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8 papers found.
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Economic burden of community-acquired pneumonia among elderly patients: a Japanese perspective

Background This study aimed to estimate the economic burden of community-acquired pneumonia (CAP) among elderly patients in Japan. In addition, the study evaluated the relationship between total treatment cost and CAP risk factors. Methods An administrative database was searched for elderly patients (≥ 65 years old) who had pneumonia (ICD-10 code: J12–J18) and an antibiotic...

Polypharmacy and adverse drug reactions in Japanese elderly taking antihypertensives: a retrospective database study

decision to submit the manuscript for publication. Izumi Sato performed the statistical analyses and drafted the manuscript, and Manabu Akazawa collected the data and provided inputs into the of Japan for

Economic impact of switching to fixed-dose combination therapy for Japanese hypertensive patients: a retrospective cost analysis

Manabu Akazawa 0 Katsushi Fukuoka 1 0 Meiji Pharmaceutical University , Tokyo , Japan 1 Nihon Chouzai Co., Ltd. , Tokyo , Japan Background: The prescription of fixed-dose combinations (FDC) of

The 23-valent pneumococcal polysaccharide vaccine in patients with rheumatoid arthritis: a double-blinded, randomized, placebo-controlled trial

Background Pneumococcal pneumonia is the most frequent form of pneumonia. We herein assessed the effectiveness of the 23-valent pneumococcal polysaccharide vaccine (PPSV23) in the prevention of pneumonia overall in rheumatoid arthritis (RA) patients at risk for infections. We hypothesized that PPSV23 vaccination is superior in preventing pneumococcal pneumonia compared with...

Effect of abatacept on the immunogenicity of 23-valent pneumococcal polysaccharide vaccination (PPSV23) in rheumatoid arthritis patients

Introduction Patients with rheumatoid arthritis (RA) treated with abatacept (ABT) are at increased risk for vaccine-preventable infections. The aim of the present study is to evaluate the humoral response to 23-valent pneumococcal polysaccharide (PPSV23) vaccination in RA patients receiving ABT. Methods The immunogenicity study was nested within a randomized, double-blind placebo...

A cross-sectional investigation of the quality of selected medicines in Cambodia in 2010

Sovannarith Heng Bun Kiet Nam Nivanna Manabu Akazawa Hirohito Tsuboi 0 Tsuyoshi Tanimoto Kazuko Kimura 0 0 Drug Management and Policy, Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health

Pneumococcal polysaccharide vaccination in rheumatoid arthritis patients receiving tacrolimus

Introduction In rheumatoid arthritis (RA) patients receiving immunosuppressive treatments, vaccination against Streptococcus pneumoniae is recommended. The objective of the study was to evaluate the effects of tacrolimus (TAC) on immune response following administration of a 23-valent pneumococcal polysaccharide vaccine (PPSV23) in patients with established RA. Methods Patients...

Perceptions and practices of pharmaceutical wholesalers surrounding counterfeit medicines in a developing country: a baseline survey

Background Recent investigations by the Ministry of Health of Cambodia suggest that counterfeit medicines have been introduced into the pharmaceutical market in tampered packaging. To further explore this possibility, an interview survey was conducted at the wholesaler level to investigate the medicinal supply chain in Cambodia. Methods Managing executives of 62 (83.8...