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Sudden unexplained death in alcohol misuse (SUDAM) patients have different characteristics to those who died from sudden arrhythmic death syndrome (SADS)

, London SW17 0QT , UK 2 Mary N. Sheppard There is growing awareness of sudden unexplained death in alcohol misuse (SUDAM) in which there is no obvious cause of death, no evidence of acute alcohol toxicity

Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology

Although sudden cardiac death (SCD) is one of the most important modes of death in Western countries, pathologists and public health physicians have not given this problem the attention it deserves. New methods of preventing potentially fatal arrhythmias have been developed and the accurate diagnosis of the causes of SCD is now of particular importance. Pathologists are...

Constrictive Pericarditis and Rheumatoid Nodules with Severe Aortic Incompetence

The case of a female patient presenting with constrictive rheumatoid pericarditis and aortic incompetence secondary to valvular rheumatoid nodules is described along with a review of the literature with the aim to highlight this rare cause of aortic insufficiency.

Unusual presentation of primary cardiac lymphoma☆

Cardiac lymphomas are rare neoplasms and account for a minor proportion of primary cardiac malignancies. Secondary involvement of the heart and pericardium by systemic lymphoma is well documented, but primary lymphomas of heart and pericardium are extremely rare, accounting for ∼2% of all primary cardiac tumours. Most cases are diagnosed at autopsy, but nowadays, with modern...

Calibration of myocardial T2 and T1 against iron concentration

Background The assessment of myocardial iron using T2* cardiovascular magnetic resonance (CMR) has been validated and calibrated, and is in clinical use. However, there is very limited data assessing the relaxation parameters T1 and T2 for measurement of human myocardial iron. Methods Twelve hearts were examined from transfusion-dependent patients: 11 with end-stage heart failure...

Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome

Background To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer. Case presentation Cycle monitoring in IVF identified an abnormal ovarian lesion which was subjected to ultrasound-guided needle...

Ultra-short echo time cardiovascular magnetic resonance of atherosclerotic carotid plaque

Background Multi-contrast weighted cardiovascular magnetic resonance (CMR) allows detailed plaque characterisation and assessment of plaque vulnerability. The aim of this preliminary study was to show the potential of Ultra-short Echo Time (UTE) subtraction MR in detecting calcification. Methods 14 ex-vivo human carotid arteries were scanned using CMR and CT, prior to...

p53, cellular proliferation, and apoptosis-related factors in thymic neuroendocrine tumors

Lung Hospital, London, UKMary N Sheppard AuthorsSearch for Anthony A Gal in:Nature Research journals • PubMed • Google ScholarSearch for Mary N Sheppard in:Nature Research journals • PubMed • Google