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Search: authors:"Kerstin Hellwig"

5 papers found.
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Oral Contraceptives and Multiple Sclerosis/Clinically Isolated Syndrome Susceptibility

Background The incidence of multiple sclerosis (MS) is rising in women. Objective To determine whether the use of combined oral contraceptives (COCs) are associated with MS risk and whether this varies by progestin content. Methods We conducted a nested case-control study of females ages 14–48 years with incident MS or clinically isolated syndrome (CIS) 2008–2011 from the...

Combinations of Susceptibility Genes Are Associated with Higher Risk for Multiple Sclerosis and Imply Disease Course Specificity

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that predominantly affects young adults. The genetic contributions to this multifactorial disease were underscored by a genome wide association study (GWAS) conducted by the International Multiple Sclerosis Genetic Consortium in a multinational cohort prompting the discovery of 57 non-MHC MS...

Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy

Caspar F Pfueller 0 Friedemann Paul 0 Jan Drr 0 Kerstin Hellwig 0 NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis , Charite - Universitatsmedizin

Efficacy of repeated intrathecal triamcinolone acetonide application in progressive multiple sclerosis patients with spinal symptoms

Background There are controversial results on the efficacy of the abandoned, intrathecal predominant methylprednisolone application in multiple sclerosis (MS) in contrast to the proven effectiveness in intractable postherpetic neuralgia. Methods We performed an analysis of the efficacy of the application of 40 mg of the sustained release steroid triamcinolone acetonide (TCA). We...

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

Tania Kuempfel Marius Ringelstein Christian Geis Ingo Kleiter Christoph Kleinschnitz Achim Berthele Johannes Brettschneider Kerstin Hellwig Bernhard Hemmer Ralf A Linker Florian Lauda Christoph A Mayer