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Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels

-rectifying potassium channel 6; NBD, nucleotide binding domain; SUR, sulfonylurea receptor; TMD0-L0, transmembrane domain 0-loop 0 COMPLIANCE WITH ETHICS GUIDELINES Jing-Xiang Wu, Dian Ding, Mengmeng Wang ... CONTRIBUTIONS Lei Chen initiated the project. Jiang-Xiang Wu, Dian Ding, Mengmeng Wang, Yunlu Kang, Xin Zeng and Lei Chen designed experiments. Jiang-Xiang Wu prepared the cryo-EM sample. Jiang-Xiang Wu

Automated tracking and quantification of angiogenic vessel formation in 3D microfluidic devices

coordinates (migration velocities). Branching and anastomosis may also be predicted, since these are processes often accompanied with cell phenotypic changes. Conceptualization: Mengmeng Wang, Lee-Ling Sharon ... Ong, Justin Dauwels, H. Harry Asada. 26 / 30 Data curation: Mengmeng Wang, Lee-Ling Sharon Ong. Formal analysis: Mengmeng Wang. Funding acquisition: Justin Dauwels, H. Harry Asada. Investigation

Study of retina and choroid biological parameters of rhesus monkeys eyes on scleral collagen cross-linking by riboflavin and ultraviolet A

measurement and analysis of the IOP and OCT images used in this study. Methodology: Mingshen Sun, Bowen Ouyang, Mengmeng Wang, Yu Li, Xuan Jiao, Li Zhang. Project administration: Mingshen Sun, Fengju Zhang

Study on Mechanical Features of Brazilian Splitting Fatigue Tests of Salt Rock

The microtest, SEM, was carried out to study the fracture surface of salt rock after the Brazilian splitting test and splitting fatigue test were carried out with a servo-controlled test machine RMT-150B. The results indicate that the deviation of using the tablet splitting method is larger than that of using steel wire splitting method, in Brazilian splitting test of salt rock...

Embeddable Advanced Sensors for Harsh Environment Sensing Applications

contribution to this special issue. We hope all the readers can enjoy the papers in the special issue as we do. Lei Yuan Yinan Zhang Yan Lu Xiaobei Zhang Mengmeng Wang

Allelopathic effect boosts Chrysosporum ovalisporum dominance in summer at the expense of Microcystis panniformis in a shallow coastal water body

The increased occurrence of harmful cyanobacterial species and, with this, higher frequency of cyanobacteria blooms, closely associated with eutrophication and climate change, have attracted increasing attention worldwide. However, competition mechanisms between the different bloom-forming cyanobacteria species remain to be elucidated. In this paper, for the first time, the...

Effect of Glyceraldehyde Cross-Linking on a Rabbit Bullous Keratopathy Model

Ophthalmology, Xingtai, Hebei 054001, China Received 31 May 2015; Revised 14 July 2015; Accepted 26 July 2015 Academic Editor: Vito Romano Copyright © 2015 Mengmeng Wang. This is an open access article

Effect of Glyceraldehyde Cross-Linking on a Rabbit Bullous Keratopathy Model

Ophthalmology, Xingtai, Hebei 054001, China Received 31 May 2015; Revised 14 July 2015; Accepted 26 July 2015 Academic Editor: Vito Romano Copyright © 2015 Mengmeng Wang. This is an open access article

Effects of scleral cross-linking using genipin on the process of form-deprivation myopia in the guinea pig: a randomized controlled experimental study

Background Scleral cross-linking (CXL) is a novel attempt to slow down the axial elongation process in animal eyes. As a natural CXL reagent, genipin would be also effective for the prevention of myopia process. Thus, the present study was designed to evaluate the effects of scleral cross-linking using genipin on the form-deprivation (FD) myopia process of guinea pigs. Methods...

A Multilayer Naïve Bayes Model for Analyzing User’s Retweeting Sentiment Tendency

130012, China Received 28 May 2015; Accepted 17 August 2015 Academic Editor: Stefan Haufe Copyright © 2015 Mengmeng Wang et al. This is an open access article distributed under the Creative Commons

A Novel Adaptive Conditional Probability-Based Predicting Model for User’s Personality Traits

, Changchun 130012, China Received 13 March 2015; Accepted 21 June 2015 Academic Editor: Antonino Laudani Copyright © 2015 Mengmeng Wang et al. This is an open access article distributed under the Creative

Pathogenic variants screening in seventeen candidate genes on 2p15 for association with ankylosing spondylitis in a Han Chinese population

Objectives Previous studies have found the association between rs10865331 in 2p15 area and ankylosing spondylitis (AS). This study aimed to identify additional functional genetic variants in 2p15 region associated with AS susceptibility. Methods We used next generation sequencing (NGS) in 100 AS cases and 100 healthy controls to screen AS susceptible genetic variants, and...

A Multidimensional Nonnegative Matrix Factorization Model for Retweeting Behavior Prediction

University, Changchun 130012, China Received 22 October 2014; Accepted 6 February 2015 Academic Editor: Sergio Preidikman Copyright © 2015 Mengmeng Wang et al. This is an open access article distributed

The Clinical Value of Oxymatrine in Preventing Lamivudine Induced YMDD Mutation: A Meta-Analysis

(Mengmeng Wang and Wenwen Chen) independently assessed the risk of bias for each included randomised trial. Disagreements were resolved by discussion with Jian Jiang and Weian Yuan. We assessed the following

An efficient source of frequency anti-correlated entanglement at telecom wavelength

We demonstrate an efficient generation of frequency anti-correlated entangled photon pairs at telecom wavelength. The fundamental laser is a continuous-wave high-power fiber laser at 1560 nm, through an extracavity frequency doubling system, a 780-nm pump with a power as high as 742 mW is realized. After single-passing through a periodically poled KTiOPO4 (PPKTP) crystal...

Time-dependent toxicity of cadmium telluride quantum dots on liver and kidneys in mice: histopathological changes with elevated free cadmium ions and hydroxyl radicals

Time-dependent toxicity of cadmium telluride quantum dots on liver and kidneys in mice: histopathological changes with elevated free cadmium ions and hydroxyl radicals Mengmeng Wang,1,2,* Jilong Wang

Analysis on the situation of subjective well-being and its influencing factors in patients with ankylosing spondylitis

Background To examine the subjective well-being (SWB) in patients with ankylosing spondylitis (AS) compared with the healthy controls, and to explore the associations between SWB and demographic characteristics, disease-specific variables in AS patients. Methods SWB was assessed with General Well-Being Schedule (GWBS) in 200 AS patients and 210 healthy controls. Comparisons among...

Combination Therapy of Sorafenib and TACE for Unresectable HCC: A Systematic Review and Meta-Analysis

Background and Aim A large number of studies have tried to combine sorafenib with TACE for patients with unresectable hepatocellular carcinoma (HCC) and the results were controversial. We conducted this systematic review and meta-analysis to evaluate the safety and efficacy of combination therapy of sorafenib and TACE in the management of unresectable HCC. Methods MEDLINE...

Brassinosteroids play a critical role in the regulation of pesticide metabolism in crop plants

. ChinaYanhong Zhou, Xiaojian Xia, Gaobo Yu, Jitao Wang, Jingxue Wu, Mengmeng Wang, Youxin Yang, Kai Shi & Jingquan YuInstitute of Pesticide & Environmental Toxicology, Zijingang Campus, Zhejiang University, 866 ... journals • PubMed • Google ScholarSearch for Mengmeng Wang in:Nature Research journals • PubMed • Google ScholarSearch for Youxin Yang in:Nature Research journals • PubMed • Google ScholarSearch for Kai Shi

Secretome diversity and quantitative analysis of cellulolytic Aspergillus fumigatus Z5 in the presence of different carbon sources

Background Aspergillus fumigatus Z5 has a strong ability to decompose lignocellulose biomass, and its extracellular protein secretion has been reported in earlier studies employing traditional techniques. However, a comprehensive analysis of its secretion in the presence of different carbon sources is still lacking. The goal of this work was to identify, quantify and compare the...