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Clinical value of ALU concentration and integrity index for the early diagnosis of ovarian cancer: A retrospective cohort trial

Conceptualization: Chungen Xing, Kai Li. Data curation: Rong Zhang, Wangyang PU, Shuyun Zhang, Li Chen, Weipei Zhu. Formal analysis: Rong Zhang, Wangyang PU, Shuyun Zhang, Li Chen, Weipei Zhu, Li Xiao, Funding ... acquisition: Rong Zhang, Chungen Xing. Investigation: Rong Zhang, Shuyun Zhang, Li Chen, Weipei Zhu. Methodology: Rong Zhang, Wangyang PU, Li Xiao, Kai Li. Resources: Shuyun Zhang, Li Chen, Weipei Zhu

The Role of TLR4 on PGC-1α-Mediated Oxidative Stress in Tubular Cell in Diabetic Kidney Disease

The role and precise mechanism of TLR4 in mitochondria-related oxidative damage and apoptosis of renal tubules in diabetic kidney disease (DKD) remain unclear. We examined the expression of TLR4 in renal biopsy tissues. Db/db diabetic mice and HK-2 cells cultured under high glucose (HG) were used as in vivo and vitro models. Real-time RT-PCR, Western blot, and...

The graduation performance of technology business incubators in China’s three tier cities: the role of incubator funding, technical support, and entrepreneurial mentoring

This study examines the effects of technology business incubator (TBI)’s funding, technical support and entrepreneurial mentoring on the graduation performance of new technology-based firms in China’s three tier cities. Using a new dataset on all TBIs and incubated new technology-based firms from government surveys conducted over five consecutive years from 2009 to 2013 combined...

The Single Nucleotide Polymorphism rs1014290 of the SLC2A9 Gene Is Associated with Uric Acid Metabolism in Parkinson’s Disease

Individuals with Parkinson’s disease (PD) have lower uric acid levels than those without PD, and the CC genotype and C minor allele of a single nucleotide polymorphism (SNP), rs1014290 of SLC2A9, are associated with lower uric acid levels. We investigated the association of rs1014290 with uric acid metabolism in a cohort of PD cases (220) and controls (110) in a Han Chinese...

Conditional removal of the canonical TGF-β1 signaling delays condylar cartilage degeneration induced by a partial discectomy in mice

Recent emerging data indicate that the increase in the expression and activity of the transforming growth factor beta 1 (Tgf-β1) signaling may have detrimental effect to mature articular cartilage of knee joints. However, there is no information about whether or not this is the case in condylar cartilages. The objective of this study is to investigate the protein expression and...

Consensus of Multiagent Networks with Intermittent Interaction and Directed Topology

400067, China Received 24 May 2014; Revised 22 July 2014; Accepted 22 July 2014; Published 12 August 2014 Academic Editor: Chuandong Li Copyright © 2014 Li Xiao. This is an open access article

Analysis of the tonsillar microbiome in young adults with sore throat reveals a high relative abundance of Fusobacterium necrophorum with low diversity

, Arthur H. Totten, Carlos A. Estrada. Funding acquisition: T. Prescott Atkinson. Investigation: T. Prescott Atkinson, Michael B. Faircloth, Ken B. Waites. Methodology: Robert M. Centor, Li Xiao, Casey D ... . Morrow, Ken B. Waites. Software: Li Xiao, Casey D. Morrow. Supervision: T. Prescott Atkinson, Robert M. Centor, Li Xiao, Michael B. Faircloth, Ken B. Waites. Writing ± original draft: T. Prescott

From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells

From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells Li Xiao,1 Masanori Nasu2 1Department of Pharmacology, 2Research Center, The

Exo70 is an independent prognostic factor in colon cancer

(3502Z20159013), and the Fundamental Research Funds for the Central Universities (20720150058). Author information Author notes Li Xiao and Kaifeng Zheng contributed equally to this work. AffiliationsCancer ... , Xiaoting Hong, Yan-yan Zhan & Tianhui HuDepartment of Oncology, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, 361004, Fujian Province, P.R. ChinaLi Xiao & Xia Lv AuthorsSearch for Li Xiao

Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics

Extensive efforts have been directed at the discovery, investigation and clinical monitoring of targeted therapeutics. These efforts may be facilitated by the convenient access of the genetic, proteomic, interactive and other aspects of the therapeutic targets. Here, we describe an update of the Therapeutic target database (TTD) previously featured in NAR. This update includes...

Association between alcohol consumption and the risk of incident type 2 diabetes: a systematic review and dose-response meta-analysis

Background: Previous cohort studies have shown that moderate alcohol consumption was associated with a lower risk of type 2 diabetes (T2D). However, whether these associations differ according to the characteristics of patients with T2D remains controversial.

PMMA interlayer-modulated memory effects by space charge polarization in resistive switching based on CuSCN-nanopyramids/ZnO-nanorods p-n heterojunction

Materials Science and Engineering, Nanchang University, Jiangxi 330031, P. R. ChinaBaochang Cheng, Jie Zhao, Li Xiao, Qiangsheng Cai, Rui Guo, Yanhe Xiao & Shuijin LeiNanoscale Science and Technology ... Zhao in:Nature Research journals • PubMed • Google ScholarSearch for Li Xiao in:Nature Research journals • PubMed • Google ScholarSearch for Qiangsheng Cai in:Nature Research journals • PubMed • Google

Exploration of pathological prediction of chronic kidney diseases by a novel theory of bi-directional probability

AffiliationsDepartment of Nephrology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, ChinaYuan Yang, Min Luo, Li Xiao, Xue-jing Zhu, Chang Wang, Xiao Fu, Shu-guang Yuan, Hong Liu, Zheng ... in:Nature Research journals • PubMed • Google ScholarSearch for Li Xiao in:Nature Research journals • PubMed • Google ScholarSearch for Xue-jing Zhu in:Nature Research journals • PubMed • Google ScholarSearch

Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase

, Marc Labroli, Li Xiao, Giovanna Scapin, Nichole Buist, Christopher M. Tan, Todd A. Black, Terry Roemer. Zuck, Stacia Kargman, Li Xiao, Kristine Devito. Data curation: Ronald E. Painter, Brad Sherborne ... Wiltsie, Brad Sherborne, Xinwei Sher, Paul Mann, Paul Zuck, Li Xiao, Giovanna Scapin, Scott Salowe, KrisMethodology: Scott S. Walker, Marc Labroli, Paul Mann, Scott Salowe, Nichole Buist. Project

NLO QCD + NLO EW corrections to WZZ productions with leptonic decays at the LHC

Precision tests of the Standard Model (SM) require not only accurate experiments, but also precise and reliable theoretical predictions. Triple vector boson production provides a unique opportunity to investigate the quartic gauge couplings and check the validity of the gauge principle in the SM. Since the tree-level predictions alone are inadequate to meet this demand, the next...


F RO N T I E R S O F E N T R E P R E N E U R S H I P R E S E A RC H Li Xiao 0 0 This Paper is brought to you for free and open access by the Entrepreneurship at Babson at Digital Knowledge at

Prediction of cancer progression in a group of 73 gastric cancer patients by circulating cell-free DNA

Background Circulating cell-free DNA (ccf-DNA) in plasma may contain both specific and non-specific of tumor markers. The concentration and integrity of ccf-DNA may be clinical useful for detecting and predicting cancer progression. Methods Plasma samples from 40 healthy controls and 73 patients with gastric cancers (two stage 0, 17 stage I, 11 stage II, 33 stage III, and 10...

Comment on Paolo et al. “Effect of pulsed electromagnetic field therapy in patients undergoing total knee arthroplasty: a randomized controlled trial”

Shengtan Zhang Li Xiao Li Chen Xinyu Lan Jishan Lan 0 ) Department of Anesthesiology, Cangzhou Hospital of Integrated Traditional and Western Medicine of Hebei Province , Cangzhou 061001, Hebei Prov