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MicroRNA 375 modulates hyperglycemia-induced enteric glial cell apoptosis and Diabetes-induced gastrointestinal dysfunction by targeting Pdk1 and repressing PI3K/Akt pathway

Research journals • PubMed • Google Scholar Search for Fuqian He in:Nature Research journals • PubMed • Google Scholar Search for Li Zhang in:Nature Research journals • PubMed • Google Scholar Search for ... Liu analyzed the data and wrote the paper; Fuqian He & Li Zhang contributed to the gene transfection; Kun Yang, Huan Yu & Jinqiu Zhou helped to isolate the colon myenteric plexus and immunofluorescence

Data-Driven Hybrid Internal Temperature Estimation Approach for Battery Thermal Management

Temperature is a crucial state to guarantee the reliability and safety of a battery during operation. The ability to estimate battery temperature, especially the internal temperature, is of paramount importance to the battery management system for monitoring and thermal control purposes. In this paper, a data-driven approach combining the RBF neural network (NN) and the extended...

Curcumin alleviates pain and improves cognitive impairment in a rat model of cobra venom-induced trigeminal neuralgia

Curcumin alleviates pain and improves cognitive impairment in a rat model of cobra venom-induced trigeminal neuralgia Li Zhang,1 Xinli Ding,2 Zhe Wu,3 Min Wang,1 Ming Tian1 1Department of

Fuzzy rule-based systems for recognition-intensive classification in granular computing context

In traditional machine learning, classification is typically undertaken in the way of discriminative learning using probabilistic approaches, i.e. learning a classifier that discriminates one class from other classes. The above learning strategy is mainly due to the assumption that different classes are mutually exclusive and each instance is clear-cut. However, the above...

A Parameter Adaptive Genetic Algorithm Based Service Compositions

MATEC Web of Conferences A Parameter Compositions Huizhou Yang 0 Li Zhang 0 0 School of Computer Science, Xi'an ShiYou University , 710065, Shaanxi , China How to select and combine many services

Corrigendum to “Pharmacological Basis for Use of Selaginella moellendorffii in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition”

Zhang,1,2 Guang-rui Deng,1,2 and Juan Li1,3 1Key Laboratory of Ministry of Education on Traditional Chinese Medicine Resource and Compound Prescription and College of Pharmacy, Hubei University of

Higher baseline viral diversity correlates with lower HBsAg decline following PEGylated interferon-alpha therapy in patients with HBeAg-positive chronic hepatitis B

Higher baseline viral diversity correlates with lower HBsAg decline following PEGylated interferon-alpha therapy in patients with HBeAg-positive chronic hepatitis B Hu Li, Li Zhang, Hong Ren, Peng Hu ... Zhang 0 Hong Ren 0 Peng Hu 0 0 Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases, Ministry of Education, Institute for Viral Hepatitis, The Second Affiliated

The Associations between Toll-Like Receptor 9 Gene Polymorphisms and Cervical Cancer Susceptibility

This meta-analysis systematically reviews the association between Toll-like receptor 9 polymorphisms and the risk of cervical cancer. Case-control studies focused on the association were collected from the PubMed, Web of Science, Cochrane Library, Embase, MEDLINE, CNKI, VIP, and Wanfang databases from inception to July 2017. We screened the studies and assessed the methodological...

A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples

A facile, green, and high-output hydrothermal synthesis was proposed for the fabrication of highly fluorescent nitrogen-doped carbon quantum dots (N-doped CDs). The nitrogen content in N-doped CDs reached 19.2% and demonstrated strong blue fluorescence emission was obtained with fluorescence quantum yield (QY) of up to 32.9%, which exhibit high fluorescence quantum yield, high...

Puerarin Mitigates Diabetic Hepatic Steatosis and Fibrosis by Inhibiting TGF-β Signaling Pathway Activation in Type 2 Diabetic Rats

Chunyang Xu,2,4 Xi Chen,2 Chenge Liu,2 Xiaobo Wang,2,3 Li Zhang,1,2 and Guanhua Du1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese ... University of Commerce, Harbin 510006, China Correspondence should be addressed to Li Zhang; nc.ca.mmi@ilgnahz and Guanhua Du; nc.ca.mmi@hgud Received 12 October 2017; Revised 4 March 2018; Accepted 1 April

A cross-sectional study: serum CCL3/MIP-1α levels may reflect lumbar intervertebral disk degeneration in Han Chinese people

A cross-sectional study: serum CCL3/MIP-1alpha levels may reflect lumbar intervertebral disk degeneration in Han Chinese people Yi-Li Zhang,1,2,* Bei Li,1,2,* Zeng-Huan Zhou1 1School of Public Health

Correction to: A holistic view of cancer bioenergetics: mitochondrial function and respiration play fundamental roles in the development and progression of diverse tumors

Zhang 0 0 Department of Biological Sciences, University of Texas at Dallas , Mail Stop RL11, 800 W, Campbell Road, Richardson, TX 75080 , USA Texas) Grant RP160617. - In this Correction, the authors

Computational Analysis of Artimisinin Derivatives on the Antitumor Activities

The study on antitumor activities of artemisinin and its derivatives has been closely focused on in recent years. Herein, 2D and 3D QSAR analysis was performed on the basis of a series of artemisinin derivatives with known bioactivities against the non-small-cell lung adenocarcinoma A549 cells. Four QSAR models were successfully established by CoMSIA, CoMFA, topomer CoMFA and...

Fabrication of ultrasmall WS2 quantum dots-coated periodic mesoporous organosilica nanoparticles for intracellular drug delivery and synergistic chemo-photothermal therapy

Fabrication of ultrasmall WS2 quantum dots-coated periodic mesoporous organosilica nanoparticles for intracellular drug delivery and synergistic chemo-photothermal therapy Wenyun Liao,1 Li Zhang,1

Interface-Dependent Effective Mobility in Graphene Field-Effect Transistors

By pretreating the substrate of a graphene field-effect transistor (G-FET), a stable unipolar transfer characteristic, instead of the typical V-shape ambipolar behavior, has been demonstrated. This behavior is achieved through functionalization of the SiO2/Si substrate that changes the SiO2 surface from hydrophilic to hydrophobic, in combination with postdeposition of an Al2O3...

Identification of differentially expressed genes and signaling pathways in ovarian cancer by integrated bioinformatics analysis

Identification of differentially expressed genes and signaling pathways in ovarian cancer by integrated bioinformatics analysis Xiao Yang,1 Shaoming Zhu,2 Li Li,3 Li Zhang,1 Shu Xian,1 Yanqing Wang,1

A comprehensive scoring system in correlation with perioperative airway management for neonatal Pierre Robin Sequence

: Lei Fang. Funding acquisition: Ning Yin. Data curation: Xiaohua Shi, Hongqiang Huang, Li Zhang. Investigation: Xiaohua Shi, Hongqiang Huang, Li Zhang. Methodology: Hongqiang Huang. Project ... administration: Lei Fang. Supervision: Ning Yin. Validation: Li Zhang. Writing ± original draft: Lei Fang. Writing ± review & editing: Ning Yin. 8 / 9 1. Gangopadhyay N , Mendonca DA , Woo AS . Pierre Robin

Microstructure and mechanical properties of a hot-extruded Al-based composite reinforced with core–shell-structured Ti/Al3Ti

An Al-based composite reinforced with core–shell-structured Ti/Al3Ti was fabricated through a powder metallurgy route followed by hot extrusion and was found to exhibit promising mechanical properties. The ultimate tensile strength and elongation of the composite sintered at 620°C for 5 h and extruded at a mass ratio of 12.75:1 reached 304 MPa and 14%, respectively, and its...

Cardiomyocyte differentiation of mesenchymal stem cells from bone marrow: new regulators and its implications

In the past years, cardiac mortality has decreased, but cardiac diseases are still responsible for millions of deaths every year worldwide. Bone-marrow mesenchymal stem cells (BMSCs) transplantation may be a promising therapeutic strategy because of its capacity to differentiate into cardiac cells. Current research indicates that chemical substances, microRNAs, and cytokines have...

Postmastectomy radiotherapy reduces locoregional and disease recurrence in patients with stage II–III triple-negative breast cancer treated with neoadjuvant chemotherapy and mastectomy

,1,2,* Fan Xia,1,2,* Jurui Luo,1,2,* Jinli Ma,1,2 Zhaozhi Yang,1,2 Li Zhang,1,2 Yan Feng,1,2 Zhimin Shao,2,3 Xiaoli Yu,1,2 Xiaomao Guo1,2 1Department of Radiation Oncology, Fudan University Shanghai