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Association of time-serial changes in ambient particulate matters (PMs) with respiratory emergency cases in Taipei's Wenshan District

-Wang Hsu. Software: Shih-Chang Hsu. Supervision: Shau-Ku Huang, Chin-Wang Hsu. Validation: Jer-Hwa Chang, Shih-Chang Hsu, Kuan-Jen Bai, Shau-Ku Huang. Visualization: Shih-Chang Hsu, Kuan-Jen Bai ... . Writing ± original draft: Jer-Hwa Chang. Writing ± review & editing: Jer-Hwa Chang, Shih-Chang Hsu, Kuan-Jen Bai, Shau-Ku Huang, Chin-Wang Hsu. 10 / 12 14. World Health Organization. Review of evidence

PPARs modulate cardiac metabolism and mitochondrial function in diabetes

Diabetic cardiomyopathy is a major complication of diabetes mellitus (DM). Currently, effective treatments for diabetic cardiomyopathy are limited. The pathophysiology of diabetic cardiomyopathy is complex, whereas mitochondrial dysfunction plays a vital role in the genesis of diabetic cardiomyopathy. Metabolic regulation targeting mitochondrial dysfunction is expected to be a...

The Influence of Smoking on Pulmonary Tuberculosis in Diabetic and Non-Diabetic Patients

Background Both smoking and diabetes can increase the risk and influence the manifestations and outcomes of tuberculosis (TB). It is not clear whether the influence of smoking on pulmonary TB differs between non-diabetic and diabetic patients. Herein, we assessed the manifestations and outcomes of TB in relation to smoking in both diabetic and non-diabetic TB patients...

Activation of p53/miR-34a Tumor Suppressor Axis by Chinese Herbal Formula JP-1 in A549 Lung Adenocarcinoma Cells

-Shrian Huang,2 Kuan-Jen Bai,5,6 and Gi-Ming Lai1,2,3,4 1Cancer Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan 2Comprehensive Cancer Center of Taipei Medical University, Taipei ... interests. Authors’ Contributions Gi-Ming Lai and Kuan-Jen Bai equally contributed to the paper. Acknowledgments The authors would like to thank Peter Sheng M.D. Inc. for providing the JP-1 powder. This work

Surveillance of Tuberculosis in Taipei: The Influence of Nontuberculous Mycobacteria

Background Notification of tuberculosis (TB) but not nontuberculous mycobacteria (NTM) is mandatory in Taiwan. Partly due to the strict regulation on TB notification, several patients infected with NTM were notified as TB cases. Notification of patients infected with NTM as TB cases can trigger public health actions and impose additional burdens on the public health system. We...

The Influence of Diabetes, Glycemic Control, and Diabetes-Related Comorbidities on Pulmonary Tuberculosis

Background To assess the influence of diabetes mellitus (DM), glycemic control, and diabetes-related comorbidities on manifestations and outcome of treatment of pulmonary tuberculosis (TB). Methodology/Principal Findings Culture positive pulmonary TB patients notified to health authorities in three hospitals in Taiwan from 2005–2010 were investigated. Glycemic control was...

Glycemic Control and Radiographic Manifestations of Tuberculosis in Diabetic Patients

Background Radiographic manifestations of pulmonary tuberculosis (TB) in patients with diabetes mellitus (DM) have previously been reported, with inconsistent results. We conducted a study to investigate whether glycemic control has an impact on radiographic manifestations of pulmonary TB. Methods Consecutive patients with culture-positive pulmonary TB who had DM in three...

Improved Consistency in Dosing Anti-Tuberculosis Drugs in Taipei, Taiwan

Background It was reported that 35.5% of tuberculosis (TB) cases reported in 2003 in Taipei City had no recorded pre-treatment body weight and that among those who had, inconsistent dosing of anti-TB drugs was frequent. Taiwan Centers for Disease Control (CDC) have taken actions to strengthen dosing of anti-TB drugs among general practitioners. Prescribing practices of anti-TB...