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Aortic aneurysm rupture as a rare complication of granulomatosis with polyangiitis: a case report

Kazuya Kurakami 0 Masaru Aoyagi 0 Seiji Kakehata 0 0 Department of Otolaryngology, Yamagata University Faculty of Medicine , 2-2-2 Iida-nishi, Yamagata 990-23 , Japan Introduction: Granulomatosis with

A Case of Sublingual Dermoid Cyst: Extending the Limits of the Oral Approach

Aoyagi Department of Otolaryngology, Head and Neck Surgery, Yamagata University Faculty of Medicine, 2-2-2 Iida-nishi, Yamagata 990-9585, Japan Received 17 May 2012; Accepted 3 September 2012 Academic

Clinical and Pathological Characteristics of Organized Hematoma

Objective. To study the clinical and pathological characteristics of patients with organized hematoma with malignant features in maxillary sinuses. Subjects and Methods. This was a retrospective study of five patients who were treated surgically for organized hematoma. The preoperative CT and MRI findings were studied clinically. The expressions of CD31, CD34, and periostin in...

Contributions of biological tumor parameters to the incorporation rate of l-[methyl-11C] methionine into astrocytomas and oligodendrogliomas

We compared the tumor uptake of 11C-methionine (MET) with positron emission tomography (PET) with the results of a pathological analysis to examine the proliferative potential and microvessel density measured with immunostaining for MIB-1 and factor VIII, respectively, from 33 patients with glioma. The MET uptake in oligodendrogliomas was significantly greater than that in grade...

Stem Cells

highly adaptive glioma stem-like cell population. SC-21. EXPANSION OF CD133-POSITIVE GLIOMA CELLS IN RECURRENT DE NOVO GLIOBLASTOMAS AFTER RADIATION AND CHEMOTHERAPY Kaoru Tamura 1, Masaru Aoyagi 1 ... therapeutic reagent targeting CSCs in GBM. SC-33. CLINICAL RELEVANCE OF CD133-POSITIVE COLON CANCER STEM CELLS TO BRAIN METASTASIS FORMATION Masaru Aoyagi 1, Yoshiyuki Matsuoka 1, Kaoru Tamura 1, Noboru Ando 2


Treatment of GBM with anti-angiogenic agents (AA) is changing the paradigm of patterns of recurrence, with tumor often recurring in a non-enhancing, diffusely invasive phenotype. Despite this, delineation of voxels at risk for progression for radiotherapy (RT) is purely a geometric expansion of anatomic (T1,T2) MRI. We hypothesize that by integrating spectroscopic, diffusion- and...


In vivo MR spectroscopy (MRS) provides information about metabolite concentrations in tissue. Recently, citrate (Cit) was detected by MRS in subgroups of pediatric brain tumors. Citrate is an intermediate in the tricarboxylic acid (TCA) cycle and accumulates in tissue when the glycolytic rate exceeds the TCA cycle activity, a feature of malignant tumors. Currently, no practical...