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Impact of silencing hepatic SREBP-1 on insulin signaling

. Data curation: Victoria Jideonwo, Yongyong Hou, Miwon Ahn, Sneha Surendran. Formal analysis: Victoria Jideonwo, NuÂria Morral. Project administration: NuÂria Morral. Supervision: NuÂria Morral ... . Writing ± original draft: Victoria Jideonwo. Writing ± review & editing: Victoria Jideonwo, Yongyong Hou, Miwon Ahn, Sneha Surendran, NuÂria Morral. 9 / 12 10 / 12 11 / 12 1. Alessi DR , James SR , Downes

The p21-activated kinase (PAK1) is involved in diet-induced beta cell mass expansion and survival in mice and human islets

for disease intervention. Beta cell mass; Diet-induced obesity; Insulin secretion; PAK1; Prediabetes; Type 2 diabetes - Miwon Ahn and Stephanie M. Yoder contributed equally to this study