[41] also can be considered for the further improvement. Author Contributions Conceptualization: Xiangxiang Zeng. Data curation: Li Liu, Jiangze Du. Formal analysis: Li Liu. Funding acquisition ... : Xiangxiang Zeng. Investigation: Xiangxiang Zeng, Li Liu, Jiangze Du. Project administration: Jiangze Du. Supervision: Xiangxiang Zeng, Xun Wang, Tao Li. Validation: Stephen Leung. Visualization: Xun Wang
The role of inflammation in diabetic retinal amage is well accepted. While a number of cytokines and inflammatory mediators are responsible for these changes, upstream regulators are less well studied. Additionally, the role for these upstream mediators in retinal health is unclear. In this study, we hypothesized that inhibition of high mobility group box 1 (HMGB1) could restore ...
Lan. Writing ± review & editing: Ai-Fen Peng, Zhi-Li Liu. 7 / 8 1. Leeming DJ , Koizumi M , Byrjalsen I , Li B , Qvist P , Tanko LB . The relative use of eight collagenous and noncollagenous markers
Silver nanowires (Ag NWs) are the promising materials to fabricate flexible transparent electrodes, aiming to replace indium tin oxide (ITO) in the next generation of flexible electronics. Herein, a feasible polyvinylpyrrolidone (PVP)-mediated polyol synthesis of Ag NWs with different aspect ratios is demonstrated and high-quality Ag NWs transparent electrodes (NTEs) are fabricated ...
Nuclear tandemly repeated ribosomal RNA genes (18S-5.8S-25S rDNA and 5S rDNA) have been proven to be excellent cytogenetic markers for karyotype analysis of various higher plants by using the fluorescence in situ hybridization (FISH) technique. To illustrate physical mapping of these rDNAs in brown seaweed, Saccharina japonica, chromosomes, an approximately 5400-bp transcription ...
The alternating projection algorithms are easy to implement and effective for large-scale complex optimization problems, such as constrained reconstruction of X-ray computed tomography (CT). A typical method is to use projection onto convex sets (POCS) for data fidelity, nonnegative constraints combined with total variation (TV) minimization (so called TV-POCS) for sparse-view CT ...
: Man-Li Tong, Jian-Jun Niu, Zhi-Liang Ji, Tian-Ci Yang. Data curation: Qiang Zhao, Li-Li Liu, Hui-Lin Zhang. Formal analysis: Qiang Zhao, Xiao-Zhen Zhu, Kun Gao. Funding acquisition: Man-Li Tong, Li ... -Li Liu, Li-Rong Lin, Jian-Jun Niu, Tian-Ci Yang. Investigation: Li-Li Liu. Methodology: Qiang Zhao, Kun Gao, Hui-Lin Zhang, Li-Rong Lin. Project administration: Tian-Ci Yang. Resources: Xiao-Zhen
Large outbreaks of hand, foot, and mouth disease (HFMD) have repeatedly occurred in mainland of China since 2007. In this study, we investigated the epidemiological and aetiological characteristics of HFMD in Shijiazhuang City, one of the biggest northern cities of China. A total of 57,173 clinical HFMD cases, including 911 severe and 32 fatal cases, were reported in Shijiazhuang ...
Background Understanding the mechanisms of drug resistance can facilitate better management of antiretroviral therapy, helping to prevent transmission and decrease the morbidity and mortality of people living with HIV/AIDS. However, there is little data about transmitted drug resistance and acquired drug resistance for HIV/AIDS patients in Shanghai. Methods A retrospective cohort ...
Contributions Conceptualization: Ling-quan Kong. Data curation: Yu-tuan Wu, Xin Li, Zi-li Liu, Zhou Xu, Wei Dai, Ling-quan Kong. 13 / 16 Formal analysis: Yu-tuan Wu, Xin Li, Zi-li Liu, Zhou Xu, Wei Dai, Ling ... -quan Kong. Funding acquisition: Yu-tuan Wu, Ling-quan Kong. Investigation: Yu-tuan Wu, Xin Li, Zi-li Liu. Methodology: Yu-tuan Wu, Zhou Xu, Wei Dai. Project administration: Kai-nan Wu, Ling-quan Kong
Background Random X-chromosome inactivation (rXCI) is important for the maintenance of normal somatic cell functions in female eutherian mammals. The dynamics of X-chromosome inactivation initiation has been widely studied by assessing embryonic stem cell differentiation in vitro. To investigate the phenomenon in vivo, we applied RNA sequencing to single cells from female embryos ...
Purpose The current meta-analysis aimed to summarize the available evidence for the efficacy and serious adverse events (AEs) associated with use of metronomic chemotherapy (MCT) in patients with metastatic breast cancer (MBC). Method Electronic databases (PubMed, EMBASE database, Web of Knowledge, and the Cochrane database) were systematically searched for articles related to the ...
Objective This study aimed to assess the association between perceived social support (PSS) and fatigue and the roles of hope, optimism, general self-efficacy and resilience as mediators or moderators on PSS-fatigue association among Rheumatoid Arthritis (RA) patients in China. Methods A multi-center, cross-sectional study was conducted withinpatients diagnosed with RA in northeast ...
Objective To evaluate the changes in the jaws and the upper airways of unilateral temporomandibular joint ankylosis patients who underwent condylar reconstruction via autogenous coronoid process grafts using cone-beam computed tomography (CBCT). Study design The 27 included patients underwent CBCT examinations at three stages: T0 (within two weeks before surgery), T1 (two weeks ...
Background The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown. The aim of our study was to evaluate the effect of an intraoperative goal-directed fluid restriction (GDFR) strategy on the postoperative outcome of high-risk patients undergoing brain surgery. Methods High-risk patients undergoing brain surgery were ...
Increased risk of developing metabolic syndrome (MetS) has been associated with the circadian clock genes. In this study, we assessed whether 29 circadian clock-related genes (including ADCYAP1, ARNTL, ARNTL2, BHLHE40, CLOCK, CRY1, CRY2, CSNK1D, CSNK1E, GSK3B, HCRTR2, KLF10, NFIL3, NPAS2, NR1D1, NR1D2, PER1, PER2, PER3, REV1, RORA, RORB, RORC, SENP3, SERPINE1, TIMELESS, TIPIN, VIP, ...
Background Cervical spondylosis is a very common disorder and cervical spondylotic radiculopathy (CSR) is the most common form of spinal degenerative disease. Its clinical manifestations focus on pain and numbness of the neck and arm as well as restricted movement of the neck, which greatly affect the patient’s life and work. The orthopedic of traditional Chinese medicine (TCM) ...
Aiming at efficient similarity search, hash functions are designed to embed high-dimensional feature descriptors to low-dimensional binary codes such that similar descriptors will lead to binary codes with a short distance in the Hamming space. It is critical to effectively maintain the intrinsic structure and preserve the original information of data in a hashing algorithm. In ...
We have recently reported that Compound 49b, a novel β-adrenergic receptor agonist, can significantly reduce VEGF levels in retinal endothelial cells (REC) grown in diabetic-like conditions. In this study, we investigated whether Compound 49b could protect the retina under hypoxic conditions using the ischemia-reperfusion (I/R)-induced model in rats, as well REC cultured in hypoxic ...
Properly designed monitoring networks can generate data to understand status and trends of biodiversity, and to assess progress towards conservation targets. However, biodiversity monitoring is often affected by poor sampling design. We proposed an approach to choosing optimized monitoring sites among large areas. Based on comprehensive distribution data of 34,284 vertebrates and ...