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Analytical Compliance Modeling of Serial Flexure-Based Compliant Mechanism Under Arbitrary Applied Load

kinematic parallel machine, and compliant mechanism. E-mail: . Tie-Min Li, born in 1971, is currently an associate research fellow at Manufacturing Engineering Institute, Department of Mechanical Engineering

Cellular microparticles and pathophysiology of traumatic brain injury

factor; TGF-β, transforming growth factor-β COMPLIANCE WITH ETHICS GUIDELINES Zilong Zhao, Yuan Zhou, Ye Tian, Min Li, Jing-fei Dong, and Jianning Zhang declare that they have no conflict of interest. All

Precise orbit determination of the Fengyun-3C satellite using onboard GPS and BDS observations

The GNSS Occultation Sounder instrument onboard the Chinese meteorological satellite Fengyun-3C (FY-3C) tracks both GPS and BDS signals for orbit determination. One month’s worth of the onboard dual-frequency GPS and BDS data during March 2015 from the FY-3C satellite is analyzed in this study. The onboard BDS and GPS measurement quality is evaluated in terms of data quantity as ...

Effects of a fixed low-dose ropivacaine with different volume and concentrations on interscalene brachial plexus block: a randomized controlled trial

Background Ultrasound guidance has reduced the amount of local anesthetics to achieve a successful block. Previous studies of the relationship between the volume or concentration of local anesthetics and the effects of the block were based on relatively high doses of local anesthetics. We tested the hypothesis that providing low dose of ropivacaine at three combinations of volumes ...

Overexpression of A613T and G462T variants of DNA polymerase β weakens chemotherapy sensitivity in esophageal cancer cell lines

variant of DNA polymerase β that is found in Esophageal Carcinoma patients impairs polymerase activity and BER . Sci Rep. 2015 ; 5 : 15986 . 20. Feng L , Ma Y , Zhao G , Min Li , Sun S , Dong Z , et al

Dexmedetomidine versus remifentanil for sedation during awake intubation using a Shikani optical stylet: a randomized, double-blinded, controlled trial

Background The purpose of this study was to compare the efficacy and safety of dexmedetomidine versus remifentanil for sedation during awake intubation using a Shikani optical stylet (SOS). Methods Sixty-eight patients with cervical trauma or severe cervical spondylosis undergoing cervical spinal surgery were enrolled in this prospective study. They were randomly assigned to ...

Blockage of glycolysis by targeting PFKFB3 suppresses tumor growth and metastasis in head and neck squamous cell carcinoma

Background Many cancers including head and neck squamous cell carcinoma (HNSCC) are characterized by a metabolic rewiring with increased glucose uptake and lactate production, termed as aerobic glycolysis. Targeting aerobic glycolysis presents a promising strategy for cancer therapy. This study investigates the therapeutic potential of glycolysis blockage by targeting ...

Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature

A review of studies on the body fluid levels of neuroactive amino acids, including glutamate, glutamine, taurine, gamma-aminobutyric acid (GABA), glycine, tryptophan, d-serine, and others, in autism spectrum disorders (ASD) is given. The results reported in the literature are generally inconclusive and contradictory, but there has been considerable variation among the previous ...

Para-amino benzoic acid doped micro-grooved carbon fibers to improve strength and biocompatibility of PLA-PEG

characterization of carbon-based materials and their applications in biological fields. Min Li was born in 1992. She received her BSc degree in material science and engineering from Huaqiao University in 2014. She

Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway

Background Mycoplasma ovipneumoniae (M. ovipneumoniae) is a species of Mycoplasma bacteria that specifically infects sheep and goat, causing ovine infectious pleuropneumonia. However, the mechanism underlying the pathogen-host interaction between M. ovipneumoniae and airway epithelial cells is unknown. Methods A primary air-liquid interface (ALI) epithelial culture model generated ...

FLEXc: protein flexibility prediction using context-based statistics, predicted structural features, and sequence information

Background The fluctuation of atoms around their average positions in protein structures provides important information regarding protein dynamics. This flexibility of protein structures is associated with various biological processes. Predicting flexibility of residues from protein sequences is significant for analyzing the dynamic properties of proteins which will be helpful in ...

Predicting essential proteins based on subcellular localization, orthology and PPI networks

Background Essential proteins play an indispensable role in the cellular survival and development. There have been a series of biological experimental methods for finding essential proteins; however they are time-consuming, expensive and inefficient. In order to overcome the shortcomings of biological experimental methods, many computational methods have been proposed to predict ...

Serum proteomic-based analysis identifying autoantibodies against PRDX2 and PRDX3 as potential diagnostic biomarkers in nasopharyngeal carcinoma

‑Sheng Huang Chao‑Qun Hong TianT‑ian Zhai Lian‑Di Liao WenJ‑ie Lin LiY‑an Xu Kai Zhang En‑Min Li Yu‑Hui Peng 0 0 Department of Clinical Laboratory Medicine, The Cancer Hospital of Shantou University

Relationship between fasting glucose levels and in-hospital mortality in Chinese patients with acute myocardial infarction and diabetes mellitus: a retrospective cohort study

Background Previous studies have demonstrated that elevated admission and fasting glucose (FG) is associated with worse outcomes in patients with acute myocardial infarction (AMI). However, the quantitative relationship between FG levels and in-hospital mortality in patients with AMI remains unknown. The aim of the study is to assess the prevalence of elevated FG levels in ...

The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling

Background With more than 600,000 mortalities each year, colorectal cancer (CRC) is the third most commonly diagnosed type of cancer worldwide. Recently, mechanisms involving noncoding RNAs have been implicated in the development of CRC. Methods We examined expression levels of lncRNA CRNDE and miR-181a-5p in 64 cases of CRC tissues and cell lines by qRT-PCR. Gain-of-function and ...

Incidence and age and gender profiles of hyperplasia in individual cervical vertebrae

2Department of Radiology, Taian City Central Hospital, Shandong Province, China *Min Li and Shuyong Liu are the co-first authors of this article. with patients becoming progressively younger.2,3 Cervical

Histone variants: the artists of eukaryotic chromatin

The eukaryotic genome is packaged into a complex nucleoprotein structure named chromatin, balancing the compactness of genome and the accessibility of regulatory proteins and RNA polymerases to DNA. The mechanisms of the regulation of chromatin dynamics include the post-translational modification of histones, alteration of nucleosome positions by chromatin remodelers, replacement ...

The Psychometric Evaluation of the Connor-Davidson Resilience Scale Using a Chinese Military Sample

psychology, College of Psychology, Third Military Medical University , Chongqing , China 1 Funding: This study was financially supported by National Natural Science Foundation of China granted to Min Li (No ... . 31170994) and Project of Military Research Foundation of PLA of China to Min Li , No. CWS11J049 2 Editor: Soraya Seedat, University of Stellenbosch, SOUTH AFRICA This study examined the psychometric