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Search: authors:"Lisa Seipold"

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In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15

A disintegrin and metalloproteinase 10 (ADAM10) plays a major role in the ectodomain shedding of important surface molecules with physiological and pathological relevance including the amyloid precursor protein (APP), the cellular prion protein, and different cadherins. Despite its therapeutic potential, there is still a considerable lack of knowledge how this protease is...