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Training improves the handling of inhaler devices and reduces the severity of symptoms in geriatric patients suffering from chronic-obstructive pulmonary disease

-Christine Luley, Tobias Loleit, Elmar Knopf, Marija Djukic & Roland Nau Institute of Neuropathology, University Medical Center Göttingen, Göttingen, Germany Marie-Christine Luley, Marija Djukic & Roland Nau ... PubMed Google Scholar Marija Djukic View author publications You can also search for this author in PubMed Google Scholar Carl-Peter Criée View author publications You can also search for this

Cerebrospinal fluid abnormalities in meningeosis neoplastica: a retrospective 12-year analysis

Meningeosis neoplastica is a diffuse metastatic spread of tumor cells in the subarachnoid space. Although first recognized in 1870, systematic investigations regarding cerebrospinal fluid (CSF) constituents in this condition are scarce. Routine CSF samples analyzed from 2001 to 2012 at the Laboratory of Clinical Neurochemistry, University of Göttingen, were re-evaluated. Patients...

Small cisterno-lumbar gradient of phosphorylated Tau protein in geriatric patients with suspected normal pressure hydrocephalus

Background The composition of the cerebrospinal fluid (CSF) is not homogeneous, and concentrations of proteins from different origins diverge among ventricular, cisternal and lumbar CSF fractions. Concentrations of blood-derived proteins increase and of brain-derived proteins decrease from ventricular to lumbar fractions. We studied whether the origin of the CSF portion analysed...

Small cisterno-lumbar gradient of phosphorylated Tau protein in geriatric patients with suspected normal pressure hydrocephalus

suitable for the assessment of markers of dementia in CSF. Notes Marija Djukic and Annette Spreer contributed equally to this work Abbreviations Tau:  Tau protein pTau:  phosphorylated Tau protein

Unilateral phrenic nerve lesion in Lyme neuroborreliosis

Background Among a variety of more common differential diagnoses, the aetiology of acute respiratory failure includes Lyme neuroborreliosis. Case presentation We report an 87-years old huntsman with unilateral phrenic nerve palsy as a consequence of Lyme neuroborreliosis. Conclusion Although Lyme neuroborreliosis is a rare cause of diaphragmatic weakness, it should be considered...

Unilateral phrenic nerve lesion in Lyme neuroborreliosis

Among a variety of more common differential diagnoses, the aetiology of acute respiratory failure includes Lyme neuroborreliosis. We report an 87-years old huntsman with unilateral phrenic nerve palsy as a consequence of Lyme neuroborreliosis. Although Lyme neuroborreliosis is a rare cause of diaphragmatic weakness, it should be considered in the differential workup because of...

Neurocognitive functions and brain atrophy after proven neuroborreliosis: a case-control study

battery. Marija Djukic, Roland Nau and Manfred Holzgraefe contributed to the recruitment and neurological examination of patients and the control persons. Peter Dechent was responsible for the MRI

Neurocognitive functions and brain atrophy after proven neuroborreliosis: a case-control study

no competing interests. Authors’ contributions Carsten Schmidt-Samoa performed the neuropsychological assessment and was involved in the assembly of the test battery. Marija Djukic, Roland Nau and

Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice

Background Meningoencephalitis caused by Escherichia coli is associated with high rates of mortality and risk of neurological sequelae in newborns and infants and in older or immunocompromised adults. A high prevalence of neurological disorders has been observed in geriatric populations at risk of hypovitaminosis D. Methods In vivo, we studied the effects of vitamin D3 on...

Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice

Meningoencephalitis caused by Escherichia coli is associated with high rates of mortality and risk of neurological sequelae in newborns and infants and in older or immunocompromised adults. A high prevalence of neurological disorders has been observed in geriatric populations at risk of hypovitaminosis D. In vivo, we studied the effects of vitamin D3 on survival and the host’s...

Cerebrospinal fluid findings in adults with acute Lyme neuroborreliosis

Presence of BB-specific antibodies in the cerebrospinal fluid (CSF) with evidence of their intrathecal production in conjunction with the white cell count in the CSF and typical clinical symptoms is the traditional diagnostic gold standard of Lyme neuroborreliosis (LNB). Few data are available on the CSF lactate concentration in European adults with the diagnosis of acute LNB...

Cognition after malignant media infarction and decompressive hemicraniectomy - a retrospective observational study

Background Decompressive hemicraniectomy is a life-saving procedure for patients with malignant middle cerebral artery infarctions. However, the neuropsychological sequelae in such patients have up to now received little attention. In this study we not only describe neuropsychological deficits but also the quality of life and the extent of depression and other psychiatric...

Cognition after malignant media infarction and decompressive hemicraniectomy - a retrospective observational study

Decompressive hemicraniectomy is a life-saving procedure for patients with malignant middle cerebral artery infarctions. However, the neuropsychological sequelae in such patients have up to now received little attention. In this study we not only describe neuropsychological deficits but also the quality of life and the extent of depression and other psychiatric symptoms in...