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Maternal cancer and congenital anomalies in children – a Danish nationwide cohort study

Several studies on pregnancy-associated cancers have suggested an association with congenital anomalies in offspring. Previous studies have included maternal cancers diagnosed up to 2 years after pregnancy; however, long latency periods of some cancers mean that cancers diagnosed many years postpartum might have been present during pregnancy in a preclinical state. This paper ...

Mortality in Children Aged 0-9 Years: A Nationwide Cohort Study from Three Nordic Countries

Background Mortality in children under five years has been widely studied, whereas mortality at 5–9 years has received little attention. Using unique data from national registers in three Nordic countries, we aimed to characterize mortality directionality in children aged 0 to 9 years. Methods and Findings The cohort study included all children born in Denmark from 1973 to 2008 (n ...

Parker et al. Respond to “Preeclampsia Risk After Induced Abortion”

Epidemiology, School of Public Health, Boston University , Boston, Massachusetts (Samantha E. Parker , Martha M. Werler); National Institute of Health and Welfare , Helsinki , Finland ( Mika Gissler); Nordic ... School of Public Health , Gothenburg , Sweden ( Mika Gissler); Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University , New York , New York (Cande V. Ananth); and

Influence of delivery characteristics and socioeconomic status on giving birth by caesarean section – a cross sectional study during 2000–2010 in Finland

Background Caesarean section (CS) rates especially without medical indication are rising worldwide. Most of indications for CS are relative and CS rates for various indications vary widely. There is an increasing tendency to perform CSs without medical indication on maternal request. Women with higher socioeconomic status (SES) are more likely to give birth by CS. We aimed to study ...

Prevalence of overweight in 2 to 17 year-old children and adolescents whose parents live separately: a Nordic cross-sectional study

Background Comparative data of parental separation and childhood overweight has not been available before across the Nordic countries. The aim of this study was to examine the within-country prevalence and association between parental cohabitation and overweight in Nordic children. Methods A cross-sectional survey of 2-17-year-old children was conducted in 2011, titled: ...

Unemployment at municipality level is associated with an increased risk of small for gestational age births � a multilevel analysis of all singleton births during 2005�2010 in Finland

Introduction Neighbourhood level deprivation has been shown to influence adverse perinatal outcomes independent of individual level socioeconomic status (SES) in countries with high income inequality, such as the United States. The present study evaluates whether municipality level deprivation defined based on education (proportion of inhabitants with university level education), ...

The Association of Episiotomy with Obstetric Anal Sphincter Injury–A Population Based Matched Cohort Study

Objectives To estimate the independent association of episiotomy with obstetric anal sphincter injuries (OASIS) using first a cross-sectional and then a matched pair analysis. Design A matched cohort. Setting Data was gathered from the Finnish Medical Birth Register from 2004–2011. Population All singleton vaginal births (n = 303,758). Methods Women resulting matched pairs (n = ...

Mortality after Parental Death in Childhood: A Nationwide Cohort Study from Three Nordic Countries

Jiong Li and colleagues examine mortality rates in children who lost a parent before 18 years old compared with those who did not using population-based data from Denmark, Sweden, and Finland. Please see later in the article for the Editors' Summary

An International Contrast of Rates of Placental Abruption: An Age-Period-Cohort Analysis

-reproductive-health/parturientsdeliveries-and-births/perinatal-statistics-parturientsdelivers-and-newborns Contact: Mika Gissler, THL National Institute for Health and Welfare, PO BOX 30, 00271 Helsinki, Finland

Contribution of Risk Factors to Extremely, Very and Moderately Preterm Births – Register-Based Analysis of 1,390,742 Singleton Births

Background Preterm birth, defined as birth occurring before 37 weeks gestation, is one of the most significant contributors to neonatal mortality and morbidity, with long-term adverse consequences for health, and cognitive outcome. Objective The aim of the present study was to identify risk factors of preterm birth (≤36+6 weeks gestation) among singleton births and to quantify the ...

Differences in perinatal and infant mortality in high-income countries: artifacts of birth registration or evidence of true differences?

Background Variation in birth registration criteria may compromise international comparisons of fetal and infant mortality. We examined the effect of birth registration practices on fetal and infant mortality rates to determine whether observed differences in perinatal and infant mortality rates were artifacts of birth registration or reflected true differences in health status. ...

Birth weight, gestational age, fetal growth and childhood asthma hospitalization

Background Childhood asthma may have a fetal origin through fetal growth and development of the immunocompetence or respiratory organs. Objective We examined to which extent short gestational age, low birth weight and fetal growth restriction were associated with an increased risk of asthma hospitalization in childhood. Methods We undertook a cohort study based on several national ...

Psychological Stress and Hospitalization for Childhood Asthma-a Nationwide Cohort Study in Two Nordic Countries

ObjectiveExposures to psychological stress in early life may contribute to the development or exacerbation of asthma. We undertook a cohort study based on data from several population-based registers in Denmark and Sweden to examine whether bereavement in childhood led to increased asthma hospitalization. MethodsAll singleton children born in Denmark during 1977-2008 and in Sweden ...

The risk of childhood autism among second-generation migrants in Finland: a case–control study

Background Studying second-generation immigrants can help in identifying genetic or environmental risk factors for childhood autism. Most previous studies have focused on maternal region of birth and showed inconsistent results. No previous study has been conducted in Finland. Methods The study was a nested case–control study based on a national birth cohort. Children born in ...

The Burden of OASIS Increases along with Socioeconomic Position – Register-Based Analysis of 980,733 Births in Finland

Background Obstetric anal sphincter injury (OASIS) has been identified as a major preventable risk factor for anal incontinence. Objective Aim was to measure national variation in incidence of OASIS by socioeconomic status (SES). Methods A retrospective population based case-control study using the data derived from the Finnish Medical Birth Register for the years 1991–2010. A ...

Varying gestational age patterns in cesarean delivery: an international comparison

2 11 Francisco Bolumar 7 11 Ashna Mohangoo 6 11 Mika Gissler 4 5 11 Katarzyna Szamotulska 9 11 Nicholas Lack 8 11 Jan Nijhuis 10 11 Petr Velebil 11 13 Luule Sakkeus 11 14 James Chalmers 11 12 Jennifer ... : Gerald Haidinger (Austria), Evelyne Martens (Flanders), Peter Velebil (Czech Republic), Luule Sakkeus (Estonia), Mika Gissler (Finland), Béatrice Blondel (France), Nicholas Lack, Björn Misselwitz, Paul

Contribution of socioeconomic status to the risk of small for gestational age infants – a population-based study of 1,390,165 singleton live births in Finland

Background Small for gestational age (SGA) infants are at increased risk of short- and long-term adverse outcomes. Methods Population-based case–control study using data derived from the Finnish Medical Birth Register for the years 1987–2010 (total population of singleton live births n = 1,390,165). The aim was to quantify the importance of risk factors for SGA and describe their ...

Relation of Prenatal Smoking Exposure and Use of Psychotropic Medication up to Young Adulthood

, Finland (Mika Gissler); Nordic School of Public Health, Gothenburg, Sweden (Mika Gissler); Department of Psychiatry, University of Turku, Turku, Finland (Jyrki Korkeila); and Department of Psychiatry

Infant and childhood neurodevelopmental outcomes following prenatal exposure to selective serotonin reuptake inhibitors: overview and design of a Finnish Register-Based Study (FinESSI)

) Heli Malm 0 1 Miia Artama Alan S Brown Mika Gissler David Gyllenberg Susanna Hinkka-Yli-Salomki Ian McKeague Andre Sourander 0 Department of Clinical Pharmacology, Helsinki University and Helsinki

Maternal and Perinatal Characteristics and the Risk of Cow's Milk Allergy in Infants up to 2 Years of Age: A Case-Control Study Nested in the Finnish Population

Welfare, National Institute for Health and Welfare, Helsinki, Finland (Annamari Lundqvist); Department of Information, National Institute for Health and Welfare, Helsinki, Finland (Mika Gissler); Department ... of Lifestyle and Participation, National Institute for Health and Welfare, Helsinki, Finland (Johanna Metsala, Suvi M. Virtanen); Nordic School of Public Health, Gothenburg, Sweden (Mika Gissler