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Search: authors:"Maarten R. Hillen"

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Circulating small non-coding RNAs reflect IFN status and B cell hyperactivity in patients with primary Sjögren’s syndrome

. Conceptualization: Ana P. Lopes, Maarten R. Hillen, Eleni Chouri, Aike A. Kruize, Joel A. G. van Roon, Timothy R. D. J. Radstake. Formal analysis: Ana P. Lopes, Maarten R. Hillen, Marzia Rossato, Joel A. G. van ... Roon. Investigation: Ana P. Lopes, Maarten R. Hillen, Eleni Chouri, Sofie L. M. Blokland, Cornelis Writing ± original draft: Ana P. Lopes, Maarten R. Hillen. Writing ± review & editing: Sofie L. M

The Additive Inflammatory In Vivo and In Vitro Effects of IL-7 and TSLP in Arthritis Underscore the Therapeutic Rationale for Dual Blockade

Introduction The cytokines interleukin (IL)-7 and thymic stromal lymphopoietin (TSLP) signal through the IL-7R subunit and play proinflammatory roles in experimental arthritis and rheumatoid arthritis (RA). We evaluated the effect of inhibition of IL-7R- and TSLPR-signalling as well as simultaneous inhibition of IL-7R- and TSLPR-signalling in murine experimental arthritis. In...