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3 papers found.
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ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics

/ 22 Author Contributions Conceptualization: Jamie S. Lin, Jin Seok Jeon, Lawrence B. Holzman. Data curation: Jamie S. Lin, Jin Seok Jeon, Qingfeng Fan, Hetty N. Wong, Matthew B. Palmer, Lawrence B ... . Lin, Jin Seok Jeon, Qingfeng Fan, Hetty N. Wong, Matthew B. Palmer, Lawrence B. Holzman. Methodology: Jamie S. Lin, Jin Seok Jeon, Qingfeng Fan, Hetty N. Wong, Lawrence B. Holzman. Project

Comparison of amyloid deposition in human kidney biopsies as predictor of poor patient outcome

Background Amyloidosis leads to deposition of abnormal protein with beta-pleated sheet structure in specific compartments of the affected organs. The histological localization of these amyloid deposits determines the overall survival of the patient. Methods In this study we have assessed the histological localization and severity of amyloid deposition in 35 patients with ...

Intensity modulated radiation therapy (IMRT): differences in target volumes and improvement in clinically relevant doses to small bowel in rectal carcinoma

Background A strong dose-volume relationship exists between the amount of small bowel receiving low- to intermediate-doses of radiation and the rates of acute, severe gastrointestinal toxicity, principally diarrhea. There is considerable interest in the application of highly conformal treatment approaches, such as intensity-modulated radiation therapy (IMRT), to reduce dose to ...