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Bacteremic Pneumonia Due to Staphylococcus aureus: A Comparison of Disease Caused by Methicillin-Resistant and Methicillin-Susceptible Organisms

We performed a prospective study of all patients with bacteremic pneumonia due to Staphylococcus aureus over a period of 6 years during an outbreak of methicillin-resistant S. aureus (MRSA). Patients with bacteremic pneumonia due to MRSA (32 cases) or methicillin-susceptible S. aureus (MSSA; 54 cases) were compared. The patients with MRSA pneumonia were older and were more likely ...

Nosocomial Outbreak of Burkholderia pickettii Infection Due to a Manufactured Intravenous Product Used in Three Hospitals

Forty-six cases of nosocomial infection caused by Burkholderia pickettii were reported between June and November 1993 in three metropolitan hospitals in Madrid. A case-control study of the outbreak was conducted to identify its cause. Seventy-four percent of the patients were males; the mean age ± SD of the patients was 54 ± 20 years. Sixty-five percent of the patients presented ...

Evaluation of participatory teaching methods in undergraduate medical students’ learning along the first academic courses

Miguel Biscaia for their support Author Contributions Conceptualization: Beatriz Gal. Data curation: Eva Iglesias, PurificacioÂn GonzaÂlez. Formal analysis: Margarita Rubio. Funding acquisition ... : Beatriz Gal. Investigation: Beatriz Gal. Methodology: Beatriz Gal, Margarita Rubio, PurificacioÂn GonzaÂlez. Project administration: Beatriz Gal. Supervision: Beatriz Gal. Validation: Beatriz Gal

Relationship between Genotypes Sult1a2 and Cyp2d6 and Tamoxifen Metabolism in Breast Cancer Patients

Tamoxifen is a pro-drug widely used in breast cancer patients to prevent tumor recurrence. Prior work has revealed a role of cytochrome and sulfotransferase enzymes in tamoxifen metabolism. In this descriptive study, correlations were examined between concentrations of tamoxifen metabolites and genotypes for CYP2D6, CYP3A4, CYP3A5, SULT1A1, SULT1A2 and SULT1E1 in 135 patients with ...