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Search: authors:"Mie Kurata"

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Applications of reconstituted inflammasomes in a cell-free system to drug discovery and elucidation of the pathogenesis of autoinflammatory diseases

The inflammasome, typically consisting of a Nod-like receptor, apoptosis-associated speck-like protein, and pro-caspase-1, has recently been identified as a huge intracellular complex, which plays a crucial role in interleukin-1 maturation or specific physiological functions. Two Nod-like receptors, such as nucleotide-binding oligomerization domains-containing protein (Nod)1 and...

Neoatherosclerosis development following bioresorbable vascular scaffold implantation in diabetic and non-diabetic swine

, Dirk-Jan Duncker, Evelyn Regar, Heleen M. M. van Beusekom. Formal analysis: Nienke S. van Ditzhuijzen, Mie Kurata, Magdalena Murawska, Brett Bouma, Martin Villiger, Gijs van Soest, Evelyn Regar ... . Funding acquisition: Dirk-Jan Duncker, Heleen M. M. van Beusekom. Investigation: Nienke S. van Ditzhuijzen, Mie Kurata, Mieke van den Heuvel, Evelyn Regar, Heleen M. M. van Beusekom. Methodology: Nienke

Pathophysiology of Lung Injury Induced by Common Bile Duct Ligation in Mice

Background Liver dysfunction and cirrhosis affect vasculature in several organ systems and cause impairment of organ functions, thereby increasing morbidity and mortality. Establishment of a mouse model of hepatopulmonary syndrome (HPS) would provide greater insights into the genetic basis of the disease. Our objectives were to establish a mouse model of lung injury after common...