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Search: authors:"Ko-Hsun Liao"

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Bone marrow concentrate-induced mesenchymal stem cell conditioned medium facilitates wound healing and prevents hypertrophic scar formation in a rabbit ear model

University, Taipei, TaiwanChing-Hsuan Hu, Yi-Wen Tseng, Chih-Yung Chiou, Ko-Hsun Liao & Oscar K. LeeStem Cell Research Center, National Yang-Ming University, Taipei, TaiwanChing-Hsuan Hu, Yi-Wen Tseng & Oscar ... Scholar Search for Hsien-Da Huang in:PubMed • Google Scholar Search for Chiung-Wen Hu in:PubMed • Google Scholar Search for Ko-Hsun Liao in:PubMed • Google Scholar Search for Shiow-Shuh Chuang in:PubMed

Delayed epidural transplantation of human induced pluripotent stem cell-derived neural progenitors enhances functional recovery after stroke

Induced pluripotent stem cell-derived neural progenitor cells (iPSC-NPCs) are a promising source of tailor-made cell therapy for neurological diseases. However, major obstacles to clinical use still exist. To circumvent complications related to intracerebral administration, we implanted human iPSC-NPCs epidurally over the peri-infarct cortex 7 days after permanent middle cerebral...

Endothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-β2 expression

Conceptualization: Muh-Hwa Yang, Shung-Haur Yang, Chi-Hung Lin, Wei-Lun Hwang, Oscar K. Lee. Data curation: Ko-Hsun Liao, Shing-Jyh Chang, Hsin-Chuan Chang, Tse-Shun Huang, Te Chia Feng, Wen-Wei Lin, Chuan-Chi ... Shih, Wei-Lun Hwang. Formal analysis: Ko-Hsun Liao, Wei-Lun Hwang. Funding acquisition: Chuan-Chi Shih, Muh-Hwa Yang, Shung-Haur Yang, Wei-Lun Hwang, Oscar K. Lee. Investigation: Ko-Hsun Liao, Shing

MicroRNA-134 Contributes to Glucose-Induced Endothelial Cell Dysfunction and This Effect Can Be Reversed by Far-Infrared Irradiation

Diabetes mellitus (DM) is a metabolic disease that is increasing worldwide. Furthermore, it is associated with the deregulation of vascular-related functions, which can develop into major complications among DM patients. Endothelial colony forming cells (ECFCs) have the potential to bring about medical repairs because of their post-natal angiogenic activities; however, such...

Mesenchymal Stem Cells from Human Umbilical Cord Express Preferentially Secreted Factors Related to Neuroprotection, Neurogenesis, and Angiogenesis

Mesenchymal stem cells (MSCs) are promising tools for the treatment of diseases such as infarcted myocardia and strokes because of their ability to promote endogenous angiogenesis and neurogenesis via a variety of secreted factors. MSCs found in the Wharton’s jelly of the human umbilical cord are easily obtained and are capable of transplantation without rejection. We isolated...

Dysregulated miR-361-5p/VEGF Axis in the Plasma and Endothelial Progenitor Cells of Patients with Coronary Artery Disease

Dysfunction and reduction of circulating endothelial progenitor cell (EPC) is correlated with the onset of cardiovascular disorders including coronary artery disease (CAD). VEGF is a known mitogen for EPC to migrate out of bone marrow to possess angiogenic activities, and the plasma levels of VEGF are inversely correlated to the progression of CAD. Circulating microRNAs (miRNAs...