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Search: authors:"Luz-Jeannette Sierra"

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Colonization of the cervicovaginal space with Gardnerella vaginalis leads to local inflammation and cervical remodeling in pregnant mice

. Soslowsky, Michal A. Elovitz. Formal analysis: Luz-Jeannette Sierra. Funding acquisition: Michal A. Elovitz. Investigation: Luz-Jeannette Sierra, Guillermo O. BarilaÂ, Carrie E. Barnum, Snehal S. Shetye ... . Methodology: Luz-Jeannette Sierra, Guillermo O. BarilaÂ. Project administration: Amy G. Brown. Supervision: Amy G. Brown, Louis J. Soslowsky, Michal A. Elovitz. 15 / 19 Writing ± original draft: Luz

A Role for microRNA-155 Modulation in the Anti-HIV-1 Effects of Toll-Like Receptor 3 Stimulation in Macrophages

HIV-1 infection of macrophages plays a key role in viral pathogenesis and progression to AIDS. Polyinosine-polycytidylic acid (poly(I∶C); a synthetic analog of dsRNA) and bacterial lipopolysaccharide (LPS), the ligands for Toll-like receptors (TLR) TLR3 and TLR4, respectively, are known to decrease HIV-1 infection in monocyte-derived macrophages (MDMs), but the mechanism(s) are...