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103 papers found.
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A Novel Kinematic Parameters Identification Method for Articulated Arm Coordinate Measuring Machines Using Repeatability and Scaling Factor

June 2018; Published 15 July 2018 Academic Editor: Salvatore Strano Copyright © 2018 Lin Cheng et al. This is an open access article distributed under the Creative Commons Attribution License, which

Ezh2 does not mediate retinal ganglion cell homeostasis or their susceptibility to injury

and Jonatan Olafsson for help with RGC counts. Author Contributions Conceptualization: Dong Feng Chen. Data curation: Lin Cheng, Lucy J. Wong, Naihong Yan, Richard C. Han, Honghua Yu, Chenying Guo ... , Khulan Batsuuri, Aniket Zinzuwadia, Ryan Guan, Kin-Sang Cho. Formal analysis: Lin Cheng, Lucy J. Wong, Naihong Yan, Richard C. Han, Khulan Batsuuri, Aniket Zinzuwadia, Ryan Guan, Kin-Sang Cho, Dong Feng

Identification of Common Genes Refers to Colorectal Carcinogenesis with Paired Cancer and Noncancer Samples

Colorectal cancer is a malignant tumor which harmed human beings’ health. The aim of this study was to explore common biomarkers associated with colorectal carcinogenesis in paired cancer and noncancer samples. At first, fifty-nine pairs of colorectal cancer and noncancer samples from three gene expression datasets were collected and analyzed. Then, 181 upregulation and 282...

Focus on Mesenchymal Stem Cell-Derived Exosomes: Opportunities and Challenges in Cell-Free Therapy

: Changwon Park Copyright © 2017 Lin Cheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in

A comprehensive overview of exosomes in ovarian cancer: emerging biomarkers and therapeutic strategies

Exosomes are nanoparticles(40-100 nm) secreted by most cells in the body, which can be isolated from several types of extracellular fluids. It has been shown that exosomes play a key role in intercellular communication and in transportation of genetic information. Emerging evidence shows that exosomes are mediators of metastasis in tumour cells, stromal cells and the...

A comprehensive overview of exosomes in ovarian cancer: emerging biomarkers and therapeutic strategies

Exosomes are nanoparticles(40-100 nm) secreted by most cells in the body, which can be isolated from several types of extracellular fluids. It has been shown that exosomes play a key role in intercellular communication and in transportation of genetic information. Emerging evidence shows that exosomes are mediators of metastasis in tumour cells, stromal cells and the...

A comprehensive overview of exosomes in ovarian cancer: emerging biomarkers and therapeutic strategies

Exosomes are nanoparticles(40-100 nm) secreted by most cells in the body, which can be isolated from several types of extracellular fluids. It has been shown that exosomes play a key role in intercellular communication and in transportation of genetic information. Emerging evidence shows that exosomes are mediators of metastasis in tumour cells, stromal cells and the...

Comparison of sentinel lymph node biopsy guided by indocyanine green, blue dye, and their combination in breast cancer patients: a prospective cohort study

study Jiajia Guo 0 Houpu Yang 0 Shu Wang Yingming Cao Miao Liu Fei Xie Peng Liu Bo Zhou Fuzhong Tong Lin Cheng Hongjun Liu Siyuan Wang 0 Equal contributors Peking University People's Hospital Breast

Qualitative insights into the experiences of living with moderate-to-severe lower urinary tract symptoms among community-dwelling ageing males

Ping Suen, Hui Lin Cheng, Simon Kai Wang Yeung, Cypher Ho Au-Yeung, Jillianne Chi Yen Lee, Kathy Kit Ying Ho, Natalie Ming Yan Lau, Cristina Ka Fu Ng, Iris Wai Sze Chan. Formal analysis: Lorna Kwai Ping ... Suen, Hui Lin Cheng, Simon Kai Wang Yeung, Cypher Ho Au-Yeung, Jillianne Chi Yen Lee, Kathy Kit Ying Ho, Natalie Ming Yan Lau, Cristina Ka Fu Ng, Iris Wai Sze Chan. Funding acquisition: Lorna Kwai Ping

Long non-coding RNA tagging and expression manipulation via CRISPR/Cas9-mediated targeted insertion

the future. FOOTNOTES We thank Yuefang Zhang and Shifang Shan for their help in experiments. We also thank members of the entire Qiu lab for their help and suggestions. Tian-Lin Cheng is supported by ... The Knowledge Innovation Program of CAS 2014KIP205, Shanghai Sailing Program 15YF1414200, and NSFC #31600826. Zilong Qiu is supported by NSFC #91432111, #31625013. Tian-Lin Cheng and Zilong Qiu

Evaluating turnaround times for early infant diagnosis samples in Kenya from 2011-2014: A retrospective analysis of HITSystem program data

Wexler, An-Lin Cheng, Brad Gautney, Sarah Finocchario-Kessler, Kathy Goggin, Samoel Khamadi. Project administration: Catherine Wexler, Brad Gautney, Sarah Finocchario-Kessler, . Supervision: Brad Gautney ... , Sarah Finocchario-Kessler, Kathy Goggin, Samoel Khamadi, . Visualization: An-Lin Cheng. Writing ± original draft: Catherine Wexler. Writing ± review & editing: Catherine Wexler, An-Lin Cheng, Brad

Interleukin-35 on B cell and T cell induction and regulation

Interleukin (IL)-35 is a relatively newly discovered member of IL-12 cytokine family that is unique in that it is a dimer formed by two subunits. The review documents the structure, secretion and signal transduction of IL-35, the regulation effect of IL-35 on B cells and T cells as well as the adoptive transfer of IL-35+ regulatory B cells (Breg), therapeutic prospects of...

Editor's Highlight: Periodic Exposure to Smartphone-Mimic Low-Luminance Blue Light Induces Retina Damage Through Bcl-2/BAX-Dependent Apoptosis

Blue light-induced phototoxicity plays an important role in retinal degeneration and might cause damage as a consequence of smartphone dependency. Here, we investigated the effects of periodic exposure to blue light-emitting diode in a cell model and a rat retinal damage model. Retinal pigment epithelium (RPE) cells were subjected to blue light in vitro and the effects of blue...

Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk

Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. Human WW domain-containing oxidoreductase (WWOX) gene has been identified as a tumor suppressor gene in multiple cancers. We hypothesize that genetic variations in WWOX are associated with HCC risk. Methodology/Principal findings Five single-nucleotide polymorphisms (SNPs) of the WWOX...

Cocktail of chemical compounds robustly promoting cell reprogramming protects liver against acute injury

epithelial; TGF-β, transforming growth factor beta; VPA, valproic acid. COMPLIANCE WITH ETHICS GUIDELINES Lin Cheng and Yuewen Tang declare that they have no conflict of interest. All institutional and

Production of high stellar-mass primordial black holes in trapped inflation

Trapped inflation has been proposed to provide a successful inflation with a steep potential. We discuss the formation of primordial black holes in the trapped inflationary scenario. We show that primordial black holes are naturally produced during inflation with a steep trapping potential. In particular, we have given a recipe for an inflaton potential with which particle...

Permanent cardiac pacing in patients with end-stage renal disease undergoing dialysis

Studies investigating the risk of cardiac dysrhythmia warranting permanent pacemaker therapy for end-stage renal disease (ESRD) patients are limited. This study investigated the incidence rate of permanent cardiac pacing in dialysis patients.

Prevalence of Integrase Strand Transfer Inhibitors (INSTI) Resistance Mutations in Taiwan

Antiretroviral therapy containing an integrase strand transfer inhibitor (INSTI) plus two NRTIs has become the recommended treatment for antiretroviral-naive HIV-1-infected patients in the updated guidelines. We aimed to determine the prevalence of INSTI-related mutations in Taiwan. Genotypic resistance assays were performed on plasma from ARV-naïve patients (N = 948), ARV...

Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells

Glioblastoma (GBM) is the most malignant and lethal brain tumor harboring glioma stem cells (GSCs) that promote tumor propagation and therapeutic resistance. GSCs preferentially express several critical cell surface molecules that regulate the pro-survival signaling for maintaining the stem cell-like phenotype. Tetraspanin CD9 has recently been reported as a GSC biomarker that is...

MAGIC Study: Aims, Design and Methods using SystemCHANGE™ to Improve Immunosuppressive Medication Adherence in Adult Kidney Transplant Recipients

Shirley Moore 3 Donna Hathaway 1 An-Lin Cheng 0 Guoqing Chen 5 Kathy Goggin 4 0 School of Nursing and Health Studies, University of Missouri-Kansas City , Health Sciences Building 2407, Kansas City, MO