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Antimicrobial activity of puffball(Bovistella radicata) and separation of bioactive compounds

Background To test the antimicrobial activity of different extracts and fermentation broth from puffball(Bovistella radicata), the different extracts and fermentation broth of puffball were prepared, the active fraction was investigated by UPLC–UV–MS and semi-preparative chromatograph. Results Through zones of inhibition (ZOI) and minimum inhibitory concentrations (MIC) tests...

Functional analysis of novel SNPs and mutations in human and mouse genomes

Background With the flood of information generated by the new generation of sequencing technologies, more efficient bioinformatics tools are needed for in-depth impact analysis of novel genomic variations. FANS (Functional Analysis of Novel SNPs) was developed to streamline comprehensive but tedious functional analysis steps into a few clicks and to offer a carefully designed...

A novel panel of biomarkers in distinction of small well-differentiated HCC from dysplastic nodules and outcome values

Background Differential diagnosis of high-grade dysplastic nodules (HGDN) and well-differentiated hepatocellular carcinoma (WDHCC) represents a challenge to experienced hepatic clinicians, radiologists and hepatopathologists. Methods The expression profiles of aminoacylase-1 (ACY1), sequestosome-1 (SQSTM1) and glypican-3 (GPC3) in low-grade dysplastic nodules (LGDN), HGDN and...

Regulation of HSP27 on NF-κB pathway activation may be involved in metastatic hepatocellular carcinoma cells apoptosis

Background During the process of metastasis, cells are subjected to various apoptotic stimuli. Aberrant expression of apoptotic regulators often contribute to cell metastasis. Heat shock protein 27(HSP27) is confirmed as an apoptosis regulator, but its antiapoptotic mechanism in metastatic hepatocellular carcinoma (HCC) cells remains unclear. Methods Levels of HSP27 protein and...

A comprehensive microRNA expression profile of the backfat tissue from castrated and intact full-sib pair male pigs

Wang 1 Cheng-Kun Liu 0 Mei-Ying Fang 0 0 Department of Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, MOA Laboratory of Animal Genetics and Breeding, College of Animal

A first generation BAC-based physical map of the half-smooth tongue sole (Cynoglossus semilaevis) genome

Background Half-smooth tongue sole (Cynoglossus semilaevis Günther) has been exploited as a commercially important cultured marine flatfish, and female grows 2–3 times faster than male. Genetic studies, especially on the chromosomal sex-determining system of this species, have been carried out in the last decade. Although the genome of half-smooth tongue sole was relatively small...

Irregular transcriptome reprogramming probably causes thec developmental failure of embryos produced by interspecies somatic cell nuclear transfer between the Przewalski’s gazelle and the bovine

Background Interspecies somatic cell nuclear transfer (iSCNT) has been regarded as a potential alternative for rescuing highly endangered species and can be used as a model for studying nuclear–cytoplasmic interactions. However, iSCNT embryos often fail to produce viable offspring. The alterations in normal molecular mechanisms contributing to extremely poor development are for...

Rapid increase of scrub typhus incidence in Guangzhou, southern China, 2006―2014

Background In the last decade, scrub typhus (ST) has been emerging or re-emerging in some areas of Asia, including Guangzhou, one of the most affected endemic areas of ST in China. Methods Based on the data on all cases reported in Guangzhou from 2006 to 2014, we characterized the epidemiological features, and identified environmental determinants for the spatial distribution of...

Relationship between body mass index and depressive symptoms: the “fat and jolly” hypothesis for the middle-aged and elderly in China

authors are grateful to Kun Liu, Hong Li, Dan Li, Zhuo Chen, Li-li Zhang, and Lei-lei Guo. We thank the members of the CHARLS. Funding Collection of the CHARLS datasets used in the current study was

Peking Opera and Grotowski's Concept of "Poor Theatre"

In his article "Peking Opera and Grotowski's Concept of 'Poor Theater'" Yao-kun Liu presents a comparative study of Peking opera and Western theater with special attention to Grotowski's concept ... ©Purdue University Article 6 Yao-Kun Liu Whitireia Polytechnic 0 0 Thi s document has been made available through Purdue e-Pubs, a service of the Purdue University Libraries. Please contact Dedicated to

Upregulation of microRNA-96 and its oncogenic functions by targeting CDKN1A in bladder cancer

Background Genome-wide miRNA expression profile has identified microRNA (miR)-96 as one of upregulated miRNAs in clinical bladder cancer (BC) tissues compared to normal bladder tissues. The aim of this study was to confirm the expression pattern of miR-96 in BC tissues and to investigate its involvement in carcinogenesis. Methods Quantitative real-time PCR was performed to detect...

Case-Fatality Ratio and Effectiveness of Ribavirin Therapy Among Hospitalized Patients in China Who Had Severe Fever With Thrombocytopenia Syndrome

Background. The wide distribution and high case-fatality ratio of severe fever with thrombocytopenia syndrome (SFTS) have made it a significant public health problem. This study was designed to identify the predictors of fatal outcomes and to evaluate the effectiveness of antiviral therapy in treating SFTS virus (SFTSV)–infected patients. Methods. A cross-sectional study was...

Suppression of growth of highly-metastatic human breast cancer cells by norcantharidin and its mechanisms of action

Erratum to: Cytotechnology DOI 10.1007/s10616-009-9210-3In the original version of this article, in the “Materials and methods” section, under the subsection “Animal experimentation and preparation of sera from NCTD-treated rabbits”, the third sentence currently reads:‘NCTD was given via the intravenous injection to the rabbits once daily at a dose of 10 mg mL−1 100 g−1 body...

COGNITIVE SHORTCUTS AND NEW VENTURE TEAM FORMATION: UNDERSTANDING THE IMPACT THAT CONTEXTUAL FACTORS HAVE ON FOUNDING VALUABLE TEAMS (SUMMARY)

Miller 4 Douglas R. Miller, University of North Carolina-Wilmington, USA David S. Noack, Weber State University, USA Kun Liu, Wayne State University , USA - Miller et al.: IMPACT THAT CONTEXTUAL FACTORS

PROPERTY RIGHTS, DEPENDENCE ON TRANSACTION PARTNERS, AND FIRM VALUATION: WHO APPROPRIATES VALUE? (INTERACTIVE PAPER)

A key issue gaining attention in the field of entrepreneurship is answering the question of who will appropriate the rents associated with entrepreneurial activity. While entrepreneurs may expend substantial resources to pursue an opportunity, others may be able to appropriate value if the entrepreneurs have not established protections. For example, a key supplier who provides a...

INFORMATION DISCLOSURE AND IPO VALUATION: WHAT KINDS OF INFORMATION MATTER AND IS MORE INFORMATION ALWAYS BETTER?

University, USA Fariss Mousa, Washington State University, USA Kun Liu, Washington State University , USA Daeil Nam Recommended Citation Nam, Daeil; Arthurs, Jonathan D.; Nielsen, Marsha; Mousa, Fariss; and

FOUNDERS, GOVERNANCE, AND FIRM VALUATION: DOES THE MARKET PERCEIVE PSYCHOLOGICAL OWNERSHIP?

We examine the impact of the governance in entrepreneurial firms at the time of the IPO focusing on market valuation based on whether the founder is still with the company. Using agency theory to explain the governance devices (and their purpose), we probe their impact on firm valuation. We develop hypotheses using concepts from psychological ownership to explain why the devices...