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Assessment of physical inactivity and locomotor dysfunction in adults with visual impairment

role in the design or completion of this research. Author information AffiliationsDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, JapanSachiko Inoue, Motoko Kawashima & Kazuo ... Search for Motoko Kawashima in:Nature Research journals • PubMed • Google Scholar Search for Yoshimune Hiratsuka in:Nature Research journals • PubMed • Google Scholar Search for Tadashi Nakano in:Nature

Strengths use as a secret of happiness: Another dimension of visually impaired individuals' psychological state

acknowledge the assistance of Editage (http://www.editage.jp) with the English language editing of this manuscript. Author Contributions Conceptualization: Shinichiro Matsuguma, Motoko Kawashima. Data ... curation: Shinichiro Matsuguma. Formal analysis: Shinichiro Matsuguma, Fumiya Sano. Funding acquisition: Motoko Kawashima, Kazuo Tsubota. Investigation: Shinichiro Matsuguma, Motoko Kawashima

Possible association between subtypes of dry eye disease and seasonal variation

Possible association between subtypes of dry eye disease and seasonal variation Masahiko Ayaki, Motoko Kawashima, Miki Uchino, Kazuo Tsubota, Kazuno Negishi Department of Ophthalmology, Keio

Relation of accommodative microfluctuation with dry eye symptoms in short tear break-up time dry eye

. Resources: Minako Kaido, Yuta Shigeno. Software: Yoshiaki Yamada. Supervision: Kazuo Tsubota. Validation: Minako Kaido. Visualization: Minako Kaido, Motoko Kawashima. Writing ± original draft: Minako ... Kaido. Writing ± review & editing: Motoko Kawashima, Yoshiaki Yamada, Kazuo Tsubota. 11 / 13 25. Watanabe H. Significance of mucin on the ocular surface. Cornea. 2002; 21:S17±S22. PMID: 11995804 12 / 13

Clinical Evaluation of a Royal Jelly Supplementation for the Restoration of Dry Eye: A Prospective Randomized Double Blind Placebo Controlled Study and an Experimental Mouse Model

Background Dry eye is a multifactorial disease characterized by ocular discomfort and visual impairment. Lacrimal gland function has been shown to decrease with aging, a known potent risk factor for dry eye. We have previously found that orally administrated royal jelly (RJ) restored tear secretion in a rat model of dry eye. Methods and Findings We examined the effects of RJ oral...

Assessment of quality of life in patients with visual impairments using a new visual function questionnaire: the VFQ-J11

Assessment of quality of life in patients with visual impairments using a new visual function questionnaire: the VFQ-J11 Tadashi Nakano,1 Motoko Kawashima,2 Yoshimune Hiratsuka,3 Hiroshi Tamura,4,5

Tear lipid layer deficiency associated with incomplete blinking: A case report

Background Meibomian gland obstruction induces hyposecretion of tear film lipids, which results in lipid layer deficiency and evaporative dry eye. Unfortunately, the importance of blinking in meibomian gland dysfunction has been largely overlooked, and it is not known whether incomplete blinking causes tear lipid deficiency, even in the unobstructed meibomian glands. Case...

Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity

Purpose To investigate whether suppression of blue light can improve visual function in patients with short tear break up time (BUT) dry eye (DE). Methods Twenty-two patients with short BUT DE (10 men, 12 women; mean age, 32.4 ± 6.4 years; age range, 23–43 years) and 18 healthy controls (10 men, 8 women; mean age, 30.1 ± 7.4 years; age range, 20–49 years) underwent functional...

The association of sleep quality with dry eye disease: the Osaka study

The association of sleep quality with dry eye disease: the Osaka study Motoko Kawashima,1 Miki Uchino,1,2 Norihiko Yokoi,3 Yuichi Uchino,1,2 Murat Dogru,1 Aoi Komuro,3 Yukiko Sonomura,3 Hiroaki Kato

High prevalence of sleep and mood disorders in dry eye patients: survey of 1,000 eye clinic visitors

High prevalence of sleep and mood disorders in dry eye patients: survey of 1,000 eye clinic visitors Masahiko Ayaki, Motoko Kawashima, Kazuno Negishi, Kazuo Tsubota Department of Ophthalmology, Keio

Associations between Subjective Happiness and Dry Eye Disease: A New Perspective from the Osaka Study

Importance Dry eye disease has become an important health problem. A lack of concordance between self-reported symptoms and the outcome of dry eye examinations has raised questions about dry eye disease. Objective To explore the association between subjective happiness and objective and subjective symptoms of dry eye disease. Design The study adopted a cross-sectional design...

Lamellar corneal injury by bamboo splinters: a case report

Introduction We report an unusual case of corneal lamellar injury caused by long bamboo splinters. Case presentation A 70-year-old Japanese man visited our hospital with a bamboo injury. Slit lamp examination revealed that a bundle of bamboo splinters had deeply penetrated the corneal stroma of the right eye from the nasal limbus. The splinters were approximately 8 mm in length...

Dietary Lactoferrin Alleviates Age-Related Lacrimal Gland Dysfunction in Mice

Background Decrease in lacrimal gland secretory function is related to age-induced dry eye disease. Lactoferrin, the main glycoprotein component of tears, has multiple functions, including anti-inflammatory effects and the promotion of cell growth. We investigated how oral administration of lactoferrin affects age-related lacrimal dysfunction. Methods and Findings Twelve-month...

Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report

Purpose To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy. Methods Observational case report. Results Stromal edema localized in the graft developed 42 days after ALTK for Avellino corneal dystrophy in a 65-year-old man...