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Network meta-analysis of treatment regimens for inoperable advanced hepatocellular carcinoma with portal vein invasion

Network meta-analysis of treatment regimens for inoperable advanced hepatocellular carcinoma with portal vein invasion Ming-Feng Li,1,2,* Henry WC Leung,3,* Agnes LF Chan,4 Shyh-Yau Wang2 ... of Medical imaging, Buddhist Tzu-Chi general hospital , hualien , Taiwan 5 Ming-Feng li 6 Department of Pharmacy, a n-n an hospital, China Medical University , Tainan , Taiwan PowerdbyTCPDF

The Indonesian throughflow, its variability and centennial change

The Indonesian Throughflow (ITF) is an important component of the upper cell of the global overturning circulation that provides a low-latitude pathway for warm, fresh waters from the Pacific to enter the Indian Ocean. Variability and changes of the ITF have significant impacts on Indo-Pacific oceanography and global climate. In this paper, the observed features of the ITF and...

A review of beam pumping energy-saving technologies

The beam pumping units applied in oilfield for more than 150 years, because it had the advantages of simple structure, reliable and durable. At present, it is still one of the most important artificial lift methods in the world. Due to the inherent structure of the beam pumping units, the balanced torque curve of gearbox has a bigger fluctuation ratio and negative torque that...

Characteristics and risk factors for inconsistency between the risk of exacerbations and the severity of airflow limitation in COPD based on GOLD 2017: A retrospective, cross-sectional study

fees from Novartis Pharmaceuticals Corporation while the authors, Ming-Feng Wu and Hui-Chen Chen, declare that they have no competing interests. However, this does not alter our adherence to PLOS ONE ... , Chiayi, Taiwan 11Chang Gung Memorial Hospital, Kaohsiung, Taiwan 12E-DA Hospital, Kaohsiung, Taiwan Author Contributions Conceptualization: Wei-Chang Huang, Ming-Feng Wu, Hui-Chen Chen, Jeng-Yuan Hsu

Processing of high-precision ceramic balls with a spiral V-groove plate

As the demand for high-performance bearings gradually increases, ceramic balls with excellent properties, such as high accuracy, high reliability, and high chemical durability used, are extensively used for highperformance bearings. In this study, a spiral V-groove plate method is employed in processing high-precision ceramic balls. After the kinematic analysis of the ball-spin...

A prospective, observational study of patients with uncommon distal symmetric painful small-fiber neuropathy

Huang, Long-Sun Ro. Data curation: Ming-Feng Liao. Funding acquisition: Long-Sun Ro. Investigation: Ming-Feng Liao, Hui-Ching Hsu, Yi-Ching Weng, Ai-Lun Lo, Kuo-Hsuan Chang, Hong-Shiu Chang, Hung-Chou

The impact of predisposing, enabling, and need factors in utilization of health services among rural residents in Guangxi, China

Background Healthcare in China has significantly improved, meanwhile many  socio-economic risk factors and health conditions factors affect accessibility and utilization of health services in rural areas. Inequity of health service in China needs to  be estimated and reduced. Andersen behavioral model is useful to assess the association of health service utilization with...

Postoperative prophylactic hepatic arterial infusion chemotherapy for stage III colorectal cancer: a retrospective study

Postoperative prophylactic hepatic arterial infusion chemotherapy for stage Ⅲ colorectal cancer: a retrospective study Yao Wang,1 Xin Rong Sun,1 Wen Ming Feng,1 Ying Bao,1 Yin Yuan Zheng2 1Department

JMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner

JMJD6, a jumonji C (Jmj C) domain-containing protein demethylase and hydroxylase, has been implicated in an array of biological processes. It has been shown that JMJD6 interacts with and hydroxylates multiple serine/arginine-rich (SR) proteins and SR related proteins, including U2AF65, all of which are known to function in alternative splicing regulation. However, whether JMJD6...

Assessment of potential factors associating with costs of hospitalizing cardiovascular diseases in 141 hospitals in Guangxi, China

Background The rising cost of healthcare is of great concern in China, as evidenced by the media features negative reports almost daily. However there are only a few studies from well-developed cities, like Beijing or Shanghai, and little is known about healthcare costs in rest of the country. In this study, we use hospitalization summary reports (HSRs) from admitted...

Multi-center study on patient selection for and the oncologic safety of intraoperative radiotherapy (IORT) with the Xoft Axxent® eBx® System for the management of early stage breast cancer in Taiwan

for their assistance of this study. Author Contributions Conceptualization: Hung-Wen Lai, Ming-Feng Hou, Fang-Ming Chen. 11 / 13 Data curation: Liang-Chih Liu, Fu Ouyang, Chung-Chin Yao, Hsiang-Chun ... , Yao-Chung Wu, Hung-Bun Lam, Fang-Ming Chen. Funding acquisition: Hung-Wen Lai. Investigation: Yao-Chung Wu, Po-Sheng Yang. Methodology: Hung-Wen Lai, Yen-Dun Tzeng, Ming-Feng Hou. Project

The Role of the Two-Component System BaeSR in Disposing Chemicals through Regulating Transporter Systems in Acinetobacter baumannii

Bacterial two-component regulatory systems (TCSs) facilitate changes in gene expression in response to environmental stimuli. TCS BaeR regulons influence tigecycline susceptibility in Acinetobacter baumannii through positively regulating the pump genes adeA and adeB. In this study, we demonstrate that an additional two transport systems, AdeIJK and MacAB-TolC, are also regulated...

Highly sensitive detection of the PIK3CA H1047R mutation in colorectal cancer using a novel PCR-RFLP method

Background The PIK3CA H1047R mutation is considered to be a potential predictive biomarker for EGFR-targeted therapies. In this study, we developed a novel PCR-PFLP approach to detect the PIK3CA H1047R mutation in high effectiveness. Methods A 126-bp fragment of PIK3CA exon-20 was amplified by PCR, digested with FspI restriction endonuclease and separated by 3 % agarose gel...

Influence of Ethnicity on the Accuracy of Non-Invasive Scores Predicting Non-Alcoholic Fatty Liver Disease

Objectives Presence of non-alcoholic fatty liver disease (NAFLD) can predict risks for diabetes, cardiovascular disease and advanced liver disease in the general population. We aimed to establish a non-invasive score for prediction of NAFLD in Han Chinese, the largest ethnic group in the world, and detect whether ethnicity influences the accuracy of such a score. Methods Liver...

OmpA Binding Mediates the Effect of Antimicrobial Peptide LL-37 on Acinetobacter baumannii

Multidrug-resistant Acinetobacter baumannii has recently emerged as an important pathogen in nosocomial infection; thus, effective antimicrobial regimens are urgently needed. Human antimicrobial peptides (AMPs) exhibit multiple functions and antimicrobial activities against bacteria and fungi and are proposed to be potential adjuvant therapeutic agents. This study examined the...

Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells

Background Saikosaponin d (SSd) is one of the main active triterpene saponins in Bupleurum falcatum. It has a steroid-like structure, and is reported to have pharmacological activities, including liver protection in rat, cell cycle arrest and apoptosis induction in several cancer cell lines. However, the biological functions and molecular mechanisms of mammalian cells under SSd...

Quality of Life Is Related to Social Support in Elderly Osteoporosis Patients in a Chinese Population

Objective To explore the association between quality of life and social support in elderly osteoporosis patients in a Chinese population. Methods A total of 214 elderly patients who underwent bone mineral density screening were divided into two groups: elderly patients with primary osteoporosis (case group, n = 112) and normal elderly patients (control group, n = 102). Quality of...

In Situ Regeneration of Si-based ARROW-B Surface Plasmon Resonance Biosensors

Si-based antiresonant reflecting optical waveguide type B (ARROW-B) surface plasmon resonance (SPR) biosensors allow label-free high-sensitivity detection of biomolecular interactions in real time. The ARROW-B waveguide, which has a thick guiding layer, provides efficient coupling with a single-mode fiber. The Si-based ARROW-B SPR biosensors were fabricated by using the standard...

Cloud-Based Service Information System for Evaluating Quality of Life after Breast Cancer Surgery

Objective Although recent studies have improved understanding of quality of life (QOL) outcomes of breast conserving surgery, few have used longitudinal data for more than two time points, and few have examined predictors of QOL over two years. Additionally, the longitudinal data analyses in such studies rarely apply the appropriate statistical methodology to control for...