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A Population-Based Study of Hepatitis D Virus as Potential Risk Factor for Hepatocellular Carcinoma

Jianguang Ji Jianguang.ji@med 0 Kristina Sundquist 0 Jan Sundquist 0 0 Floor 11, Entrance 72, Skne University Hospital , Malm 205 02, Sweden ( Hepatitis D virus (HDV) is dependent on the presence of

A culturally adapted lifestyle intervention addressing a Middle Eastern immigrant population at risk of diabetes, the MEDIM (impact of Migration and Ethnicity on Diabetes In Malmö): study protocol for a randomized controlled trial

Background Studies have shown that lifestyle interventions are effective in preventing or delaying the onset of type 2 diabetes in high-risk patients. However, research on the effectiveness of lifestyle interventions in high-risk immigrant populations with different cultural and socioeconomic backgrounds is scarce. The aim was to design a culturally adapted lifestyle intervention ...

A healthy diet with and without cereal grains and dairy products in patients with type 2 diabetes: study protocol for a random-order cross-over pilot study - Alimentation and Diabetes in Lanzarote -ADILAN

Background Research on the role of nutrition in type 2 diabetes has largely focused on macro/micronutrient composition and dietary fiber intake, while fewer studies have tested the effects of differing food choice. Some observational studies and short-term intervention studies suggest that a food pattern mimicking the diet with which humans evolved positively influences glucose ...

Association between TLR9 rs5743836 polymorphism and risk of recurrent venous thromboembolism

biobank services at Biobank, Lab medicine Skåne, Sweden. We also thank science editor Patrick Reilly for language editing of this manuscript. grants awarded to Dr Bengt Zöller and Dr Kristina Sundquist by ... and Dr Kristina Sundquist, Informed consent This research involving human participants and an informed consent was obtained from all individual participants included in the study. Open Access This

Association between antithrombotic treatment and hemorrhagic stroke in patients with atrial fibrillation—a cohort study in primary care

balanced. Acknowledgments This work was supported by grants to Kristina Sundquist and Jan Sundquist from the Swedish Research Council (K2012-70X-15428-08-3) as well as ALF funding (88009) to Jan Sundquist ... and Kristina Sundquist from the Region Skåne. Research reported in this publication was also supported by the National Heart, Lung, and Blood Institute of the National Institutes of Health under Award

Autism and attention-deficit/hyperactivity disorder among individuals with a family history of alcohol use disorders

Recent studies suggest de novo mutations may involve the pathogenesis of autism and attention-deficit/hyperactivity disorder (ADHD). Based on the evidence that excessive alcohol consumption may be associated with an increased rate of de novo mutations in germ cells (sperms or eggs), we examine here whether the risks of autism and ADHD are increased among individuals with a family ...

Availability of exercise facilities and physical activity in 2,037 adults: cross-sectional results from the Swedish neighborhood and physical activity (SNAP) study

Ulf Eriksson 0 Daniel Arvidsson 0 Kristina Sundquist 0 0 Center for Primary Health Care Research, Lund University, Skane University Hospital , CRC, Building 28, Floor 11, Entrance 72, S-205 02 ... grants to Dr Kristina Sundquist from the Swedish Council for Working Life and Social Research (FAS; 2006-0386) and The Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning

Causes of death in patients with extranodal cancer of unknown primary: searching for the primary site

Background Cancer of unknown primary (CUP) is a fatal cancer, accounting for 3–5% of all diagnosed cancers. Finding the primary site is important for therapeutic choices and we believe that the organ which is designated as the cause of death may give clues about the primary site. Methods A total of 20,570 patients with CUP were identified from the Swedish Family-Cancer Database. ...

Circulating microRNA-144-5p is associated with depressive disorders

Background Depressive/anxiety disorders are the most common types of mental illnesses in the world. The present study was the first to explore the association between plasma microRNAs (miRNAs) and depression/anxiety in primary care patients. Results In total, 169 patients (aged 20–64 years) from 16 primary health centers were enrolled in the present study. The healthy controls were ...

Co-Morbidity between Early-Onset Leukemia and Type 1 Diabetes – Suggestive of a Shared Viral Etiology?

Background Acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are common early-onset malignancies. Their causes are largely unknown but infectious etiology has been implicated. Type 1 diabetes (T1D) is an autoimmune disease for which infectious triggers of disease onset have been sought and increasing pointing to enteroviruses. Based on our previous results on ...

Comparison of survival of patients with metastases from known versus unknown primaries: survival in metastatic cancer

Background Cancer of unknown primary site (CUP) is considered an aggressive metastatic disease but whether the prognosis differs from metastatic cancers of known primary site is not known. Such data may give insight into the biology of CUP and the metastatic process in general. Methods 6,745 cancer patients, with primary metastatic cancer at diagnosis, were identified from the ...

Determination of 14 Circulating microRNAs in Swedes and Iraqis with and without Diabetes Mellitus Type 2

Background Recent reports suggest that immigrants from Middle Eastern countries are a high-risk group for type 2 diabetes (T2D) compared with Swedes, and that the pathogenesis of T2D may be ethnicity-specific. Deregulation of microRNA (miRNA) expression has been demonstrated to be associated with T2D but ethnic differences in miRNA have not been investigated. The aim of this study ...

Dietary differences between elderly Iranians living in Sweden and Iran a cross-sectional comparative study

Background During the last decades, global migration has increased and many immigrant groups have a higher prevalence than the native born population of several cardiovascular disease risk factors, including poor dietary habits. However, it is uncertain if dietary habits in immigrant populations reflect dietary habits in their country of origin or if the current diet is a ...

Digested wheat gluten inhibits binding between leptin and its receptor

Background Leptin resistance is considered a primary risk factor for obesity. It has been hypothesized that dietary cereal grain protein could cause leptin resistance by preventing leptin from binding to its receptor. Non-degraded dietary wheat protein has been found in human serum at a mean level of 41 ng/mL. Here, we report our findings from testing whether enzymatically digested ...

Do Reproductive Factors Influence T, N, and M Classes of Ductal and Lobular Breast Cancers? A Nation-Wide Follow-Up Study

Backgrounds The clinical tumor-node-metastasis (T, N and M) classes of breast cancers provide important prognostic information. However, the possible association of TNM classes with reproductive factors has remained largely unexplored. Because every woman has a reproductive history, implications to outcome prediction are potentially significant. Methods During the study period from ...

Does the risk of stomach cancer remain among second-generation immigrants in Sweden?

The observed increased risks of noncardia stomach cancer among foreign-born second-generation immigrants compared to the Swedes suggest that these immigrants were infected by Helicobacter pylori before immigration.

Effect of a primary health-care-based controlled trial for cardiorespiratory fitness in refugee women

Sundquist 0 2 0 Center for Primary Health Care Research, CRC, Lund University , Malmö , Sweden 1 Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet

Effect of autoimmune diseases on incidence and survival in subsequent multiple myeloma

Background Patients with many types of autoimmune diseases (AIDs) are at an increased risk of cancer, which may depend on underlying dysregulation of the immune system or treatment. We systematically analyzed myeloma risk and survival in patients diagnosed with 33 different AIDs. Methods Data on patients with AIDs were retrieved from the Swedish Hospital Discharge Register and were ...

Effects of prescribed antithrombotics and other cardiovascular pharmacotherapies on all-cause mortality in patients with diabetes and atrial fibrillation – a cohort study from Sweden using propensity score analyses

Laplace regression method. All authors read and approved the final manuscript. Acknowledgments This work was supported by grants to Dr Kristina Sundquist from the Swedish Research Council (K2009-70X-15428 ... -05-3; K2012-70X-15428-08-3), to Dr Jan Sundquist from the Swedish Freemasons Foundation as well as ALF funding from Region Skåne awarded to Jan Sundquist and Kristina Sundquist. 1. Wirehn AB

Familial Risks for Type 2 Diabetes in Sweden

KARI HEMMINKI PHD XINJUN LI PHD KRISTINA SUNDQUIST PHD JAN SUNDQUIST PHD E p i d e m i o l o g y / H e a l t h OBJECTIVE - Our aim was to characterize familial risks for type 2 diabetes by the type