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Parker et al. Respond to “Preeclampsia Risk After Induced Abortion”

Epidemiology, School of Public Health, Boston University , Boston, Massachusetts (Samantha E. Parker , Martha M. Werler); National Institute of Health and Welfare , Helsinki , Finland ( Mika Gissler); Nordic ... School of Public Health , Gothenburg , Sweden ( Mika Gissler); Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University , New York , New York (Cande V. Ananth); and

Uterine perforation caused by intrauterine devices: clinical course and treatment

STUDY QUESTIONS What are the symptoms of uterine perforation caused by modern copper intrauterine devices (Cu-IUDs) and the levonorgestrel-releasing intrauterine system (LNG-IUS); how is perforation detected and what are the findings in abdominal surgery?

Assisted reproduction using donated embryos: outcomes from surveillance systems in six countries†

BACKGROUND Embryo donation, though less often performed than other assisted reproductive technology (ART), can represent an attractive option for couples who do not wish to discard their embryos remaining after IVF, and for those who cannot or should not conceive naturally. Clinicians and potential participants could benefit from information comparing outcomes of embryo donation ...

Socioeconomic status affects the prevalence, but not the perinatal outcomes, of in vitro fertilization pregnancies

STUDY QUESTION Does maternal socioeconomic status (SES) confound or modify the association between IVF and perinatal outcome among singleton births?

Intrauterine contraception: incidence and factors associated with uterine perforation—a population-based study

STUDY QUESTION What are the incidence and factors associated with uterine perforation by modern copper intrauterine device (Cu-IUD) and the levonorgestrel-releasing intrauterine system (LNG-IUS)?

Relation of Prenatal Smoking Exposure and Use of Psychotropic Medication up to Young Adulthood

, Finland (Mika Gissler); Nordic School of Public Health, Gothenburg, Sweden (Mika Gissler); Department of Psychiatry, University of Turku, Turku, Finland (Jyrki Korkeila); and Department of Psychiatry

Can the outcome of the next pregnancy be predicted at the time of induced abortion?

BACKGROUND Factors predicting the outcome of the next pregnancy following termination of pregnancy (TOP) are poorly known. METHODS A cohort of 1269 women undergoing medical TOP between 2000 and 2002 were followed up until the next pregnancy or until the end of 2006, using registers of induced abortion, births and hospital discharges. Factors associated with repeat TOP, delivery and ...

Immediate adverse events after second trimester medical termination of pregnancy: results of a nationwide registry study

BACKGROUND Increasing gestational age is associated with an increased risk of complications in studies assessing surgical termination of pregnancy (TOP). Medical TOP is widely used during the second trimester and little is known about the frequency of complications. This epidemiological study was undertaken to assess the frequency of adverse events following the second trimester ...

Maternal and Perinatal Characteristics and the Risk of Cow's Milk Allergy in Infants up to 2 Years of Age: A Case-Control Study Nested in the Finnish Population

Welfare, National Institute for Health and Welfare, Helsinki, Finland (Annamari Lundqvist); Department of Information, National Institute for Health and Welfare, Helsinki, Finland (Mika Gissler); Department ... of Lifestyle and Participation, National Institute for Health and Welfare, Helsinki, Finland (Johanna Metsala, Suvi M. Virtanen); Nordic School of Public Health, Gothenburg, Sweden (Mika Gissler

Treatment for cervical intraepithelial neoplasia and subsequent IVF deliveries

BACKGROUND The aim was to study whether the treatment of cervical intraepithelial neoplasia (CIN) is associated with a subsequent increase in the use of IVF to achieve deliveries and whether women with cervical treatment and IVF have increased rates of preterm delivery. METHODS This was a register-based retrospective cohort (n = 822 183 deliveries) study from Finland whose main ...

Perinatal Factors and the Risk of Asthma in Childhood—A Population-based Register Study in Finland

The aim of the study was to assess whether perinatal factors are associated with the risk of asthma in childhood in a register-based, nested case-control study in Finland. All children born between January 1, 1996, and April 30, 2004, who were entitled to a special reimbursement for antiasthmatic drugs (i.e., had diagnosed asthma by 2006 and had purchased inhaled corticosteroids or ...

Complications of IVF and ovulation induction

BACKGROUND: The frequency and importance of complications of IVF and other ovulation induction (OI) are poorly known. We examined the occurrence of serious complications and miscarriages leading to hospitalization or operation after IVF (including microinjections and frozen embryo transfers) and OI treatment (with or without insemination). METHODS: Women who received IVF (n = 9175) ...

Comparison of perinatal health of children born from IVF in Finland in the early and late 1990s

BACKGROUND: The purpose of this study was to investigate whether perinatal health outcomes changed during the 1990s with the increasing use of IVF. METHODS: Data were from the Finnish Medical Birth Register for periods 1991–1993 and 1998–1999. Outcomes of IVF infants and other infants were compared, both overall and separately for singleton and multiple births, by adjusting for ...

Post-neonatal hospitalization and health care costs among IVF children: a 7-year follow-up study

BACKGROUND The objective of this study was to evaluate whether the post-neonatal hospitalization and resulting health care costs are increased among in vitro fertilization (IVF) children up to 7 years of age. METHODS We conducted a population-based cohort study with linkage to a national hospital discharge register including 303 IVF children, born from 1990 to 1995, and 567 control ...

Obstetric and perinatal outcome of pregnancies after intrauterine insemination

The main aim of this study was to evaluate the obstetric and perinatal outcome of pregnancies after intrauterine insemination (IUI) with the partner's spermatozoa combined with ovarian stimulation. Information concerning the antenatal care and obstetric and perinatal outcome of IUI pregnancies (n = 111), spontaneous (n = 333) and in-vitro fertilization (IVF) (n = 333) was obtained ...

Neonatal outcome and congenital malformations in children born after in-vitro fertilization

BACKGROUND: To evaluate the neonatal outcome and the prevalence of congenital malformations in children born after IVF in northern Finland we carried out a population-based study with matched controls. METHODS: Firstly, 304 IVF children born in 1990–1995 were compared with 569 controls, representing the general population in proportion of multiple births, randomly chosen from the ...

The course of pregnancy and delivery and the use of maternal healthcare services after standard IVF in Northern Finland 1990–1995

BACKGROUND: The objective of this study was to evaluate the course of pregnancy and delivery and the use of maternal healthcare after IVF. METHODS: This population-based cohort study included all women who had undergone IVF treatment in Northern Finland leading to delivery in 1990–1995 (n = 225) and control pregnancies derived from the Finnish Medical Birth Register (n = 671) ...