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Hi-C analysis: from data generation to integration

visualizing such large genomics datasets. KeywordsChromatin 3D architecture Epigenomics Computational biology High-throughput sequencing Chromosome conformation capture  Mattia Forcato and Francesco Ferrari ... declares that he has no conflict of interest. Mattia Forcato declares that he has no conflict of interest. Francesco Ferrari declares that he has no conflict of interest. Ethical approval This article does

Glucocorticoid receptor signalling activates YAP in breast cancer

journals • PubMed • Google ScholarSearch for Elisa Cappuzzello in:Nature Research journals • PubMed • Google ScholarSearch for Mattia Forcato in:Nature Research journals • PubMed • Google ScholarSearch for

Dynamic Effects of Topoisomerase I Inhibition on R-Loops and Short Transcripts at Active Promoters

Topoisomerase I-DNA-cleavage complexes (Top1cc) stabilized by camptothecin (CPT) have specific effects at transcriptional levels. We recently reported that Top1cc increase antisense transcript (aRNAs) levels at divergent CpG-island promoters and, transiently, DNA/RNA hybrids (R-loop) in nuclear and mitochondrial genomes of colon cancer HCT116 cells. However, the relationship...

Hmgb3 Is Regulated by MicroRNA-206 during Muscle Regeneration

Background MicroRNAs (miRNAs) have been recently involved in most of human diseases as targets for potential strategies to rescue the pathological phenotype. Since the skeletal muscle is a spread-wide highly differentiated and organized tissue, rescue of severely compromised muscle still remains distant from nowadays. For this reason, we aimed to identify a subset of miRNAs major...