Advanced search    

Search: authors:"Lih-Chu Chiou"

3 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Conditioned place preference training prevents hippocampal depotentiation in an orexin-dependent manner

Long-term potentiation (LTP) is well recognized as a cellular-correlated synaptic plasticity of learning and memory. However, its reversal forms of synaptic plasticity, depotentiation, is less studied and its association with behaviors is also far from clear. Previously, we have shown that nanomolar orexin A can prevent the depotentiation induced by low frequency stimulation (LFS...

Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons

• Google ScholarSearch for Ken Mackie in:Nature Research journals • PubMed • Google ScholarSearch for Andreas Zimmer in:Nature Research journals • PubMed • Google ScholarSearch for Lih-Chu Chiou in:Nature ... Lih-Chu Chiou. Supplementary information PDF files1.Supplementary Information Supplementary Figures 1-5, Supplementary Table 1 Rights and permissions This work is licensed under a Creative

Differential Pharmacological Actions of Methadone and Buprenorphine in Human Embryonic Kidney 293 Cells Coexpressing Human μ-Opioid and Opioid Receptor-Like 1 Receptors

Methadone and buprenorphine are used in maintenance therapy for heroin addicts. In this study, we compared their effects on adenylate cyclase (AC) activity in human embryonic kidney (HEK) 293 cells stably overexpressing human μ-opioid receptor (MOR) and nociceptin/opioid receptor-like 1 receptor (ORL1) simultaneously. After acute exposure, methadone inhibited AC activity; however...