Advanced search    

Search: authors:"Lei Li"

209 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Myeloperoxidase mediated HDL oxidation and HDL proteome changes do not contribute to dysfunctional HDL in Chinese subjects with coronary artery disease

Vachaparampil Mathew, Haiyi Yu, Lei Li, Liyun He, Wei Gao, Xiaodan Liu, Yanhong Guo, Jaeman Byun, Jifeng Zhang, Y. Eugene Chen. Formal analysis: Guisong Wang, Anna Vachaparampil Mathew, Haiyi Yu, Lei Li, Liyun ... . 13 / 17 Methodology: Lei Li, Yanhong Guo, Jaeman Byun. Project administration: Guisong Wang, Anna Vachaparampil Mathew, Haiyi Yu, Y. Eugene Chen, Subramaniam Pennathur. Resources: Guisong Wang

ERK inhibition promotes neuroectodermal precursor commitment by blocking self-renewal and primitive streak formation of the epiblast

Background Pluripotent stem cells hold great promise for regenerative medicine. However, before clinical application, reproducible protocols for pluripotent stem cell differentiation should be established. Extracellular signal-regulated protein kinase (ERK) signaling plays a central role for the self-renewal of epiblast stem cells (EpiSCs), but its role for subsequent germ layer...

The dose of HBV genome contained plasmid has a great impact on HBV persistence in hydrodynamic injection mouse model

Hydrodynamic injection (HI) of hepatitis B virus (HBV) mouse model is an useful tool for HBV related research in vivo. However, only 40% of C57/BL6 mice injected with 10 μg HBV genome contained plasmid (pAAV-HBV1.2), serum HBsAg more than 6 months and none of the BALB/c mice injected with 10 μg pAAV-HBV1.2 plasmid DNA, serum HBsAg positive more than 4 weeks in the previous study...

Lactate dehydrogenase and creatine kinase as poor prognostic factors in lung cancer: A retrospective observational study

: Huairong Tang, Weimin Li, Li Zhang. Data curation: Lei Liu, Ying He, Ge Ge, Lei Li, Ping Zhou, Yihan Zhu, Yan Huang. Formal analysis: Lei Liu. Investigation: Ying He. Methodology: Lei Liu, Lei Li, Ping

GnRH-mediated olfactory and visual inputs promote mating-like behaviors in male zebrafish

The engagement of sexual behaviors is regulated by a number of factors which include gene expression, hormone circulation, and multi-sensory information integration. In zebrafish, when a male and a female are placed in the same container, they show mating-like behaviors regardless of whether they are kept together or separated by a net. No mating-like behaviors are observed when...

Association of Apolipoprotein C3 Genetic Polymorphisms with the Risk of Ischemic Stroke in the Northern Chinese Han Population

The apolipoprotein C3 (APOC3) gene, which is a member of the APOA1/C3/A4/A5 gene cluster, plays a crucial role in lipid metabolism. Dyslipidemia is an important risk factor for ischemic stroke. In the present study, we performed a hospital-based case—control study of 895 ischemic stroke patients and 883 control subjects to examine the effects of four APOC3 single nucleotide...

Assessment of the toxicity of crude oil in Sinonovacula constricta clams

This study is aimed at investigating the toxic effects on clams (Sinonovacula constricta) exposed to selected concentrations of individual crude oil: water accommodated fraction (WAF) and chemically enhanced (or dispersed) WAF (CEWAF). For this purpose, a study was performed on clams exposed to 0.04 mg L-1 and 0.01 mg L-1 WAF and CEWAF for 15 days, using parameters of antioxidant...

Initial response of fish trophic niche to hydrological alteration in the upstream of Three Gorges Dam

Introduction Damming is one of the dramatic impacts to river food webs due to habitat fragmentation and changes in the hydrological regimes. The world’s largest dam, the Three Gorges Dam (TGD), has been constructed in the middle of Yangtze River since 2003. The objective of this study was to understand the effects of altered hydrological regime on the trophic structure of fish...

Tetrandrine inhibits migration and invasion of human renal cell carcinoma by regulating Akt/NF-κB/MMP-9 signaling

Renal cell carcinoma (RCC) is known as one of the most lethal malignancies in the urological system because of its high incidence of metastasis. Tetrandrine (Tet), a traditional Chinese herbal medicine, exerts a potent anti-cancer effect in a variety of cancer cells. However, the anti-metastatic effect of Tet and its possible mechanism in RCC is still unclear. The present study...

An abnormal displacement change during holding period in nanoindentation tests on zirconia dental ceramic

LI 1 Danyu JIANG 1 0 Department of Stomatology, Nanfang Hospital, Southern Medical University , Guangzhou 510515 , China 1 Analysis and Testing Center for Inorganic Materials, the State Key Laboratory

A mesophilic anaerobic digester for treating food waste: process stability and microbial community analysis using pyrosequencing

Background Anaerobic digesters become unstable when operated at a high organi c loading rate (OLR). Investigating the microbial community response to OLR disturbance is helpful for achieving efficient and stable process operation. However, previous studies have only focused on community succession during different process stages. How does community succession influence process...

One-Dimensional Perovskite Manganite Oxide Nanostructures: Recent Developments in Synthesis, Characterization, Transport Properties, and Applications

One-dimensional nanostructures, including nanowires, nanorods, nanotubes, nanofibers, and nanobelts, have promising applications in mesoscopic physics and nanoscale devices. In contrast to other nanostructures, one-dimensional nanostructures can provide unique advantages in investigating the size and dimensionality dependence of the materials’ physical properties, such as...

Characterization of the Sweet Taste Receptor Tas1r2 from an Old World Monkey Species Rhesus Monkey and Species-Dependent Activation of the Monomeric Receptor by an Intense Sweetener Perillartine

Sweet state is a basic physiological sensation of humans and other mammals which is mediated by the broadly acting sweet taste receptor-the heterodimer of Tas1r2 (taste receptor type 1 member 2) and Tas1r3 (taste receptor type 1 member 3). Various sweeteners interact with either Tas1r2 or Tas1r3 and then activate the receptor. In this study, we cloned, expressed and functionally...