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Determination of adjusted reference intervals of urinary biomarkers of oxidative stress in healthy adults using GAMLSS models

London Metropolitan University, who is one of the two creators of the GAMLSS method. We thank him for his helpful remarks. Author Contributions Conceptualization: Liliya Chamitava, Lucia Cazzoletti ... . Formal analysis: Liliya Chamitava, Lucia Cazzoletti, Maria E. Zanolin. Funding acquisition: Maria E. Zanolin. Investigation: Andrea Pasini, Valeria Bellisario, Angelo G. Corsico, Morena Nicolis, Mario

Anemia and hemoglobin serum levels are associated with exercise capacity and quality of life in chronic obstructive pulmonary disease

Background Little is known about the relationship between hemoglobin concentrations, functional status and health related quality of life (HRQL) in chronic obstructive pulmonary disease (COPD). Our aim was to investigate the prevalence of anemia and the association of hemoglobin with shortness of breath, exercise capacity, muscle strength and HRQL, in COPD patients. Methods A...

The gender, age and risk factor distribution differs in self-reported allergic and non-allergic rhinitis: a cross-sectional population-based study

Background Few population-based studies have assessed the prevalence and the risk factors of non-allergic rhinitis (NAR) in comparison to allergic rhinitis (AR). Moreover, epidemiologic data on rhinitis in the elderly subjects and in southern Europe are scarce. Objective This study aimed at estimating the prevalence and at comparing the risk factor distribution of AR and NAR in a...

The Course of Asthma in Young Adults: A Population-Based Nine-Year Follow-Up on Asthma Remission and Control

Background Only few longitudinal studies on the course of asthma among adults have been carried out. Objective The aim of the present prospective study, carried out between 2000 and 2009 in Italy, is to assess asthma remission and control in adults with asthma, as well as their determinants. Methods All the subjects with current asthma (21–47 years) identified in 2000 in the...

Socioeconomic inequalities in smoking habits are still increasing in Italy

Background Socioeconomic inequalities in smoking habits have stabilized in many Western countries. This study aimed at evaluating whether socioeconomic disparities in smoking habits are still enlarging in Italy and at comparing the impact of education and occupation. Methods In the frame of the GEIRD study (Gene Environment Interactions in Respiratory Diseases) 10,494 subjects...

Evolution of Asthma Severity in a Cohort of Young Adults: Is There Any Gender Difference?

Introduction Little is known about the distribution of asthma severity in men and women in the general population. The objective of our study was to describe asthma severity and change in severity according to gender in a cohort of adult asthmatics Methods Subjects with asthma were identified from random samples of the 22 to 44 year-olds from the general population, screened for...

Incidence of asthma and mortality in a cohort of young adults: a 7-year prospective study

Background Few longitudinal data exist on the incidence of asthma in young adults and on the overall mortality risk due to asthma. A 7-year follow-up prospective study was performed to assess the incidence of asthma and mortality from all causes in a cohort of young adults. Methods The life status of a cohort of 6031 subjects, aged 20–44 years, who replied to a respiratory...