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Search: authors:"Mukesh Gautam"

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Hormone induced differential transcriptome analysis of Sertoli cells during postnatal maturation of rat testes

Contributions Conceptualization: Mukesh Gautam, Indrashis Bhattacharya, Umesh Rai, Subeer S. Majumdar. Data curation: Mukesh Gautam, Indrashis Bhattacharya, Subeer S. Majumdar. Formal analysis: Mukesh Gautam ... , Subeer S. Majumdar. Funding acquisition: Subeer S. Majumdar. Methodology: Mukesh Gautam, Indrashis Bhattacharya, Subeer S. Majumdar. Supervision: Umesh Rai, Subeer S. Majumdar. Validation: Mukesh Gautam

Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms

Mutations in the ALS2 gene result in early-onset amyotrophic lateral sclerosis, infantile-onset ascending hereditary spastic paraplegia and juvenile primary lateral sclerosis, suggesting prominent upper motor neuron involvement. However, the importance of alsin function for corticospinal motor neuron (CSMN) health and stability remains unknown. To date, four separate alsin knockout ...

Transcriptome Analysis of Spermatogenically Regressed, Recrudescent and Active Phase Testis of Seasonally Breeding Wall Lizards Hemidactylus flaviviridis

Background Reptiles are phylogenically important group of organisms as mammals have evolved from them. Wall lizard testis exhibits clearly distinct morphology during various phases of a reproductive cycle making them an interesting model to study regulation of spermatogenesis. Studies on reptile spermatogenesis are negligible hence this study will prove to be an important resource. ...