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49 papers found.
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Associations of DNMT3B −149C>T and −2437T>A polymorphisms and lung cancer risk in Chinese population

Background DNMT3B polymorphisms are associated with the susceptibility of lung cancer. DNMT3B −2437T>A is a novel polymorphism, and its influence on the risk of lung cancer in Chinese was investigated in this study. In addition, effect of DNMT3B −149C>T polymorphism on lung cancer was also explored. Methods Genotyping in subjects were performed by PCR-RFLP. Haplotype frequencies ...

Existence of convex solutions for systems of Monge-Ampère equations

We study the existence, multiplicity, and nonexistence of convex solutions for systems of Monge-Ampère equations with multiparameters. The proof of the results is based on the method of upper and lower solutions and the fixed point index theory.

Unsupervised background-constrained tank segmentation of infrared images in complex background based on the Otsu method

; Min Gao, FG; Dan Fang, ES; Baoquan Zhang, ES. All authors read and approved the final manuscript. Acknowledgements This work is supported by Postdoctoral Science Foundation of China (Grant No

Scale adaptive compressive tracking

Recently, the compressive tracking (CT) method (Zhang et al. in Proceedings of European conference on computer vision, pp 864–877, 2012) has attracted much attention due to its high efficiency, but it cannot well deal with the scale changing objects due to its constant tracking box. To address this issue, in this paper we propose a scale adaptive CT approach, which adaptively ...

Compromised Wound Healing in Ischemic Type 2 Diabetic Rats

Ischemia is one of the main epidemic factors and characteristics of diabetic chronic wounds, and exerts a profound effect on wound healing. To explore the mechanism of and the cure for diabetic impaired wound healing, we established a type 2 diabetic rat model. We used an 8weeks high fat diet (HFD) feeding regimen followed by multiple injections of streptozotocin (STZ) at a dose of ...

Transcriptome characterization of three wild Chinese Vitis uncovers a large number of distinct disease related genes

Background Grape is one of the most valuable fruit crops and can serve for both fresh consumption and wine production. Grape cultivars have been selected and evolved to produce high-quality fruits during their domestication over thousands of years. However, current widely planted grape cultivars suffer extensive loss to many diseases while most wild species show resistance to ...

Collimator rotation in volumetric modulated arc therapy for craniospinal irradiation and the dose distribution in the beam junction region

Purpose The purpose of this study was to investigate the role of beam collimator rotation in Volumetric Modulated Arc Therapy (VMAT) for craniospinal irradiation (CSI), and the impact on dose distribution in the beam junctions. Methods Six adult patients were selected for the study. Six VMAT plans with different collimator angles were generated for each patient. The patients were ...

Temperature characteristics and error compensation for quartz flexible accelerometer

. Compared with methods in [11-15], the differential conduction model and weighted average model are more favorable in practical application. Jing-Min Gao received the B. Sc. and M. Sc. degrees in hydraulic

Forecast of the incidence, prevalence and burden of end-stage renal disease in Nanjing, China to the Year 2025

Background There are limited data on the trends of incidence or prevalence of end stage renal disease (ESRD) in China. To assist in future planning for the ESRD program, the trends of incidence, prevalence and health care costs were analyzed and forecasted to the year 2025 by modeling of historical data from 2004 through 2014. Methods Nanjing urban employee basic medical insurance ...

Item Anomaly Detection Based on Dynamic Partition for Time Series in Recommender Systems

In recent years, recommender systems have become an effective method to process information overload. However, recommendation technology still suffers from many problems. One of the problems is shilling attacks-attackers inject spam user profiles to disturb the list of recommendation items. There are two characteristics of all types of shilling attacks: 1) Item abnormality: The ...

Shilling Attacks Detection in Recommender Systems Based on Target Item Analysis

Recommender systems are highly vulnerable to shilling attacks, both by individuals and groups. Attackers who introduce biased ratings in order to affect recommendations, have been shown to negatively affect collaborative filtering (CF) algorithms. Previous research focuses only on the differences between genuine profiles and attack profiles, ignoring the group characteristics in ...

An evaluation of vehicular networks with real vehicular GPS traces

Vehicular networks have attracted increasing attention from both the academy and industry. Applications of vehicular networks require efficient data communications between vehicles, whose performance is concerned with delivery ratio, delivery delay, and routing cost. The most previous work of routing in vehicular networks assumes oversimplified node mobility when evaluating the ...

Clinical Characteristics and Molecular Epidemiology of Noroviruses in Outpatient Children with Acute Gastroenteritis in Huzhou of China

Background Noroviruses (NoVs) are considered major causative pathogens associated with the morbidity and mortality of young children with acute gastroenteritis. However, few studies have examined NoVs causing acute diarrhea among outpatient children worldwide. This study was conducted to investigate the clinical features and molecular epidemiology of NoVs in outpatient children ...

Prevalence of Veterinary Antibiotics and Antibiotic-Resistant Escherichia coli in the Surface Water of a Livestock Production Region in Northern China

This study investigated the occurrence of 12 veterinary antibiotics (VAs) and the susceptibility of Escherichia coli (E. coli) in a rural water system that was affected by livestock production in northern China. Each of the surveyed sites was determined with at least eight antibiotics with maximum concentration of up to 450 ng L−1. The use of VAs in livestock farming probably was a ...

Prolonging Survival of Corneal Transplantation by Selective Sphingosine-1-Phosphate Receptor 1 Agonist

Corneal transplantation is the most used therapy for eye disorders. Although the cornea is somewhat an immune privileged organ, immune rejection is still the major problem that reduces the success rate. Therefore, effective chemical drugs that regulate immunoreactions are needed to improve the outcome of corneal transplantations. Here, a sphingosine-1-phosphate receptor 1 (S1P1) ...

Upregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells

Background microRNA-122 (miR-122) is the most abundant and specific miRNA in the liver. It acts as an important tumor suppressor in hepatocellular carcinoma (HCC) through regulating its target genes, but details of its own regulation are largely unknown. Farnesoid X receptor (FXR), a transcription factor with multiple functions, plays an important role in protecting against liver ...

Epidemiological Study of RRT-Treated ESRD in Nanjing - A Ten-Year Experience in Nearly Three Million Insurance Covered Population

Background The growing burden of end-stage renal disease (ESRD) has been a great challenge to the health care system of China. However, the exact epidemiological data for ESRD in China remain unclear. We aimed to investigate the epidemiology of ESRD treated by renal replacement therapy (RRT) in Nanjing based on analysing ten-year data of Nanjing three million insurance covered ...

An ShRNA Based Genetic Screen Identified Sesn2 as a Potential Tumor Suppressor in Lung Cancer via Suppression of Akt-mTOR-p70S6K Signaling

Background Lung cancer is emerging rapidly as the leading death cause in Chinese cancer patients. The causal factors for Chinese lung cancer development remain largely unclear. Here we employed an shRNA library-based loss-of-function screen in a genome-wide and unbiased manner to interrogate potential tumor suppressor candidates in the immortalized human lung epithelial cell line ...