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Effects of Type 2 Diabetic Serum on Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells

Diabetic patients have an increased risk of osteoporosis-associated fractures. However, the results of most studies of the effects of diabetes on bone mass in patients with type 2 diabetes (T2DM) have been contradictory. To clarify these conflicting findings, we investigated the effects of diabetic serum on the proliferation and osteogenic differentiation of mesenchymal stem...

Ratio of Creatine Kinase to Alanine Aminotransferase as a Biomarker of Acute Liver Injury in Dystrophinopathy

Objective. To investigate the ratios of creatine kinase (CK) to aminotransferases as biomarkers of acute liver injury in dystrophinopathy. Methods. C57 and mdx (dystrophic) mice were treated with a hepatotoxic reagent D-galactosamine (D-GalN). The degrees of liver and muscle injury were assessed using histological examinations. To examine whether serum CK-adjusted...

Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells

Chen, Min Xu, Joseph A. Garcia. Formal analysis: Rui Chen, Min Xu, Jason Nagati, Joseph A. Garcia. Funding acquisition: Joseph A. Garcia. Investigation: Rui Chen, Min Xu, Jason Nagati, Joseph A

Diagnostic delay and mortality of active tuberculosis in patients after kidney transplantation in a tertiary care hospital in China

, Baishu Zhong, Haiyan Lou, Jun Li and Zhaoming Wang etc. Author Contributions Conceptualization: Wei Wu, Kaijin Xu. Data curation: Meifang Yang, Min Xu, Cheng Ding. Formal analysis: Cheng Ding ... . Investigation: Wei Wu, Min Xu, Yongtao Li, Kaijin Xu. Methodology: Wei Wu, Kaijin Xu. Project administration: Wei Wu, Kaijin Xu, Jifang Shen. Software: Cheng Ding. Supervision: Wei Wu, Jifang Shen, Lanjuan Li

Architecture of SWI/SNF chromatin remodeling complex

Zhang. Na Yang and Rui-min Xu provided the nucleosome core particles (NCP). Zhihui Zhang reconstructed the 3D structures under stain of SWI/SNF-NCP assembly and the SWI/SNF deletion mutants. Xuejuan Wang ... Wang, Jiyu Xin, Zhenrui Ding, Sheng Liu, Qianglin Fang, Na Yang, Rui-min Xu, Gang Cai declare that they have no conflict of interest. This article does not contain any studies with human or animal

Elaphroporia ailaoshanensis gen. et sp. nov. in Polyporales (Basidiomycota)

A new poroid wood-inhabiting fungal genus, Elaphroporia, typified by E. ailaoshanensis sp. nov., is proposed based on a combination of morphological features and molecular evidence. The genus is characterised by an annual growth habit, resupinate basidiocarps, becoming rigid and light-weight up on drying, a monomitic hyphal system with thick-walled generative hyphae bearing both...

Effect of particle size distribution on the correlation between liquefaction resistance and shear wave velocity of granular soils

Shear wave method has been increasingly popular in assessing the liquefaction potential of granular soils. Two particle-scale parameters, the inter-particle friction and the shear modulus of grains, play vital roles in correlation between Cyclic Resistance Ratio (CRR) and shear wave velocity corrected by overburden stress (Vs1). Series of drained one-dimensional compression tests...

Low temperature plasma promoting fibroblast proliferation by activating the NF-κB pathway and increasing cyclinD1 expression

Equipment, School of Electrical Engineering, Xi’an Jiaotong University, Xi’an, Shaanxi, 710049, ChinaGui-Min Xu & Guan-Jun Zhang AuthorsSearch for Jin-Ren Liu in:Nature Research journals • PubMed • Google ... Scholar Search for Gui-Min Xu in:Nature Research journals • PubMed • Google Scholar Search for Xing-Min Shi in:Nature Research journals • PubMed • Google Scholar Search for Guan-Jun Zhang in:Nature

Intermittent High Glucose Exacerbates A-FABP Activation and Inflammatory Response through TLR4-JNK Signaling in THP-1 Cells

Gan Huang,2 Jun-Mei Xu,1 Ai-Min Xu,3 Zhi-Guang Zhou,2 and Ru-Ping Dai1 1Department of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China 2Department of Metabolism

New Look at Nonlinear Aerodynamics in Analysis of Hypersonic Panel Flutter

A simply supported plate fluttering in hypersonic flow is investigated considering both the airflow and structural nonlinearities. Third-order piston theory is used for nonlinear aerodynamic loading, and von Karman plate theory is used for modeling the nonlinear strain-displacement relation. The Galerkin method is applied to project the partial differential governing equations...

Investigation of the deterioration of passive films in H2S-containing solutions

The effect of H2S on the corrosion behavior of 316L stainless steel was investigated using electrochemical methods by changing the gas condition from CO2 to H2S and then back to CO2. The presence of H2S showed an acceleration effect on the corrosion of 316L stainless steel in comparison with CO2. The acceleration effect remained even after the complete removal of H2S by CO2...

Diagnosis of the phase function of random media from light reflectance

, CT 06824, USAMin Xu AuthorsSearch for Min Xu in:Nature Research journals • PubMed • Google Scholar Contributions M.X. conceived the idea, performed numerical simulations, and wrote the manuscript ... . Competing interests The author declares no competing financial interests. Corresponding author Correspondence to Min Xu. Supplementary information PDF files1.Supplementary Information Rights and

Simulating cryo electron tomograms of crowded cell cytoplasm for assessment of automated particle picking

Background Cryo-electron tomography is an important tool to study structures of macromolecular complexes in close to native states. A whole cell cryo electron tomogram contains structural information of all its macromolecular complexes. However, extracting this information remains challenging, and relies on sophisticated image processing, in particular for template-free particle...

Effect of intravenous immunoglobulin on the function of Treg cells derived from immunosuppressed mice with Pseudomonas aeruginosa pneumonia

Aim The present study aimed to investigate the effect of intravenous immunoglobulin (IVIG) on regulatory T (Treg) cells derived from immunosuppressed mice with Pseudomonas aeruginosa (PA) pneumonia. Methods A total of 108 BALB/c mice were randomly divided into the following groups: control group (Control), immunosuppressed group (IS), PA pneumonia group (PA), PA pneumonia in...

Kinship Verification Using Facial Images by Robust Similarity Learning

October 2015; Accepted 12 January 2016 Academic Editor: Oscar Reinoso Copyright © 2016 Min Xu and Yuanyuan Shang. This is an open access article distributed under the Creative Commons Attribution License

Attachment strength of the subtidal seaweed Sargassum horneri (Turner) C. Agardh varies among development stages and depths

Sargassum horneri is one of the most important contributors to the rafts of floating seaweed in the waters off the coasts of northeastern Asia. These rafts serve as spawning and nursery grounds for many marine organisms, including Japanese saury and yellowtail. Thus, the details of the attachment/detachment mechanisms of S. horneri are of commercial significance for the...

Attentional deployment impacts neural response to regret

Li Zheng in:Nature Research journals • PubMed • Google ScholarSearch for Min Xu in:Nature Research journals • PubMed • Google ScholarSearch for Fanzhi Anita Zhou in:Nature Research journals • PubMed ... the data. Z.L., L.L., X.G., L.Z. M.X. and F.Z. wrote the manuscript. Competing interests The authors declare no competing financial interests. Corresponding authors Correspondence to Min Xu or Xiuyan

Solid oxide fuel cell interconnect design optimization considering the thermal stresses

The mechanical failure of solid oxide fuel cell (SOFC) components may cause cracks with consequences such as gas leakage, structure instability and reduction of cell lifetime. A comprehensive 3D model of the thermal stresses of an anode-supported planar SOFC is presented in this work. The main objective of this paper is to get an interconnect optimized design by evaluating the...

Localizing Age-Related Changes in Brain Structure Using Voxel-Based Morphometry

Aim. We report the dynamic anatomical sequence of human cortical gray matter development from late childhood to young adults using VBM and ROI-based methods. Method. The structural MRI of 91 normal individuals ranging in age from 6 to 26 years was obtained and the GMV for each region was measured. Results. Our results showed that the earliest loss of GMV occurred in left...