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Into the Bowels of Depression: Unravelling Medical Symptoms Associated with Depression by Applying Machine-Learning Techniques to a Community Based Population Sample

Learning for Assistive Technologies: 45. 18. Joanna F Dipnall JAP , Michael Berk , Lana J Williams , Seetal Dodd,Felice, N Jacka DM ( 2016 ) Why so GLUMM? Detecting depression clusters through Graphing

Fusing Data Mining, Machine Learning and Traditional Statistics to Detect Biomarkers Associated with Depression

Lana J Williams is supported by a NHMRC Career Methods Atheoretical large-scale data mining techniques using machine learning algorithms have promise in the analysis of large epidemiological datasets

Life Satisfaction and Morbidity among Postmenopausal Women

Objective To investigate associations between morbidity and global life satisfaction in postmenopausal women taking into account type and number of diseases. Materials and Methods A total of 11,084 women (age range 57–66 years) from a population-based cohort of Finnish women (OSTPRE Study) responded to a postal enquiry in 1999. Life satisfaction was measured with a 4-item scale. ...

Statin use and risk of depression: a Swedish national cohort study

Background Statin medications, used to prevent heart disease by reducing cholesterol, also reduce inflammation and protect against oxidative damage. As inflammation and oxidative stress occur in depression, there is interest in their potential to reduce depression risk. We investigated whether use of statin medications was associated with a change in the risk of developing ...

Excessive Daytime Sleepiness and Body Composition: A Population-Based Study of Adults

Background Excessive daytime sleepiness (EDS) is often associated with increased adiposity, particularly when assessed in the context of samples of sleep-disordered patients; however, it is unclear if this relationship is sustained among non-clinical, population-based cohorts. This study aimed to investigate the relationship between EDS and a number of body composition markers ...

Psychiatric disorders, psychotropic medication use and falls among women: an observational study

Background Psychotropic agents known to cause sedation are associated with an increased risk of falls, but the role of psychiatric illness as an independent risk factor for falls is not clear. Thus, this study aimed to investigate the association between psychiatric disorders, psychotropic medication use and falls risk. Methods This study examined data collected from 1062 women ...

Gastro oesophageal reflux disease (GORD)-related symptoms and its association with mood and anxiety disorders and psychological symptomology: a population-based study in women

. Lana J Williams has received Grant/Research support from Eli Lilly, Pfizer, The University of Melbourne, Deakin University and the NHMRC. Authors contributions LS and ALS took part in the conception and

The impact of statins on psychological wellbeing: a systematic review and meta-analysis

Background Cholesterol-lowering medications such as statins have anti-inflammatory and antioxidant properties, which may be beneficial for treating depression and improving mood. However, evidence regarding their effects remains inconsistent, with some studies reporting links to mood disturbances. We aimed to conduct a meta-analysis to determine the impact of statins on ...

The association between diet quality, dietary patterns and depression in adults: a systematic review

and depression, further research is urgently required. Additional file Additional file 1: PRISMA 2009 Checklist. Competing interests Lana J Williams has received Grant/Research support from Eli Lilly ... analysis and critically revised the manuscript, and read and approved the final manuscript. Acknowledgements Lana J Williams is the recipient of an Alfred Deakin Postdoctoral Fellowship. Adrienne O’Neil is

Physical comorbidities in men with mood and anxiety disorders: a population-based study

, Sanofi Synthelabo, Solvay and Wyeth. Lana J Williams has received Grant/Research support from Eli Lilly, Pfizer, The University of Melbourne, Deakin University and the NHMRC. Authors contributions LS and

So depression is an inflammatory disease, but where does the inflammation come from?

Background We now know that depression is associated with a chronic, low-grade inflammatory response and activation of cell-mediated immunity, as well as activation of the compensatory anti-inflammatory reflex system. It is similarly accompanied by increased oxidative and nitrosative stress (O these include psychosocial stressors, poor diet, physical inactivity, obesity, smoking, ...