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Search: authors:"Marsilius Mues"

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Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy

Center for help with the preclinical trial. Author Contributions Conceptualization: Olga Ksionda, Jeroen P. Roose. gen, Jesse Jun, Ksenia Matlawska-Wasowska. Data curation: Olga Ksionda, Marsilius Mues ... , Anica M. Wandler, Lisa Donker, Milou TenhaFormal analysis: Olga Ksionda, Marsilius Mues, Anica M. Wandler, Lisa Donker, Milou Tenhagen, Jesse Jun, Ksenia Matlawska-Wasowska. Funding acquisition: Kevin

Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

Background There is consensus that experimental autoimmune encephalomyelitis (EAE) can be mediated by myelin specific T cells of Th1 as well as of Th17 phenotype, but the contribution of either subset to the pathogenic process has remained controversial. In this report, we compare functional differences and pathogenic potential of “monoclonal” T cell lines that recognize myelin...