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72 papers found.
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Genesis of Miocene litho-stratigraphic trap and hydrocarbon accumulation in the Qiongdongnan Basin, northern South China Sea

In recent years, several large gas fields have been discovered in western Qiongdongnan Basin. It is important and necessary to illustrate their sedimentary characteristics and hydrocarbon migration so that more gas fields could be discovered in the future. Previous regional tectonic-sedimentary researchers show that large-scale source rock of the Yacheng Formation developed in...

Antimicrobial activity of puffball(Bovistella radicata) and separation of bioactive compounds

Background To test the antimicrobial activity of different extracts and fermentation broth from puffball(Bovistella radicata), the different extracts and fermentation broth of puffball were prepared, the active fraction was investigated by UPLC–UV–MS and semi-preparative chromatograph. Results Through zones of inhibition (ZOI) and minimum inhibitory concentrations (MIC) tests...

Testing and comparing two self-care-related instruments among older Chinese adults

, Xianfei Ding, Yanjin Liu. Formal analysis: Lina Guo, Xianfei Ding, Yanjin Liu. Investigation: Lina Guo, Han Gao, Qiyun Guo. Methodology: Lina Guo. Project administration: Lina Guo, Kun Liu, Yanjin Liu

Functional relevance for associations between osteoporosis and genetic variants

Osteoporosis is characterized by increased bone loss and deterioration of bone microarchitecture, which will lead to reduced bone strength and increased risk of fragility fractures. Previous studies have identified many genetic loci associated with osteoporosis, but functional mechanisms underlying the associations have rarely been explored. In order to explore the potential...

In vitro and in vivo evaluation of docetaxel-loaded stearic acid-modified Bletilla striata polysaccharide copolymer micelles

Bletilla striata polysaccharides (BSPs) have been used in pharmaceutical and biomedical industry, the aim of the present study was to explore a BSPs amphiphilic derivative to overcome its application limit as poorly water-soluble drug carriers due to water-soluble polymers. Stearic acid (SA) was selected as a hydrophobic block to modify B. striata polysaccharides (SA-BSPs...

Relationship between body mass index and depressive symptoms: the “fat and jolly” hypothesis for the middle-aged and elderly in China

authors are grateful to Kun Liu, Hong Li, Dan Li, Zhuo Chen, Li-li Zhang, and Lei-lei Guo. We thank the members of the CHARLS. Funding Collection of the CHARLS datasets used in the current study was

β1/2 or M2/3 Receptors Are Required for Different Gastrointestinal Motility Responses Induced by Acupuncture at Heterotopic or Homotopic Acupoints

Acupuncture at homotopic acupoints or heterotopic acupoints is known to either inhibit or facilitate gastrointestinal motility, depending on the acupoint location. However, little effort has been made to investigate the roles of specific receptors (such as adrenergic and muscarinic acetylcholine receptors) in mediating the effects of acupuncture at heterotopic and homotopic...

Capacity evaluation for general practitioners in Pudong new area of Shanghai: an empirical study

Background Building highly qualified General Practitioners (GPs) is key to the development of primary health care. It’s therefore urgent to ensure the GPs’ quality service under the background of the new round of health care system reforms in China. A new model of GP qualification examination was originally implemented in Pudong New Area of Shanghai, China, which aimed to...

Rapid increase of scrub typhus incidence in Guangzhou, southern China, 2006―2014

Background In the last decade, scrub typhus (ST) has been emerging or re-emerging in some areas of Asia, including Guangzhou, one of the most affected endemic areas of ST in China. Methods Based on the data on all cases reported in Guangzhou from 2006 to 2014, we characterized the epidemiological features, and identified environmental determinants for the spatial distribution of...

Upregulation of microRNA-96 and its oncogenic functions by targeting CDKN1A in bladder cancer

Background Genome-wide miRNA expression profile has identified microRNA (miR)-96 as one of upregulated miRNAs in clinical bladder cancer (BC) tissues compared to normal bladder tissues. The aim of this study was to confirm the expression pattern of miR-96 in BC tissues and to investigate its involvement in carcinogenesis. Methods Quantitative real-time PCR was performed to detect...

The Relationship between Post-Traumatic Symptoms, Parenting Style, and Resilience among Adolescents in Liaoning, China: A Cross-Sectional Study

Background In China, a growing number of adolescents have experienced traumatic events that have resulted in PTSD (post-traumatic stress disorder). Post-traumatic symptoms are common psychological problems in adolescents who have experienced traumatic events. However, existing studies tend to focus on the factors influencing PTSD, such as the response styles and social support...

COGNITIVE SHORTCUTS AND NEW VENTURE TEAM FORMATION: UNDERSTANDING THE IMPACT THAT CONTEXTUAL FACTORS HAVE ON FOUNDING VALUABLE TEAMS (SUMMARY)

Miller 4 Douglas R. Miller, University of North Carolina-Wilmington, USA David S. Noack, Weber State University, USA Kun Liu, Wayne State University , USA - Miller et al.: IMPACT THAT CONTEXTUAL FACTORS

Genome-Scale Transcriptome Analysis in Response to Nitric Oxide in Birch Cells: Implications of the Triterpene Biosynthetic Pathway

Evidence supporting nitric oxide (NO) as a mediator of plant biochemistry continues to grow, but its functions at the molecular level remains poorly understood and, in some cases, controversial. To study the role of NO at the transcriptional level in Betula platyphylla cells, we conducted a genome-scale transcriptome analysis of these cells. The transcriptome of untreated birch...

Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

Sobhika Agarwala Sandra Duquesne Kun Liu Anton Boehm Lin Grimm Sandra Link Sabine König Stefan Eimer Olaf Ronneberger Virginie Lecaudey This PDF is the version of the article that was accepted for

The siRNA cocktail targeting VEGF and HER2 inhibition on the proliferation and induced apoptosis of gastric cancer cell

The aim of this study was to investigate the inhibitory effect of a siRNA cocktail targeting Vascular endothelial growth factor (VEGF) and Human epidermal growth factor receptor 2 (HER2) on cell proliferation, induced apoptosis and the expression of VEGF and HER2 in human gastric carcinoma cell. The silencing rate of pre-designed siRNAs that targeted VEGF and HER2 was detected by...

Effects of a Randomized Intervention to Improve Workplace Social Capital in Community Health Centers in China

Objective To examine whether workplace social capital improved after implementing a workplace social capital intervention in community health centers in China. Methods This study was conducted in 20 community health centers of similar size in Jinan of China during 2012–2013. Using the stratified site randomization, 10 centers were randomized into the intervention group; one...

Selection for chloroquine-sensitive Plasmodium falciparum by wild Anopheles arabiensis in Southern Zambia

Background The emergence of parasite drug resistance, especially Plasmodium falciparum, persists as a major obstacle for malaria control and elimination. To develop effective public health containment strategies, a clear understanding of factors that govern the emergence and spread of resistant parasites in the field is important. The current study documents selection for...

The role of chemotherapy and operation on lymphocytes accumulation in peripheral blood obtained from patients with oral squamous cell carcinoma

Jiafeng Zhao Lichun Wu Chunhua Li Kun Liu Guiquan Zhu Jin Chen Chuan Xu Yongcong Cai Jifeng Liu Zhaohui Wang The “Cancer Immunoediting” concept has provided critical insights suggesting dual functions of