maki Katai, Yasushi Kitaoka, Yu Yokoyama, Kazuko, Omodaka, and Toru Nakazawa were provided a stereo fundus camera from Kowa Company, Ltd. for conducting

OCT-Based Quantification and Classification of Optic Disc Structure in Glaucoma Patients

Purpose To objectively classify the optic discs of open-angle glaucoma (OAG) patients into Nicolela's four disc types, i.e., focal ischemic (FI), myopic (MY), senile sclerotic (SS), and generalized enlargement (GE), with swept-source optical coherence tomography (SS-OCT). Methods This study enrolled 113 eyes of 113 OAG patients (mean age: 62.5 ± 12.6; Humphrey field ...

Age- and Sex-Dependency of Laser Speckle Flowgraphy Measurements of Optic Nerve Vessel Microcirculation

Purpose To investigate the relationship between various characteristics of a normal population and laser speckle flowgraphy (LSFG) measurements of mean blur rate (MBR) in the optic nerve head (ONH). Methods A total of 189 eyes of 189 normal subjects (93 male, 96 female, mean age 45 ± 14 years old, age range: 20–72) without any history of hypertension, hyperlipidemia or diabetes ...

Estimation of the Disc Damage Likelihood Scale in primary open-angle glaucoma: the Glaucoma Stereo Analysis Study

Purpose The Glaucoma Stereo Analysis Study (GSAS), a cross-sectional multicenter collaborative study, used a stereo fundus camera (nonmyd WX) to assess various morphological parameters of the optic nerve head (ONH) in glaucoma patients. We examined the associations between the Disc Damage Likelihood Scale (DDLS), a grading system for estimating glaucomatous ONH damage, and each ...

Retinal Thickness and the Structure/Function Relationship in the Eyes of Older Adults with Glaucoma

Glaucoma is common and shows high prevalence in older adults. However, there are few studies on the structure/function relationship in older adults with glaucoma. This prospective, cross-sectional study (conducted between February and August 2014), enrolled 102 eyes of 102 subjects aged over 75 years, including 57 eyes with primary open angle glaucoma (POAG), 15 eyes with ...

Clinical Factors Associated with Lamina Cribrosa Thickness in Patients with Glaucoma, as Measured with Swept Source Optical Coherence Tomography

Purpose To investigate the influence of various risk factors on thinning of the lamina cribrosa (LC), as measured with swept-source optical coherence tomography (SS-OCT; Topcon). Methods This retrospective study comprised 150 eyes of 150 patients: 22 normal subjects, 28 preperimetric glaucoma (PPG) patients, and 100 open-angle glaucoma patients. Average LC thickness was determined ...

3D Evaluation of the Lamina Cribrosa with Swept-Source Optical Coherence Tomography in Normal Tension Glaucoma

conflicts: The authors disclose a financial relationship with Topcon Corporation because of the patent pending related to this article applied by Kazuko Omodaka, Tsutomu Kikawa, Akiko Matsumoto, Masahiro

Correlation between structure/function and optic disc microcirculation in myopic glaucoma, measured with laser speckle flowgraphy

Background It is difficult to identify glaucoma in myopic eyes because the configuration of the optic disc varies; yet it is important clinically. Here, we used laser speckle flowgraphy (LSFG) to measure mean blur rate (MBR), representing optic disc microcirculation, and assessed its ability to identify glaucoma in eyes with myopic optic discs. Methods 129 eyes (normal disc: 21 ...

Stereoscopic Analysis of Optic Nerve Head Parameters in Primary Open Angle Glaucoma: The Glaucoma Stereo Analysis Study

Purpose The Glaucoma Stereo Analysis Study (GSAS), a cross sectional multicenter collaborative study, used a stereo fundus camera to assess various morphological parameters of the optic nerve head (ONH) in glaucoma patients and investigated the relationships between these parameters and patient characteristics. Subjects and Methods The study included 187 eyes of 187 subjects with ...