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Search: authors:"L. S. Pilowsky"

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Probing Cortical Sites of Antipsychotic Drug Action with in vivo Receptor Imaging

Imaging receptors using radioactive ligands has allowed direct determination of the sites of action of antipsychotic drugs. Initial studies relating antipsychotic drug efficacy to action at striatal dopamine D2-like receptors have recently been undermined. Developments in imaging extrastriatal dopamine D2-like receptors suggest rather that antagonism of these receptors in the...