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39 papers found.
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Measuring the microbiome of chronic wounds with use of a topical antimicrobial dressing – A feasibility study

, Mi Zhou. Formal analysis: Lindsay Kalan, Mi Zhou. Funding acquisition: Lindsay Kalan, Benjamin Willing. Investigation: Lindsay Kalan, Michele Labbie. Methodology: Lindsay Kalan, Mi Zhou, Michele ... Labbie, Benjamin Willing. Project administration: Michele Labbie, Benjamin Willing. 16 / 19 Resources: Benjamin Willing. Supervision: Benjamin Willing. Writing ± original draft: Lindsay Kalan, Mi Zhou

The Foreign Labor Increase Impact on the Wages of Local Residents: From the Perspective of City Scale

we used CGSS2008 data and found that the influence was not significant for the local residents on migrant labors flowing, while the migrant workers increased by 1%, the annual wage income of residents in provincial city increase 1.46%, but fell 0.83% in small and medium-sized city. Therefore, the relationship between migrants and local residents is complementary effect and...

miR-199a-5p suppresses human bladder cancer cell metastasis by targeting CCR7

Background C-C chemokine receptor type 7 (CCR7) overexpression correlated with lymphatic metastasis and poor prognosis is a major obstacle to bladder cancer treatment. Recent studies have revealed that miR-199a-5p was significantly abnormal expressed in several solid tumors and functioned as oncogene or tumor suppressor. This study was aimed to further investigate the effects of...

The effects of urbanization on the environment pollution in China (2002-2012)

This paper provides an analytical framework to evaluate whether urbanization could lead to environment pollution or not. This study uses STIRPAT model and recently developed panel regression techniques that allow for heterogeneous slope coefficients and cross-section dependence to model the impact that urbanization has on SO2 emissions for a panel of 28 provinces in China from...

Enhanced Detection of Low-Abundance Human Plasma Proteins by Integrating Polyethylene Glycol Fractionation and Immunoaffinity Depletion

The enormous depth complexity of the human plasma proteome poses a significant challenge for current mass spectrometry-based proteomic technologies in terms of detecting low-level proteins in plasma, which is essential for successful biomarker discovery efforts. Typically, a single-step analytical approach cannot reduce this intrinsic complexity. Current simplex immunodepletion...

Mid-term results of coronary bypass graft surgery in patients with ischaemic left ventricular systolic dysfunction and no detected myocardial viability

OBJECTIVES There are concerns about effects of surgical revascularization on patients with ischaemic systolic dysfunction when no signs of myocardial viability have been detected by nuclear imaging preoperatively. We reviewed our data to determine the efficacy of coronary bypass graft in this special patient cohort.

Phytoestrogens and risk of prostate cancer: a meta-analysis of observational studies

Background Epidemiologic studies have reported various results relating phytoestrogens to prostate cancer (PCa). The aim of this study was to provide a comprehensive meta-analysis on the extent of the possible association between phytoestrogens (including consumption and serum concentration) and the risk of PCa. Methods Eligible studies were retrieved via both computer searches...

tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily

TrmJ proteins from the SPOUT methyltransferase superfamily are tRNA Xm32 modification enzymes that occur in bacteria and archaea. Unlike archaeal TrmJ, bacterial TrmJ require full-length tRNA molecules as substrates. It remains unknown how bacterial TrmJs recognize substrate tRNAs and specifically catalyze a 2′-O modification at ribose 32. Herein, we demonstrate that all six...

Suppression of thrust fluctuation of doubly-fed linear motor

Ying WANG 0 Kunlun ZHANG 0 Mi ZHOU 0 0 Key Laboratory of Magnetic Levitation Technologies and Maglev Trains (Ministry of Education of China), School of Electrical En- gineering, Southwest Jiaotong

CCL21/CCR7 Enhances the Proliferation, Migration, and Invasion of Human Bladder Cancer T24 Cells

Objective To investigate the effects of CCL21/CCR7 on the proliferation, migration, and invasion of T24 cells and the possible associated mechanisms: expression of MMP-2 and MMP-9, and regulation of BCL-2 and BAX proteins. Methods T24 cells received corresponding treatments including vehicle control, antibody (20ng/mL CCR7 antibody and 50 ng/ml CCL21), and 50, 100, and 200 ng/ml...

β-Catenin Enhances Odontoblastic Differentiation of Dental Pulp Cells through Activation of Runx2

An intense stimulus can cause death of odontoblasts and initiate odontoblastic differentiation of stem/progenitor cell populations of dental pulp cells (DPCs), which is followed by reparative dentin formation. However, the mechanism of odontoblastic differentiation during reparative dentin formation remains unclear. This study was to determine the role of β-catenin, a key player...

TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality

, ChinaJue Wang, Tongjuan Li, Mi Zhou, Xiaoxi Zhou, Shiqiu Zhou, Na Wang, Liang Huang, Lei Zhao, Yang Cao, Min Xiao, Zhen Shang & Jianfeng ZhouCancer Biology Research Center, Tongji Hospital, Tongji Medical ... in:Nature Research journals • PubMed • Google ScholarSearch for Tongjuan Li in:Nature Research journals • PubMed • Google ScholarSearch for Mi Zhou in:Nature Research journals • PubMed • Google ScholarSearch

Testing a Conceptual Lumped Model in Karst Area, Southwest China

Karst aquifers are known for their heterogeneous physical properties and irregular complex flow patterns which make it a challenge to describe the hydrological behavior and to quantitatively define the distribution of river flow components using hydrologic models. In this paper, a conceptual lumped hydrologic model, Xin’anjiang model (XAJ), was applied in Sancha River, which is a...

Testing a Conceptual Lumped Model in Karst Area, Southwest China

Karst aquifers are known for their heterogeneous physical properties and irregular complex flow patterns which make it a challenge to describe the hydrological behavior and to quantitatively define the distribution of river flow components using hydrologic models. In this paper, a conceptual lumped hydrologic model, Xin’anjiang model (XAJ), was applied in Sancha River, which is a...

MicroRNA-92a Inhibition Attenuates Hypoxia/Reoxygenation-Induced Myocardiocyte Apoptosis by Targeting Smad7

Background MicroRNAs (miRNAs) regulate a lot of physiological and pathological processes, including myocardial ischemia/reperfusion. Recent studies reported that knockdown of miR-92a could attenuate ischemia/reperfusion-induced myocardial injury. In the present study, we examined the potential anti-apoptotic effects of miR-92a in a rat myocardiocyte cell line, and the possible...

Investigation of the Effect of Type 2 Diabetes Mellitus on Subgingival Plaque Microbiota by High-Throughput 16S rDNA Pyrosequencing

Diabetes mellitus is a major risk factor for chronic periodontitis. We investigated the effects of type 2 diabetes on the subgingival plaque bacterial composition by applying culture-independent 16S rDNA sequencing to periodontal bacteria isolated from four groups of volunteers: non-diabetic subjects without periodontitis, non-diabetic subjects with periodontitis, type 2 diabetic...

The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL

Unlike other transfer RNAs (tRNA)-modifying enzymes from the SPOUT methyltransferase superfamily, the tRNA (Um34/Cm34) methyltransferase TrmL lacks the usual extension domain for tRNA binding and consists only of a SPOUT domain. Both the catalytic and tRNA recognition mechanisms of this enzyme remain elusive. By using tRNAs purified from an Escherichia coli strain with the TrmL...

Coexistence of bacterial leucyl-tRNA synthetases with archaeal tRNA binding domains that distinguish tRNALeu in the archaeal mode

Leucyl-tRNA (transfer RNA) synthetase (LeuRS) is a multi-domain enzyme, which is divided into bacterial and archaeal/eukaryotic types. In general, one specific LeuRS, the domains of which are of the same type, exists in a single cell compartment. However, some species, such as the haloalkaliphile Natrialba magadii, encode two cytoplasmic LeuRSs, NmLeuRS1 and NmLeuRS2, which are...

Serum lipocalin-2 levels positively correlate with coronary artery disease and metabolic syndrome

Background The lipocalin-2 (LCN2) cytokine, primarily known as a protein of the granules of human neutrophils, has been recently reported to be implicated in metabolic and inflammatory disorders. This study was designed to evaluate the relationship between serum LCN2 levels and coronary artery disease (CAD). Methods Serum LCN2 levels of 261 in-patients who underwent coronary...

Serum A-FABP Is Increased and Closely Associated with Elevated NT-proBNP Levels in Type 2 Diabetic Patients Treated with Rosiglitazone

Background Adipocyte fatty acid-binding protein (A-FABP) has been shown to play important roles in the development of metabolic syndrome, diabetes, and cardiovascular diseases. In this study we investigated the possible role of A-FABP in the development of cardiac dysfunction related to rosiglitazone treatment. Methodology/Principal Findings A total of 84 patients with newly...