Most camera images are saved as 8-bit standard RGB (sRGB) compressed JPEGs. Even when JPEG compression is set to its highest quality, the encoded sRGB image has been significantly processed in terms of color and tone manipulation. This makes sRGB–JPEG images undesirable for many computer vision tasks that assume a direct relationship between pixel values and incoming light. For...
Introduction Accelerometers are commonly used to assess physical activity. Consumer activity trackers have become increasingly popular today, such as the Fitbit. This study aimed to compare the average number of steps per day using the wrist-worn Fitbit Flex and waist-worn ActiGraph (wGT3X-BT) in free-living conditions. Methods 104 adult participants (n = 35 males; n = 69 females...
When human fibroblasts take up plasma low density lipoprotein (LDL), its cholesterol is liberated in lysosomes and eventually reaches the endoplasmic reticulum (ER) where it inhibits cholesterol synthesis by blocking activation of SREBPs. This feedback protects against cholesterol overaccumulation in the plasma membrane (PM). But how does ER know whether PM is saturated with...
Goldstein Michael S Brown - Stay current on the latest in life science and biomedical research from eLife. Sign up for alerts at elife.elifesciences.org Identification of NPC1 as the target of U18666A ... to submit the work for publication. Competing interests: The authors declare that no competing interests exist. Grant reference Author Joseph L. Goldstein Michael S. Brown Jef K. De Brabander 518
Brown 0 Joseph L Goldstein 0 0 Department of Molecular Genetics, University of Texas Southwestern Medical Center , Dallas, Texas, 75390 , USA Background The octanoylated peptide ghrelin stimulates growth
and their all powerful sequencing machines. D Michael S. Brown and Joseph L. Goldstein are in the Department of Molecular Gen etics, University of Texas Southwestern Medical Center at Dallas, Dallas
This is a report of a pilot study conducted to examine patients
