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Search: authors:"Marcin Skrzypski"

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Prognostic value of 5-microRNA based signature in T2-T3N0 colon cancer

., 80-211 Gdan ́sk , Poland 1 Department of Surgical Oncology, Medical University of Gdansk , Gdansk , Poland 2 & Marcin Skrzypski 3 Department of Clinical Oncology, Centre of Oncology , Bydgoszcz ... expression; colon cancer metastasis; prognostic marker; miR-1300; miR-939 - Maciej Bobowicz and Marcin Skrzypski equally contributed to the presented study. Background Colon cancer (CC) is the fourth

The Role of TRAF4 and B3GAT1 Gene Expression in the Food Hypersensitivity and Insect Venom Allergy in Mastocytosis

Mastocytosis is an uncommon disease classified as a myeloproliferative neoplasm, however, its symptoms are broad and place patients at crossroads between dermatology, hematology and allergology. Patients with mastocytosis often suffer from symptoms resulting from the activation and release of mediators from the mast cells, such as generalized itching, redness, headache, abdominal ...

Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations

Background The development of a more refined prognostic methodology for early non-small cell lung cancer (NSCLC) is an unmet clinical need. An accurate prognostic tool might help to select patients at early stages for adjuvant therapies. Results A new integrated bioinformatics searching strategy, that combines gene copy number alterations and expression, together with clinical ...

BRCA1: A Novel Prognostic Factor in Resected Non-Small-Cell Lung Cancer

BackgroundAlthough early-stage non-small-cell lung cancer (NSCLC) is considered a potentially curable disease following complete resection, patients have a wide spectrum of survival according to stage (IB, II, IIIA). Within each stage, gene expression profiles can identify patients with a higher risk of recurrence. We hypothesized that altered mRNA expression in nine genes could ...