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Timing of tracheotomy in ICU patients: a systematic review of randomized controlled trials

Introduction The optimal timing of tracheotomy in critically ill patients remains a topic of debate. We performed a systematic review to clarify the potential benefits of early versus late tracheotomy. Methods We searched PubMed and CENTRAL for randomized controlled trials that compared outcomes in patients managed with early and late tracheotomy. A random-effects meta-analysis, ...

Complete bronchial obstruction by granuloma in a paediatric patient with translaryngeal endotracheal tube: a case report

Onodera Hideaki Imanaka Masaji Nishimura Introduction: Although continuous or frequent stimuli in tracheostomized patients may cause tracheal granulomas, little is known about management of patients with

Successful use of extracorporeal membrane oxygenation in the reversal of cardiorespiratory failure induced by atonic uterine bleeding: a case report

Introduction Although extracorporeal membrane oxygenation has made sufficient progress to be considered for the management of life-threatening cardiac and respiratory failure, the risk of hemorrhagic complications may outweigh the benefits for patients with bleeding tendencies. We report, to the best of our knowledge, the first case of successful treatment by extracorporeal ...

Blood Lactate/ATP Ratio, as an Alarm Index and Real-Time Biomarker in Critical Illness

Objective The acute physiology, age and chronic health evaluation (APACHE) II score and other related scores have been used for evaluation of illness severity in the intensive care unit (ICU), but there is still a need for real-time and sensitive prognostic biomarkers. Recently, alarmins from damaged tissues have been reported as alarm-signaling molecules. Although ATP is a member ...

Effect of heat and moisture exchanger (HME) positioning on inspiratory gas humidification

Background In mechanically ventilated patients, we investigated how positioning the heat and moisture exchanger (HME) at different places on the ventilator circuit affected inspiratory gas humidification. Methods Absolute humidity (AH) and temperature (TEMP) at the proximal end of endotracheal tube (ETT) were measured in ten mechanically ventilated patients. The HME was connected ...

Chest computed tomography of a patient revealing severe hypoxia due to amniotic fluid embolism: a case report

Introduction Amniotic fluid embolism is one of the most severe complications in the peripartum period. Because its onset is abrupt and fulminant, it is unlikely that there will be time to examine the condition using thoracic computed tomography (CT). We report a case of life-threatening amniotic fluid embolism, where chest CT in the acute phase was obtained. Case presentation A ...

Hyperbilirubinaemia after major thoracic surgery: comparison between open-heart surgery and oesophagectomy

Background Hyperbilirubinaemia is a common occurrence in patients who are admitted to intensive care units (ICUs) after major surgery, and it is associated with high mortality. We investigated the incidence of hyperbilirubinaemia after two major types of thoracic surgery: open-heart surgery and oesophagectomy. In order to identify the risk factors associated with ...

Extracorporeal membrane oxygenation for 2009 influenza A(H1N1) severe respiratory failure in Japan

Purpose To evaluate procedures and outcomes of extracorporeal membrane oxygenation (ECMO) therapy applied to 2009 influenza A(H1N1) severe respiratory failure patients in Japan. Methods This observational study used database information about adults who received ECMO therapy for H1N1-related severe respiratory failure from April 1, 2010 to March 31, 2011. Results Fourteen patients ...

Effects of reduced rebreathing time, in spontaneously breathing patients, on respiratory effort and accuracy in cardiac output measurement when using a partial carbon dioxide rebreathing technique: a prospective observational study

Introduction New technology using partial carbon dioxide rebreathing has been developed to measure cardiac output. Because rebreathing increases respiratory effort, we investigated whether a newly developed system with 35 s rebreathing causes a lesser increase in respiratory effort under partial ventilatory support than does the conventional system with 50 s rebreathing. We also ...

Correction: Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study

5 11 12 Koji Hoshino 6 11 12 Koji Hosokawa 3 11 12 Kook Hyun Lee 4 11 12 Kyoung Min Lee 1 11 12 Makoto Takatori 11 12 23 Masaji Nishimura 11 12 20 Masamitsu Sanui 2 11 12 Masanori Ito 11 12 27

Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study

Kenji Uehara Kentaro Dote Kimitaka Tajimi Kiyoshi Morita 0 Koichi Matsuo Koji Hoshino Koji Hosokawa Kook Hyun Lee Kyoung Min Lee Makoto Takatori Masaji Nishimura Masamitsu Sanui Masanori Ito Moritoki Egi ... Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea). Japan: Masaji Nishimura, M.D. PhD (Department of Emergency and Critical Care Medicine

Does the tube-compensation function of two modern mechanical ventilators provide effective work of breathing relief?

Objective An endotracheal tube (ETT) imposes work of breathing on mechanically ventilated patients. Using a bellows-in-a-box model lung, we compared the tube compensation (TC) performances of the Nellcor Puritan-Bennett 840 ventilator and of the Dräger Evita 4 ventilator. Measurements and results Each ventilator was connected to the model lung. The respiratory rate of the model ...

Respiratory outcome in extremely premature infants following ketamine anaesthesia

, Hiroshi Ueyama MD, Masaji Nishimura MDPhD, Norihumi Oka MD Premature infants are prone to develop postoperative apnoea. The purpose of the present study was to determine if riskfactors could be identified