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Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability

). Author Contributions Conceptualization: LiLi Wang, Rodney F. Minchin, Neville J. Butcher. Data curation: LiLi Wang, Neville J. Butcher. Formal analysis: Rodney F. Minchin. Funding acquisition: Rodney F ... . Minchin. Methodology: LiLi Wang. Project administration: Neville J. Butcher. Supervision: Rodney F. Minchin, Neville J. Butcher. Writing ± original draft: LiLi Wang. Writing ± review & editing: Rodney

Network structure of scientific collaborations between China and the EU member states

Collaborations between China and the European Union (EU) member states involve not only connections between China and individual countries, but also interactions between the different EU member states, the latter of which is due also to the influence exerted by the EU’s integration strategy. The complex linkages between China and the EU28, as well as among the 28 EU member states...

Steps to achieve quantitative measurements of microRNA using two step droplet digital PCR

: Erica V. Stein, Natalia Farkas, Erica L. Romsos. Methodology: Erica V. Stein, David L. Duewer, Natalia Farkas, Erica L. Romsos, Lili Wang, Kenneth D. Cole. Project administration: Erica V. Stein ... . Resources: Lili Wang, Kenneth D. Cole. 24 / 26 Supervision: Lili Wang, Kenneth D. Cole. Validation: Erica V. Stein. Visualization: David L. Duewer. Writing ± original draft: Erica V. Stein. Writing

Face-body integration of intense emotional expressions of victory and defeat

Human facial expressions can be recognized rapidly and effortlessly. However, for intense emotions from real life, positive and negative facial expressions are difficult to discriminate and the judgment of facial expressions is biased towards simultaneously perceived body expressions. This study employed event-related potentials (ERPs) to investigate the neural dynamics involved...

Multimorbidity and health-related quality of life (HRQoL) in a nationally representative population sample: implications of count versus cluster method for defining multimorbidity on HRQoL

Acknowledgements We gratefully acknowledge the Australian Bureau of Statistics for conducting the survey. Funding Lili Wang was funded by a University of Tasmania/Anhui Medical University PhD Scholarship. The ... authors upon reasonable request and with permission from the Australian Bureau of Statistics. Authors’ contributions Kristy Sanderson conceived of and designed the study. Lili Wang and Kristy Sanderson

Mechanisms for attentional modulation by threatening emotions of fear, anger, and disgust

Appropriately attending to threatening environmental stimuli is evolutionarily adaptive and crucial for survival. This study revealed that nonconscious attentional modulation of disgust has different behavioral and event-related potential (ERP) patterns, as compared to fear and anger. To facilitate its evolutionary purpose of avoidance, disgust first diverts rather than attracts...

Robust stability and -control of uncertain systems with impulsive perturbations

Meng Hu Lili Wang In this paper, the problems of robust stability, stabilization, and H-control for uncertain systems with impulsive perturbations are investigated. The parametric uncertainties are

Multiple periodic solutions in shifts δ± for an impulsive functional dynamic equation on time scales

Meng Hu Lili Wang In this paper, based on the theory of calculus on time scales, by using a multiple fixed point theorem in cones, some criteria are established for the existence and multiplicity

Mining candidate genes associated with powdery mildew resistance in cucumber via super-BSA by specific length amplified fragment (SLAF) sequencing

Background Powdery mildew (PM) is the most common fungal disease of cucumber and other cucurbit crops, while breeding the PM-resistant materials is the effective way to defense this disease, and the recent development of modern genetics and genomics make us aware of that studying the resistance genes is the essential way to breed the PM high-resistance plant. With the ever...

Expression of amphiregulin predicts poor outcome in patients with pancreatic ductal adenocarcinoma

Background The validation of novel diagnostic, prognostic and predictive biomarkers in cancer is crucial for optimizing the choice and efficacy of personalized therapies. The aim of this study was to determine the epidermal growth factor receptor (EGFR), epidermal growth factor receptor variant III (EGFRvIII) and amphiregulin (AREG) protein expression levels and to evaluate the...

Robust stability and H∞-control of uncertain systems with impulsive perturbations

Meng Hu Lili Wang In this paper, the problems of robust stability, stabilization, and H-control for uncertain systems with impulsive perturbations are investigated. The parametric uncertainties are

A New Genetic Diagnostic for Enlarged Vestibular Aqueduct Based on Next-Generation Sequencing

Enlarged vestibular aqueduct (EVA) is one of the most common congenital inner ear malformations and accounts for 1–12% of sensorineural deafness in children and adolescents. Multiple genetic defects contribute to EVA; therefore, early molecular diagnosis is critical for EVA patients to ensure that the most effective treatment strategies are employed. This study explored a new...

The Impact of Perceptual Load on the Non-Conscious Processing of Fearful Faces

Emotional stimuli can be processed without consciousness. In the current study, we used event-related potentials (ERPs) to assess whether perceptual load influences non-conscious processing of fearful facial expressions. Perceptual load was manipulated using a letter search task with the target letter presented at the fixation point, while facial expressions were presented...

Circulating miR-25-3p and miR-451a May Be Potential Biomarkers for the Diagnosis of Papillary Thyroid Carcinoma

Objective There is no effective and reliable biomarker to distinguish benign thyroid nodules from papillary thyroid carcinomas (PTC). This study aimed at examining the levels of plasma miRNAs in patients with PTC or benign nodules to explore the potential miRNA biomarkers for PTC. Patients and Methods Genome-wide plasma miRNA expression profiles were determined by the miRNA...

The Role of Synaptopodin in Membrane Protein Diffusion in the Dendritic Spine Neck

The dynamic exchange of neurotransmitter receptors at synapses relies on their lateral diffusion in the plasma membrane. At synapses located on dendritic spines this process is limited by the geometry of the spine neck that restricts the passage of membrane proteins. Biochemical compartmentalisation of the spine is believed to underlie the input-specificity of excitatory synapses...

Transcriptome and comparative gene expression analysis of Phyllostachys edulis in response to high light

Background Photosynthesis plays a vital role as an energy source for plant metabolism, and its efficiency may be drastically reduced owing to abiotic stresses. Moso bamboo (Phyllostachys edulis), is a renewable and versatile resource with significant ecological and economic value, which encounters high light stress with large amplitude in natural environment. However, the gene...

Different Antibody Response against the Coxsackievirus A16 VP1 Capsid Protein: Specific or Non-Specific

Coxsackievirus A16 (CA16) is one of the major causative agents of hand, foot, and mouth disease worldwide. The non-neutralizing antibody response that targets CA16 VP1 remains poorly elucidated. In the present study, antibody responses against CA16 VP1 in Shanghai blood donors and Shanxi individuals were analyzed by ELISA and inhibitory ELISA using five CA16 VP1 antigens: VP11...

Formation of silacycles via metal-mediated or catalyzed Si-C bond cleavage

Silacycles play a very important role in modern organic chemistry and materials science. Construction of silacyclic skeletons via metal-mediated or catalyzed Si-C bond cleavage has attracted much recent attention. Several interesting and useful synthetic strategies have been reported in the literature. In this review, we have summarized recent developments on metal-mediated or...

Copy number variations in 119 Chinese children with idiopathic short stature identified by the custom genome-wide microarray

Background Idiopathic short stature (ISS) refers to short stature with no evident etiologies. The custom genome-wide microarray specifically designed to cover height-related genes may be helpful to detect copy number variations (CNVs) in ISS patients, which may be missed by the general microarray. The aim of the study was to validate the applicability of the custom microarray and...