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26 papers found.
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Uncertainty-Wise Cyber-Physical System test modeling

It is important that a Cyber-Physical System (CPS) with uncertainty in its behavior caused by its unpredictable operating environment, to ensure its reliable operation. One method to ensure that the CPS will handle such uncertainty during its operation is by testing the CPS with model-based testing (MBT) techniques. However, existing MBT techniques do not explicitly capture...

The Reversal Effect and Its Mechanisms of Tetramethylpyrazine on Multidrug Resistance in Human Bladder Cancer

Laboratory of Urinary Cellular Molecular Diagnostics (Z151100001615060). Man Zhang received the funding. The funders had no role in study design, data collection and analysis, decision to publish, or ... bladder cancer Pumc-91/ADM cell line . Journal of Medical Research . 2009 ; 38 ( 1 ): 70 - 72 . 23. Zhao Man , Zhang Man , Ma Ping. Establishment of cisplatin-multidrug resistance cell line of human bladder

Genes associated with Alzheimer's disease: an overview and current status

Genes associated with Alzheimer's disease: an overview and current status Mohan Giri, Man Zhang, Yang Lü Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University

Evaluation of a liquid culture system in the detection of mycobacteria at an antituberculosis institution in China; A retrospective study

Objective A retrospective study comparing the diagnostic performance of the BACTEC™ MGIT™ 960 system (M960 system; BD Worldwide, Franklin Lakes, NJ, USA) with Löwenstein–Jensen (L–J) culture to detect mycobacteria in sputum specimens from patients with suspected pulmonary tuberculosis (TB).

Prevalence of chronic kidney disease markers: Evidence from a three-million married population with fertility desire in rural China

We aimed to assess the prevalence of chronic kidney diseases (CKD) markers among the married residents with fertility desire in rural China. Demographic and clinical data were collected from the National Free Pre-Conception Health Examination Project. Estimated glomerular filtration rate (eGFR) < 60 mL/min//1.73 m2, proteinuria, and hematuria were defined as markers of CKD. GFR...

Circulating C1q complement/TNF-related protein (CTRP) 1, CTRP9, CTRP12 and CTRP13 concentrations in Type 2 diabetes mellitus: In vivo regulation by glucose

Objectives The C1q complement/TNF-related protein (CTRP) superfamily, which includes the adipokine adiponectin, has been shown in animal models to have positive metabolic and cardiovascular effects. We sought to investigate circulating CTRP1, CTRP9, CTRP12 and CTRP13 concentrations in persons with type 2 diabetes mellitus (T2DM), with age and BMI matched controls, and to examine...

Two Urinary Peptides Associated Closely With Type 2 Diabetes Mellitus

Objective To monitor of type 2 diabetes more simply, conveniently and noninvasively, we are trying to identify the potential urinary peptides that associated with different stages of glucose control in type 2 diabetes mellitus. Methods Firstly, we collected urine samples from type 2 diabetic patients and normal controls. These type 2 diabetic patients were divided into two groups...

PPARgene: A Database of Experimentally Verified and Computationally Predicted PPAR Target Genes

The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of the nuclear receptor superfamily. Upon ligand binding, PPARs activate target gene transcription and regulate a variety of important physiological processes such as lipid metabolism, inflammation, and wound healing. Here, we describe the first database of PPAR target genes...

The Difference Quantity of Urinary Peptides between Two Groups of Type 2 Diabetic Patients with or without Coronary Artery Disease

Objectives. We aim to explore urinary biomarkers that could monitor CAD in type 2 diabetic patients. Materials and Methods. Urine samples from two groups, twenty-eight type 2 diabetic patients with coexisting CAD and thirty type 2 diabetic patients without CAD, were purified by MB-WCX and then analyzed by MALDI-TOF-MS. Subsequently, we compared the urinary peptide signatures of...

Efficiency Analysis of Wireless Power Transmission for Portable Electronics

With the portable electronics becoming more and more popular, a model of wireless power transmission for general portable electronics was presented based on the principles of magnetic resonance transmission. And that transferring the model to an equivalent circuit was possible to calculate. The characteristics of the system and the optimal conditions were analyzed, and the...

Melanophilin Stimulates Myosin-5a Motor Function by Allosterically Inhibiting the Interaction between the Head and Tail of Myosin-5a

Foundation of China (31171367) and the National Basic Research Program of China (2013CB932802 and 2012CB114102). Author information Author notesLin-Lin Yao, Qing-Juan Cao & Hai-Man Zhang These authors ... Sciences, Beijing 100101, ChinaLin-Lin Yao, Qing-Juan Cao, Hai-Man Zhang, Jie Zhang, Yang Cao & Xiang-dong LiUniversity of Chinese Academy of Sciences, Beijing 100049, ChinaQing-Juan Cao & Hai-Man Zhang

Comparison of the Antennal Sensilla Ultrastructure of Two Cryptic Species in Bemisia tabaci

Bemisia tabaci is an important agricultural pest with worldwide distribution and host preference. Therefore, understanding the biology of this pest is important to devise specific pest control strategies. The antennae of herbivorous insects play an important role in the identification of hosts using plant volatiles. To understand the features of antennae in B. tabaci MEAM 1...

Damage Characteristics of Coated Cylindrical Shells Subjected to Underwater Contact Explosion

It is of great significance for the protective design of submarine to study the influences of coverings on the damage characteristics of single and double cylindrical shells subjected to underwater contact explosions. The SPH models of single and double cylindrical shells coated with foam silicone rubber are established to analyze shockwave propagation, damage characteristics...

MiR-126 Suppresses the Glucose-Stimulated Proliferation via IRS-2 in INS-1 β Cells

Background Increasing evidence suggests that miR-126 participates in the glucose homeostasis through its target molecules. Although bioinformatics analysis predicts that miR-126 can bind with the insulin receptor substrate-2(IRS-2) mRNA at the “seed sequence”, but there are still no definitely reports to support it. In this study, we provided evidences that IRS-2 was one of the...

Identification and Characterization of a Novel Monoterpene Synthase from Soybean Restricted to Neryl Diphosphate Precursor

Terpenes are important defensive compounds against herbivores and pathogens. Here, we report the identification of a new monoterpene synthase gene, GmNES, from soybean. The transcription of GmNES was up-regulated in soybean plants that were infested with cotton leafworm (Prodenia litura), mechanically wounded or treated with salicylic acid (SA). Gas chromatography-mass...

Addition of Berberine to 5-Aminosalicylic Acid for Treatment of Dextran Sulfate Sodium-Induced Chronic Colitis in C57BL/6 Mice

Ulcerative colitis (UC) is a common chronic remitting disease but without satisfactory treatment. Alternative medicine berberine has received massive attention for its potential in UC treatment. Conventional therapies with the addition of berberine are becoming attractive as novel therapies in UC. In the present study, we investigated the preclinical activity of a conventional...

Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED

Polycomb repressive complex 2 (PRC2), a histone H3 lysine 27 methyltransferase, plays a key role in gene regulation and is a known epigenetics drug target for cancer therapy. The WD40 domain-containing protein EED is the regulatory subunit of PRC2. It binds to the tri-methylated lysine 27 of the histone H3 (H3K27me3), and through which stimulates the activity of PRC2...

Utility of gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage in premenopausal women with breast cancer: a systematic review and meta-analysis

,1 Xiao-Man Zhang,1 Meng Lv,1 Ling Chen,1 Tian-Jie Qin,1 Fan Wang,1 Jiao Yang,1 Pei-Jun Liu,2 Jin Yang1 1Department of Medical Oncology, 2Center for Translational Medicine, The First Affiliated

Isolation and Characterization of a Novel Endoglucanase from a Bursaphelenchus xylophilus Metagenomic Library

Interests: The authors have the following interests: co-authors Fengguang Du, Linfeng Wang and Man Zhang are employed by State Key Laboratory of Motor Bio-fuel technology, Henan Tianguan Group Co. Ltd