The functional connectivity of the default mode network (DMN) decreases in patients with Alzheimer’s disease (AD) as well as in patients with type 2 diabetes mellitus (T2DM). Altered functional connectivity of the DMN is associated with cognitive impairment. T2DM is a known cause of cognitive dysfunction and dementia in the elderly, and studies have established that T2DM is a...
Physical activity may preserve neuronal plasticity, increase synapse formation, and cause the release of hormonal factors that promote neurogenesis and neuronal function. Previous studies have reported enhanced neurocognitive function following exercise training. However, the specific cortical regions activated during exercise training remain largely undefined. In this study, we...
Background Many in vivo studies have shown a difference in pre- and/or postsynaptic imaging between Parkinson’s disease and multiple system atrophy; however, time course differences in pre- and postsynaptic imaging between Parkinson’s disease and multiple system atrophy have not been rigorously investigated. Case presentation We report serial positron emission tomography images...
Many in vivo studies have shown a difference in pre- and/or postsynaptic imaging between Parkinson’s disease and multiple system atrophy; however, time course differences in pre- and postsynaptic imaging between Parkinson’s disease and multiple system atrophy have not been rigorously investigated. We report serial positron emission tomography images of both dopamine transporters...
. Author information AffiliationsCardiovascular Research Institute, University of California, San Francisco, California, USAMark Kahn, Kenji Ishii, Andrew Connolly, Richard Wu & Shaun R. CoughlinDepartment ... , 505 Parnassus Avenue, HSW-831, San Francisco, CA, 94143-0524, USAShaun R. Coughlin AuthorsSearch for Mark Kahn in:PubMed • Google Scholar Search for Kenji Ishii in:PubMed • Google Scholar Search for