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Search: authors:"Masamichi Imai"

9 papers found.
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Assessment of safety, efficacy, and dosimetry of a novel 18-kDa translocator protein ligand, [11C]CB184, in healthy human volunteers

Background N,N-di-n-propyl-2-[2-(4-[11C]methoxyphenyl)-6,8-dichloroimidazol[1,2-a]pyridine-3-yl]acetamide ([11C]CB184) is a novel selective radioligand for the 18-kD translocator protein (TSPO), which is upregulated in activated microglia in the brain, and may be useful in positron emission tomography (PET). We examined the safety, radiation dosimetry, and initial brain imaging...

Allergin-1 inhibits TLR2-mediated mast cell activation and suppresses dermatitis

TLR2 recognizes cell wall components of Staphylococcus aureus, which colonizes >90% of atopic eczematous skin lesions. The regulatory mechanisms of TLR2 signaling in the skin remain unclear. Allergin-1, an inhibitory immunoglobulin-like receptor containing an ITIM, is expressed on mast cells (MCs) and inhibits IgE-mediated anaphylaxis in mice. Here, we show that Allergin-1...

Multi-ethnic evaluation of fully automatic planning assist system for cardiac magnetic resonance imaging

Shigehide Kuhara Shuhei Nitta Taichiro Shiodera Yukinobu Sakata Tomoyuki Takeguchi Kenichi Yokoyama Reiko Ishimura Toshiya Kariyasu Masamichi Imai Toshiaki Nitatori Timothy Albert - From 17th

Expression and Function of Allergin-1 on Human Primary Mast Cells

MC exhibits similar characteristics as mouse Allergin-1 in the expression profile and function. - Competing Interests: Masamichi Imai and Shiro Shibayama are employees of Ono Pharmaceutical Company

Effects of quality of dictionary in knowledge-based 6-plane automatic slice-alignment method for cardiac magnetic resonance imaging

Shigehide Kuhara Shuhei Nitta Tomoyuki Takeguchi Nobuyuki Matsumoto Kenichi Yokoyama Masamichi Imai Rieko Ishimura Toshiaki Nitatori From th Annual SCMR Scientific Sessions Orlando FL USA. February