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Elective high-frequency oscillatory ventilation in preterm infants with respiratory distress syndrome: an individual patient data meta-analysis

Filip Cools 2 Lisa M Askie 1 Martin Offringa 0 for the Prevention of Ventilator Induced Lung Injury collaborative study Group (PreVILIG Collaboration) 0 Department of Pediatric Clinical

Statistical Analysis of Individual Participant Data Meta-Analyses: A Comparison of Methods and Recommendations for Practice

Background Individual participant data (IPD) meta-analyses that obtain “raw” data from studies rather than summary data typically adopt a “two-stage” approach to analysis whereby IPD within trials generate summary measures, which are combined using standard meta-analytical methods. Recently, a range of “one-stage” approaches which combine all individual participant data in a...

NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol

; DSMC: Data and Safety Monitoring Committee. Acknowledgements Members of the NeOProM Collaborative Group who have contributed to the development of this protocol (in alphabetical order): Lisa M Askie

Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study

Cools Lisa M Askie Jeanette M Asselin Sandra A Calvert Sherry E Courtney Carlo Dani David J Durand Neil Marlow Janet L Peacock J Jane Pillow Roger F Soll Ulrich H Thome Patrick Truffert Michael D

The Early Prevention of Obesity in CHildren (EPOCH) Collaboration - an Individual Patient Data Prospective Meta-Analysis

Background Efforts to prevent the development of overweight and obesity have increasingly focused early in the life course as we recognise that both metabolic and behavioural patterns are often established within the first few years of life. Randomised controlled trials (RCTs) of interventions are even more powerful when, with forethought, they are synthesised into an individual...

Repeat prenatal corticosteroid prior to preterm birth: a systematic review and individual participant data meta-analysis for the PRECISE study group (prenatal repeat corticosteroid international IPD study group: assessing the effects using the best level of evidence) - study protocol

Background The aim of this individual participant data (IPD) meta-analysis is to assess whether the effects of repeat prenatal corticosteroid treatment given to women at risk of preterm birth to benefit their babies are modified in a clinically meaningful way by factors related to the women or the trial protocol. Methods/Design The Prenatal Repeat Corticosteroid International IPD...

Inhaled Nitric Oxide in preterm infants: a systematic review and individual patient data meta-analysis

Background Preterm infants requiring assisted ventilation are at significant risk of both pulmonary and cerebral injury. Inhaled Nitric Oxide, an effective therapy for pulmonary hypertension and hypoxic respiratory failure in the full term infant, has also been studied in preterm infants. The most recent Cochrane review of preterm infants includes 11 studies and 3,370...